Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1076/brhm.27.3.245.12963 http://hdl.handle.net/11449/219187 |
Resumo: | Nucleus raphe pallidus (RPa) lies ventrally in the caudal brainstem, where it is coextensive rostrally with the nucleus raphe magnus (RMg) and caudally with the nucleus raphe obscurus (ROb). Retrograde neuronal tracing studies of our laboratory, carried out in rats and presented elsewhere, with fluorogold, true-blue or fast-blue, iontophoretically injected or by crystalline deposit, along the RPa extent, displayed many labeled pericaria at the preoptic area (POA), as well as lateral (LH) and dorsomedial (DMH) hypothalamus; paraventricular nucleus (PVN) and dorsal (DR) and median (MnR) raphe nuclei among others structures. In addition, RPa which projects to the intermediolateral column, has been demonstrated to bear relation to many of the somatic-visceral functions also reported for POA. Iontophoretic injections of PHA-L, an anterograde tracer, in the POA subnuclei, presented terminal and varicose labeled fibers in RPa, as well as in the RMg, ROb, paraventricular thalamic (PVA), PVN and supraoptic nucleus (SO), LH, subparaventricular zone (sPVZ) and locus cocruleus (LC), POA, PVA, PVN, LH and SO have been described as retino- and suprachiasmatic-recipients. Taken together, these neuronal connections between brainstem raphe nuclei and POA, the similarity of functions to which they are related, as well as connections with other retino-suprachiasmatic-recipient structures, suggest that these caudal brainstem raphe nuclei could be part of the output system for the expression of some biological rhythms. |
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Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythmsBiological rhythmsbrainstemPHA-Lpreoptic arearaphe-nucleiserotoninNucleus raphe pallidus (RPa) lies ventrally in the caudal brainstem, where it is coextensive rostrally with the nucleus raphe magnus (RMg) and caudally with the nucleus raphe obscurus (ROb). Retrograde neuronal tracing studies of our laboratory, carried out in rats and presented elsewhere, with fluorogold, true-blue or fast-blue, iontophoretically injected or by crystalline deposit, along the RPa extent, displayed many labeled pericaria at the preoptic area (POA), as well as lateral (LH) and dorsomedial (DMH) hypothalamus; paraventricular nucleus (PVN) and dorsal (DR) and median (MnR) raphe nuclei among others structures. In addition, RPa which projects to the intermediolateral column, has been demonstrated to bear relation to many of the somatic-visceral functions also reported for POA. Iontophoretic injections of PHA-L, an anterograde tracer, in the POA subnuclei, presented terminal and varicose labeled fibers in RPa, as well as in the RMg, ROb, paraventricular thalamic (PVA), PVN and supraoptic nucleus (SO), LH, subparaventricular zone (sPVZ) and locus cocruleus (LC), POA, PVA, PVN, LH and SO have been described as retino- and suprachiasmatic-recipients. Taken together, these neuronal connections between brainstem raphe nuclei and POA, the similarity of functions to which they are related, as well as connections with other retino-suprachiasmatic-recipient structures, suggest that these caudal brainstem raphe nuclei could be part of the output system for the expression of some biological rhythms.Departamento de Fisiologia e Biofísica IB-UNICAMP Universidade Estadual de CampinasDepartamento de Anatomia ICB-USPDepartamento de Fisiologia e Biofisica ICB-USP Universidade Estadual de São Paulo, São PauloDepartamento de Fisiologia e Biofísica-UNICAMP Universidade Estadual de Campinas, São PauloDepartamento de Fisiologia e Biofisica ICB-USP Universidade Estadual de São Paulo, São PauloUniversidade Estadual de Campinas (UNICAMP)Universidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Nogueira, Maria InêsPfeiffer, Claudia PerpétueBittencourt, Jackson CioniRibeiro Do Vale, Luis Eduardo [UNESP]2022-04-28T18:54:09Z2022-04-28T18:54:09Z1996-11-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObject245-260http://dx.doi.org/10.1076/brhm.27.3.245.12963Biological Rhythm Research, v. 27, n. 3, p. 245-260, 1996.0929-1016http://hdl.handle.net/11449/21918710.1076/brhm.27.3.245.129632-s2.0-0029862001Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiological Rhythm Researchinfo:eu-repo/semantics/openAccess2022-04-28T18:54:09Zoai:repositorio.unesp.br:11449/219187Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:04:11.633423Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
