Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.theriogenology.2012.02.031 http://hdl.handle.net/11449/14820 |
Resumo: | The effects of estradiol benzoate (EB) and estradiol cypionate (EC) on induction of ovulation after a synchronized LH surge and on fertility of Bos indicus females submitted to timed AI (TAI) were evaluated. In Experiment 1, ovariectomized Nelore heifers were used to evaluate the effect of EB (n = 5) and EC (n = 5) on the circulating LH profile. The LH surge timing (19.6 and 50.5 h; P = 0.001), magnitude (20.5 and 9.4 ng/mL; P = 0.005), duration (8.6 and 16.5 h; P = 0.001), and area under the LH curve (158.6 and 339.4 ng/mL; P = 0.01) differed between the EB and EC treatments, respectively. In Experiment 2 (follicular responses; n = 60) and 3 (pregnancy per AI; P/AI; n = 953) suckled Bos indicus beef cows submitted to an estradiol/progesterone-based synchronization protocol were assigned to receive one of two treatments to induce synchronized ovulation: 1 mg of EB im 24 h after progesterone (P4) device removal or 1 mg of EC im at P4 device removal. There was no difference (P > 0.05) between EB and EC treatments on follicular responses (maximum diameter of the ovulatory follicle, 13.1 vs. 13.9 mm; interval from progesterone device removal to ovulation, 70.2 vs. 68.5 h; and ovulation rate, 77.8 vs. 82.8%, respectively). In addition, P/AI was similar (P < 0.22) between the cows treated with EB (57.5%; 277/482) and EC (61.8%; 291/471). In conclusion, despite pharmacologic differences, both esters of estradiol administered either at P4 device removal (EC) or 24 h later (EB) were effective in inducing an LH surge which resulted in synchronized ovulations and similar P/AI in suckled Bos indicus beef cows submitted to TAI. (C) 2012 Elsevier B.V. All rights reserved. |
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Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocolBovineOvarian responseEstradiolTaiLHSynchronizationThe effects of estradiol benzoate (EB) and estradiol cypionate (EC) on induction of ovulation after a synchronized LH surge and on fertility of Bos indicus females submitted to timed AI (TAI) were evaluated. In Experiment 1, ovariectomized Nelore heifers were used to evaluate the effect of EB (n = 5) and EC (n = 5) on the circulating LH profile. The LH surge timing (19.6 and 50.5 h; P = 0.001), magnitude (20.5 and 9.4 ng/mL; P = 0.005), duration (8.6 and 16.5 h; P = 0.001), and area under the LH curve (158.6 and 339.4 ng/mL; P = 0.01) differed between the EB and EC treatments, respectively. In Experiment 2 (follicular responses; n = 60) and 3 (pregnancy per AI; P/AI; n = 953) suckled Bos indicus beef cows submitted to an estradiol/progesterone-based synchronization protocol were assigned to receive one of two treatments to induce synchronized ovulation: 1 mg of EB im 24 h after progesterone (P4) device removal or 1 mg of EC im at P4 device removal. There was no difference (P > 0.05) between EB and EC treatments on follicular responses (maximum diameter of the ovulatory follicle, 13.1 vs. 13.9 mm; interval from progesterone device removal to ovulation, 70.2 vs. 68.5 h; and ovulation rate, 77.8 vs. 82.8%, respectively). In addition, P/AI was similar (P < 0.22) between the cows treated with EB (57.5%; 277/482) and EC (61.8%; 291/471). In conclusion, despite pharmacologic differences, both esters of estradiol administered either at P4 device removal (EC) or 24 h later (EB) were effective in inducing an LH surge which resulted in synchronized ovulations and similar P/AI in suckled Bos indicus beef cows submitted to TAI. (C) 2012 Elsevier B.V. All rights reserved.Ourofino Agronegocio (Cravinhos, SP, Brazil)RG Genetica Avancada (Agua Boa, MS, Brazil)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ São Paulo, FMVZ, Dept Anim Reprod, BR-09500900 São Paulo, BrazilAPTA Vale Paraiba Reg Ctr, Pindamonhangaba, SP, BrazilOuro Fino Saúde Anim, Ribeirao Preto, SP, BrazilUNESP, Dept Support Anim Prod & Hlth, Aracatuba, SP, BrazilUniversidade Federal de Lavras (UFLA), Dept Anim Sci, Lavras, MG, BrazilUFPB, Ctr Vet Sci, Areia, PB, BrazilUNESP, Dept Support Anim Prod & Hlth, Aracatuba, SP, BrazilElsevier B.V.Universidade Estadual Paulista (Unesp)Agência Paulista de Tecnologia dos Agronegócios (APTA)Ouro Fino Saúde AnimUniversidade Federal de Lavras (UFLA)Universidade Federal da Paraíba (UFPB)Sales, J. N. S.Carvalho, J. B. P.Crepaldi, G. A.Cipriano, R. S. [UNESP]Jacomini, J. O.Maio, J. R. G.Souza, J. C.Nogueira, Guilherme de Paula [UNESP]Baruselli, P. S.2013-09-30T18:25:16Z2014-05-20T13:42:37Z2013-09-30T18:25:16Z2014-05-20T13:42:37Z2012-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article510-516application/pdfhttp://dx.doi.org/10.1016/j.theriogenology.2012.02.031Theriogenology. New York: Elsevier B.V., v. 78, n. 3, p. 510-516, 2012.0093-691Xhttp://hdl.handle.net/11449/1482010.1016/j.theriogenology.2012.02.031WOS:000306538100005WOS000306538100005.pdf6926188473133379Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTheriogenology2.136info:eu-repo/semantics/openAccess2024-09-04T19:14:57Zoai:repositorio.unesp.br:11449/14820Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T19:14:57Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
