QTL affecting body weight in a candidate region of cattle chromosome 5

Detalhes bibliográficos
Autor(a) principal: Machado, Mariana B. B.
Data de Publicação: 2003
Outros Autores: Alencar, Maurício M., Pereira, Andréa P., Oliveira, Henrique Nunes de [UNESP], Casas, Eduardo, Coutinho, Luis L., Regitano, Luciana C. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1415-47572003000300008
http://hdl.handle.net/11449/30467
Resumo: The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.
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spelling QTL affecting body weight in a candidate region of cattle chromosome 5QTLgrowth traitsMicrosatelliteBovineThe objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Carlos (UFSCar) Departamento de Genética e EvoluçãoEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Pecuária SudesteUniversidade Estadual de São Paulo Departamento de Reprodução e Nutrição AnimalU.S. Meat Animal Research CenterUniversidade de São Paulo Departamento de Produção AnimalSociedade Brasileira de GenéticaUniversidade Federal de São Carlos (UFSCar)Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Universidade Estadual Paulista (Unesp)U.S. Meat Animal Research CenterUniversidade de São Paulo (USP)Machado, Mariana B. B.Alencar, Maurício M.Pereira, Andréa P.Oliveira, Henrique Nunes de [UNESP]Casas, EduardoCoutinho, Luis L.Regitano, Luciana C. A.2014-05-20T15:17:25Z2014-05-20T15:17:25Z2003-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article259-265application/pdfhttp://dx.doi.org/10.1590/S1415-47572003000300008Genetics and Molecular Biology. Sociedade Brasileira de Genética, v. 26, n. 3, p. 259-265, 2003.1415-4757http://hdl.handle.net/11449/3046710.1590/S1415-47572003000300008S1415-47572003000300008S1415-47572003000300008.pdf5593441035110683SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengGenetics and Molecular Biology1.4930,638info:eu-repo/semantics/openAccess2024-06-07T18:41:05Zoai:repositorio.unesp.br:11449/30467Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:59:58.866995Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv QTL affecting body weight in a candidate region of cattle chromosome 5
title QTL affecting body weight in a candidate region of cattle chromosome 5
spellingShingle QTL affecting body weight in a candidate region of cattle chromosome 5
Machado, Mariana B. B.
QTL
growth traits
Microsatellite
Bovine
title_short QTL affecting body weight in a candidate region of cattle chromosome 5
title_full QTL affecting body weight in a candidate region of cattle chromosome 5
title_fullStr QTL affecting body weight in a candidate region of cattle chromosome 5
title_full_unstemmed QTL affecting body weight in a candidate region of cattle chromosome 5
title_sort QTL affecting body weight in a candidate region of cattle chromosome 5
author Machado, Mariana B. B.
author_facet Machado, Mariana B. B.
Alencar, Maurício M.
Pereira, Andréa P.
Oliveira, Henrique Nunes de [UNESP]
Casas, Eduardo
Coutinho, Luis L.
Regitano, Luciana C. A.
author_role author
author2 Alencar, Maurício M.
Pereira, Andréa P.
Oliveira, Henrique Nunes de [UNESP]
Casas, Eduardo
Coutinho, Luis L.
Regitano, Luciana C. A.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Carlos (UFSCar)
Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
Universidade Estadual Paulista (Unesp)
U.S. Meat Animal Research Center
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Machado, Mariana B. B.
Alencar, Maurício M.
Pereira, Andréa P.
Oliveira, Henrique Nunes de [UNESP]
Casas, Eduardo
Coutinho, Luis L.
Regitano, Luciana C. A.
dc.subject.por.fl_str_mv QTL
growth traits
Microsatellite
Bovine
topic QTL
growth traits
Microsatellite
Bovine
description The objective of this work was to identify QTLs for liveweight in a candidate region of bovine chromosome 5. Half-sib families from two lines, one traditional and the other new, of Canchim beef cattle (5/8 Charolais + 3/8 Zebu) were genotyped for four microsatellite markers, including the microsatellite in the IGF-1 (insulin-like growth factor-1) promoter region. Significant differences in allele distribution between the two lines were found for three markers. Interval mapping analyses in this region indicated the presence of a QTL controlling birth weight (p < 0.05) and of a QTL influencing breeding value for yearling weight (p < 0.01) in the newer line of the breed. The previously identified interaction between the IGF-1 genotype and genetic group strengthens the hypothesis of a linked QTL rather than an IGF-1 effect on growth traits in the Canchim cattle.
publishDate 2003
dc.date.none.fl_str_mv 2003-01-01
2014-05-20T15:17:25Z
2014-05-20T15:17:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1415-47572003000300008
Genetics and Molecular Biology. Sociedade Brasileira de Genética, v. 26, n. 3, p. 259-265, 2003.
1415-4757
http://hdl.handle.net/11449/30467
10.1590/S1415-47572003000300008
S1415-47572003000300008
S1415-47572003000300008.pdf
5593441035110683
url http://dx.doi.org/10.1590/S1415-47572003000300008
http://hdl.handle.net/11449/30467
identifier_str_mv Genetics and Molecular Biology. Sociedade Brasileira de Genética, v. 26, n. 3, p. 259-265, 2003.
1415-4757
10.1590/S1415-47572003000300008
S1415-47572003000300008
S1415-47572003000300008.pdf
5593441035110683
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Genetics and Molecular Biology
1.493
0,638
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 259-265
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128734477156352

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