title |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
spellingShingle |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms Nogueira, Maria Inês Biological rhythms brainstem PHA-L preoptic area raphe-nuclei serotonin |
title_short |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
title_full |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
title_fullStr |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
title_full_unstemmed |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
title_sort |
Caudal brainstem raphe nuclei: Neural substrate for their involvement in the expression of some biological rhythms |
author |
Nogueira, Maria Inês |
author_facet |
Nogueira, Maria Inês Pfeiffer, Claudia Perpétue Bittencourt, Jackson Cioni Ribeiro Do Vale, Luis Eduardo [UNESP] |
author_role |
author |
author2 |
Pfeiffer, Claudia Perpétue Bittencourt, Jackson Cioni Ribeiro Do Vale, Luis Eduardo [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual de Campinas (UNICAMP) Universidade de São Paulo (USP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Nogueira, Maria Inês Pfeiffer, Claudia Perpétue Bittencourt, Jackson Cioni Ribeiro Do Vale, Luis Eduardo [UNESP] |
dc.subject.por.fl_str_mv |
Biological rhythms brainstem PHA-L preoptic area raphe-nuclei serotonin |
topic |
Biological rhythms brainstem PHA-L preoptic area raphe-nuclei serotonin |
description |
Nucleus raphe pallidus (RPa) lies ventrally in the caudal brainstem, where it is coextensive rostrally with the nucleus raphe magnus (RMg) and caudally with the nucleus raphe obscurus (ROb). Retrograde neuronal tracing studies of our laboratory, carried out in rats and presented elsewhere, with fluorogold, true-blue or fast-blue, iontophoretically injected or by crystalline deposit, along the RPa extent, displayed many labeled pericaria at the preoptic area (POA), as well as lateral (LH) and dorsomedial (DMH) hypothalamus; paraventricular nucleus (PVN) and dorsal (DR) and median (MnR) raphe nuclei among others structures. In addition, RPa which projects to the intermediolateral column, has been demonstrated to bear relation to many of the somatic-visceral functions also reported for POA. Iontophoretic injections of PHA-L, an anterograde tracer, in the POA subnuclei, presented terminal and varicose labeled fibers in RPa, as well as in the RMg, ROb, paraventricular thalamic (PVA), PVN and supraoptic nucleus (SO), LH, subparaventricular zone (sPVZ) and locus cocruleus (LC), POA, PVA, PVN, LH and SO have been described as retino- and suprachiasmatic-recipients. Taken together, these neuronal connections between brainstem raphe nuclei and POA, the similarity of functions to which they are related, as well as connections with other retino-suprachiasmatic-recipient structures, suggest that these caudal brainstem raphe nuclei could be part of the output system for the expression of some biological rhythms. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-11-14 2022-04-28T18:54:09Z 2022-04-28T18:54:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1076/brhm.27.3.245.12963 Biological Rhythm Research, v. 27, n. 3, p. 245-260, 1996. 0929-1016 http://hdl.handle.net/11449/219187 10.1076/brhm.27.3.245.12963 2-s2.0-0029862001 |
url |
http://dx.doi.org/10.1076/brhm.27.3.245.12963 http://hdl.handle.net/11449/219187 |
identifier_str_mv |
Biological Rhythm Research, v. 27, n. 3, p. 245-260, 1996. 0929-1016 10.1076/brhm.27.3.245.12963 2-s2.0-0029862001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Biological Rhythm Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
245-260 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129487273984000 |