title |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
spellingShingle |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol Sales, J. N. S. Bovine Ovarian response Estradiol Tai LH Synchronization |
title_short |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
title_full |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
title_fullStr |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
title_full_unstemmed |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
title_sort |
Effects of two estradiol esters (benzoate and cypionate) on the induction of synchronized ovulations in Bos indicus cows submitted to a timed artificial insemination protocol |
author |
Sales, J. N. S. |
author_facet |
Sales, J. N. S. Carvalho, J. B. P. Crepaldi, G. A. Cipriano, R. S. [UNESP] Jacomini, J. O. Maio, J. R. G. Souza, J. C. Nogueira, Guilherme de Paula [UNESP] Baruselli, P. S. |
author_role |
author |
author2 |
Carvalho, J. B. P. Crepaldi, G. A. Cipriano, R. S. [UNESP] Jacomini, J. O. Maio, J. R. G. Souza, J. C. Nogueira, Guilherme de Paula [UNESP] Baruselli, P. S. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Agência Paulista de Tecnologia dos Agronegócios (APTA) Ouro Fino Saúde Anim Universidade Federal de Lavras (UFLA) Universidade Federal da Paraíba (UFPB) |
dc.contributor.author.fl_str_mv |
Sales, J. N. S. Carvalho, J. B. P. Crepaldi, G. A. Cipriano, R. S. [UNESP] Jacomini, J. O. Maio, J. R. G. Souza, J. C. Nogueira, Guilherme de Paula [UNESP] Baruselli, P. S. |
dc.subject.por.fl_str_mv |
Bovine Ovarian response Estradiol Tai LH Synchronization |
topic |
Bovine Ovarian response Estradiol Tai LH Synchronization |
description |
The effects of estradiol benzoate (EB) and estradiol cypionate (EC) on induction of ovulation after a synchronized LH surge and on fertility of Bos indicus females submitted to timed AI (TAI) were evaluated. In Experiment 1, ovariectomized Nelore heifers were used to evaluate the effect of EB (n = 5) and EC (n = 5) on the circulating LH profile. The LH surge timing (19.6 and 50.5 h; P = 0.001), magnitude (20.5 and 9.4 ng/mL; P = 0.005), duration (8.6 and 16.5 h; P = 0.001), and area under the LH curve (158.6 and 339.4 ng/mL; P = 0.01) differed between the EB and EC treatments, respectively. In Experiment 2 (follicular responses; n = 60) and 3 (pregnancy per AI; P/AI; n = 953) suckled Bos indicus beef cows submitted to an estradiol/progesterone-based synchronization protocol were assigned to receive one of two treatments to induce synchronized ovulation: 1 mg of EB im 24 h after progesterone (P4) device removal or 1 mg of EC im at P4 device removal. There was no difference (P > 0.05) between EB and EC treatments on follicular responses (maximum diameter of the ovulatory follicle, 13.1 vs. 13.9 mm; interval from progesterone device removal to ovulation, 70.2 vs. 68.5 h; and ovulation rate, 77.8 vs. 82.8%, respectively). In addition, P/AI was similar (P < 0.22) between the cows treated with EB (57.5%; 277/482) and EC (61.8%; 291/471). In conclusion, despite pharmacologic differences, both esters of estradiol administered either at P4 device removal (EC) or 24 h later (EB) were effective in inducing an LH surge which resulted in synchronized ovulations and similar P/AI in suckled Bos indicus beef cows submitted to TAI. (C) 2012 Elsevier B.V. All rights reserved. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-08-01 2013-09-30T18:25:16Z 2013-09-30T18:25:16Z 2014-05-20T13:42:37Z 2014-05-20T13:42:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.theriogenology.2012.02.031 Theriogenology. New York: Elsevier B.V., v. 78, n. 3, p. 510-516, 2012. 0093-691X http://hdl.handle.net/11449/14820 10.1016/j.theriogenology.2012.02.031 WOS:000306538100005 WOS000306538100005.pdf 6926188473133379 |
url |
http://dx.doi.org/10.1016/j.theriogenology.2012.02.031 http://hdl.handle.net/11449/14820 |
identifier_str_mv |
Theriogenology. New York: Elsevier B.V., v. 78, n. 3, p. 510-516, 2012. 0093-691X 10.1016/j.theriogenology.2012.02.031 WOS:000306538100005 WOS000306538100005.pdf 6926188473133379 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Theriogenology 2.136 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
510-516 application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021363556024320 |