Treatment of venous ulcers with surgical adhesives derived from snake venom

Detalhes bibliográficos
Autor(a) principal: Gatti, M. A. N. [UNESP]
Data de Publicação: 2009
Outros Autores: Vieira, Leila Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992009000200020
http://hdl.handle.net/11449/11675
Resumo: A Brazilian dictionary states that "ulcer", from the Latin word ulcuserise, is a superficial lesion on skin or mucous membrane characterized by an inflammatory process and loss of tissue. Ulcers are a relatively frequent problem that may be worsen by infection or long-time duration. In these cases, they can represent a serious public health issue, since the increased case number contributes to the burden on the public health service. In recent decades, wound treatment has advanced in technological and scientific aspects regarding both development of new products and techniques. Ongoing research in this area is providing new products for wound treatment. Among newly tested substances that have presented successful results is fibrin glue, a snake venom derivative that promotes reduction of infection and edema as well as bleeding control and pain decrease. Thus, the present study aimed to evaluate fibrin glue effects on ulcers of venous origin in 24 patients that were divided into two groups. The first one (G1) consisted of 11 patients treated without the adhesive while the second group (G2) was composed of 13 persons who were under therapy with the adhesive. The results of this study revealed that patients treated with fibrin glue evolved to a satisfactory healing when compared to the other group. Therefore, fibrin glue is an appropriate alternative for treating leg ulcers with several advantages: easy application, less pain, early hospital discharge, not transmiting diseases, lower cost than the adhesive currently available in Brazil and, finally, it is a Brazilian technology.
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spelling Treatment of venous ulcers with surgical adhesives derived from snake venomsurgical adhesivehealingwoundsvenous ulcerA Brazilian dictionary states that "ulcer", from the Latin word ulcuserise, is a superficial lesion on skin or mucous membrane characterized by an inflammatory process and loss of tissue. Ulcers are a relatively frequent problem that may be worsen by infection or long-time duration. In these cases, they can represent a serious public health issue, since the increased case number contributes to the burden on the public health service. In recent decades, wound treatment has advanced in technological and scientific aspects regarding both development of new products and techniques. Ongoing research in this area is providing new products for wound treatment. Among newly tested substances that have presented successful results is fibrin glue, a snake venom derivative that promotes reduction of infection and edema as well as bleeding control and pain decrease. Thus, the present study aimed to evaluate fibrin glue effects on ulcers of venous origin in 24 patients that were divided into two groups. The first one (G1) consisted of 11 patients treated without the adhesive while the second group (G2) was composed of 13 persons who were under therapy with the adhesive. The results of this study revealed that patients treated with fibrin glue evolved to a satisfactory healing when compared to the other group. Therefore, fibrin glue is an appropriate alternative for treating leg ulcers with several advantages: easy application, less pain, early hospital discharge, not transmiting diseases, lower cost than the adhesive currently available in Brazil and, finally, it is a Brazilian technology.UNESP, Dept Dermatol & Radioterapia, Fac Med Botucatu, BR-18618000 Botucatu, SP, BrazilUNESP, Dept Dermatol & Radioterapia, Fac Med Botucatu, BR-18618000 Botucatu, SP, BrazilUniversidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)Universidade Estadual Paulista (Unesp)Gatti, M. A. N. [UNESP]Vieira, Leila Maria2014-05-20T13:34:05Z2014-05-20T13:34:05Z2009-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article368-368application/pdfhttp://dx.doi.org/10.1590/S1678-91992009000200020Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 2, p. 368-368, 2009.1678-9199http://hdl.handle.net/11449/11675S1678-91992009000200020WOS:000267331800020S1678-91992009000200020-en.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-08-14T18:46:19Zoai:repositorio.unesp.br:11449/11675Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T18:46:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Treatment of venous ulcers with surgical adhesives derived from snake venom
title Treatment of venous ulcers with surgical adhesives derived from snake venom
spellingShingle Treatment of venous ulcers with surgical adhesives derived from snake venom
Gatti, M. A. N. [UNESP]
surgical adhesive
healing
wounds
venous ulcer
title_short Treatment of venous ulcers with surgical adhesives derived from snake venom
title_full Treatment of venous ulcers with surgical adhesives derived from snake venom
title_fullStr Treatment of venous ulcers with surgical adhesives derived from snake venom
title_full_unstemmed Treatment of venous ulcers with surgical adhesives derived from snake venom
title_sort Treatment of venous ulcers with surgical adhesives derived from snake venom
author Gatti, M. A. N. [UNESP]
author_facet Gatti, M. A. N. [UNESP]
Vieira, Leila Maria
author_role author
author2 Vieira, Leila Maria
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Gatti, M. A. N. [UNESP]
Vieira, Leila Maria
dc.subject.por.fl_str_mv surgical adhesive
healing
wounds
venous ulcer
topic surgical adhesive
healing
wounds
venous ulcer
description A Brazilian dictionary states that "ulcer", from the Latin word ulcuserise, is a superficial lesion on skin or mucous membrane characterized by an inflammatory process and loss of tissue. Ulcers are a relatively frequent problem that may be worsen by infection or long-time duration. In these cases, they can represent a serious public health issue, since the increased case number contributes to the burden on the public health service. In recent decades, wound treatment has advanced in technological and scientific aspects regarding both development of new products and techniques. Ongoing research in this area is providing new products for wound treatment. Among newly tested substances that have presented successful results is fibrin glue, a snake venom derivative that promotes reduction of infection and edema as well as bleeding control and pain decrease. Thus, the present study aimed to evaluate fibrin glue effects on ulcers of venous origin in 24 patients that were divided into two groups. The first one (G1) consisted of 11 patients treated without the adhesive while the second group (G2) was composed of 13 persons who were under therapy with the adhesive. The results of this study revealed that patients treated with fibrin glue evolved to a satisfactory healing when compared to the other group. Therefore, fibrin glue is an appropriate alternative for treating leg ulcers with several advantages: easy application, less pain, early hospital discharge, not transmiting diseases, lower cost than the adhesive currently available in Brazil and, finally, it is a Brazilian technology.
publishDate 2009
dc.date.none.fl_str_mv 2009-01-01
2014-05-20T13:34:05Z
2014-05-20T13:34:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992009000200020
Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 2, p. 368-368, 2009.
1678-9199
http://hdl.handle.net/11449/11675
S1678-91992009000200020
WOS:000267331800020
S1678-91992009000200020-en.pdf
url http://dx.doi.org/10.1590/S1678-91992009000200020
http://hdl.handle.net/11449/11675
identifier_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 15, n. 2, p. 368-368, 2009.
1678-9199
S1678-91992009000200020
WOS:000267331800020
S1678-91992009000200020-en.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins Including Tropical Diseases
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 368-368
application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)
publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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