Algicidal effect of blue light on pathogenic Prototheca species
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.pdpdt.2019.04.009 http://hdl.handle.net/11449/189702 |
Resumo: | Prototheca spp. are pathogenic algae with important zoonotic potential. Most importantly, these algae often infect dairy cattle. Since there is no effective therapy against the algae, the standard recommendation is the disposal or culling of infected cows to avoid outbreaks. This study investigated the ability of blue light to inactivate pathogenic Prototheca species. Blue LED light (λ = 410 nm) was used to inactivate in vitro suspensions of P. zopfii genotypes 1 and 2, and P. blaschkeae. Our results showed that blue light irradiation induced a strain-specific dose-dependent algicidal effect against all tested strains. P. zopfii genotype 1, was more sensitive than genotype 2 and P. blaschkeae was the most tolerant. Even though we observed different inactivation kinetics, all strains presented significant photoinactivation levels within feasible procedure periods. Therefore, we conclude that blue light irradiation offers promising potential for the development of novel technologies that control contaminations and infections caused by Prototheca spp. |
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Algicidal effect of blue light on pathogenic Prototheca speciesAlgae decontaminationAntimicrobial Photodynamic TherapyBovine protothecosisPhotoinactivationPrototheca blaschkeaePrototheca zopfiiVeterinary medicinePrototheca spp. are pathogenic algae with important zoonotic potential. Most importantly, these algae often infect dairy cattle. Since there is no effective therapy against the algae, the standard recommendation is the disposal or culling of infected cows to avoid outbreaks. This study investigated the ability of blue light to inactivate pathogenic Prototheca species. Blue LED light (λ = 410 nm) was used to inactivate in vitro suspensions of P. zopfii genotypes 1 and 2, and P. blaschkeae. Our results showed that blue light irradiation induced a strain-specific dose-dependent algicidal effect against all tested strains. P. zopfii genotype 1, was more sensitive than genotype 2 and P. blaschkeae was the most tolerant. Even though we observed different inactivation kinetics, all strains presented significant photoinactivation levels within feasible procedure periods. Therefore, we conclude that blue light irradiation offers promising potential for the development of novel technologies that control contaminations and infections caused by Prototheca spp.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Internal Medicine School of Veterinary Medicine and Animal Science University of Sao PauloDepartment of Microbiology Institute for Biomedical Sciences University of Sao PauloDepartment of Clinical and Toxicological Analysis School of Pharmaceutical Sciences University of Sao PauloDepartment of Veterinary Hygiene and Public Health Sao Paulo State University (UNESP)Department of Applied Microbiology Institute of Microbiology Faculty of Biology University of WarsawBioLambda Scientific and Commercial LTDDepartment of Veterinary Hygiene and Public Health Sao Paulo State University (UNESP)FAPESP: 2016/25095-2Universidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)University of WarsawScientific and Commercial LTDdos Anjos, CarolinaSellera, Fábio ParraGargano, Ronaldo GomesLincopan, NiltonPogliani, Fabio CelidonioRibeiro, Marcio Garcia [UNESP]Jagielski, TomaszSabino, Caetano Padial2019-10-06T16:49:27Z2019-10-06T16:49:27Z2019-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article210-213http://dx.doi.org/10.1016/j.pdpdt.2019.04.009Photodiagnosis and Photodynamic Therapy, v. 26, p. 210-213.1873-15971572-1000http://hdl.handle.net/11449/18970210.1016/j.pdpdt.2019.04.0092-s2.0-8506422529622091243172737972209124317273797Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPhotodiagnosis and Photodynamic Therapyinfo:eu-repo/semantics/openAccess2021-10-23T18:56:51Zoai:repositorio.unesp.br:11449/189702Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T18:56:51Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Algicidal effect of blue light on pathogenic Prototheca species |
title |
Algicidal effect of blue light on pathogenic Prototheca species |
spellingShingle |
Algicidal effect of blue light on pathogenic Prototheca species dos Anjos, Carolina Algae decontamination Antimicrobial Photodynamic Therapy Bovine protothecosis Photoinactivation Prototheca blaschkeae Prototheca zopfii Veterinary medicine |
title_short |
Algicidal effect of blue light on pathogenic Prototheca species |
title_full |
Algicidal effect of blue light on pathogenic Prototheca species |
title_fullStr |
Algicidal effect of blue light on pathogenic Prototheca species |
title_full_unstemmed |
Algicidal effect of blue light on pathogenic Prototheca species |
title_sort |
Algicidal effect of blue light on pathogenic Prototheca species |
author |
dos Anjos, Carolina |
author_facet |
dos Anjos, Carolina Sellera, Fábio Parra Gargano, Ronaldo Gomes Lincopan, Nilton Pogliani, Fabio Celidonio Ribeiro, Marcio Garcia [UNESP] Jagielski, Tomasz Sabino, Caetano Padial |
author_role |
author |
author2 |
Sellera, Fábio Parra Gargano, Ronaldo Gomes Lincopan, Nilton Pogliani, Fabio Celidonio Ribeiro, Marcio Garcia [UNESP] Jagielski, Tomasz Sabino, Caetano Padial |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) University of Warsaw Scientific and Commercial LTD |
dc.contributor.author.fl_str_mv |
dos Anjos, Carolina Sellera, Fábio Parra Gargano, Ronaldo Gomes Lincopan, Nilton Pogliani, Fabio Celidonio Ribeiro, Marcio Garcia [UNESP] Jagielski, Tomasz Sabino, Caetano Padial |
dc.subject.por.fl_str_mv |
Algae decontamination Antimicrobial Photodynamic Therapy Bovine protothecosis Photoinactivation Prototheca blaschkeae Prototheca zopfii Veterinary medicine |
topic |
Algae decontamination Antimicrobial Photodynamic Therapy Bovine protothecosis Photoinactivation Prototheca blaschkeae Prototheca zopfii Veterinary medicine |
description |
Prototheca spp. are pathogenic algae with important zoonotic potential. Most importantly, these algae often infect dairy cattle. Since there is no effective therapy against the algae, the standard recommendation is the disposal or culling of infected cows to avoid outbreaks. This study investigated the ability of blue light to inactivate pathogenic Prototheca species. Blue LED light (λ = 410 nm) was used to inactivate in vitro suspensions of P. zopfii genotypes 1 and 2, and P. blaschkeae. Our results showed that blue light irradiation induced a strain-specific dose-dependent algicidal effect against all tested strains. P. zopfii genotype 1, was more sensitive than genotype 2 and P. blaschkeae was the most tolerant. Even though we observed different inactivation kinetics, all strains presented significant photoinactivation levels within feasible procedure periods. Therefore, we conclude that blue light irradiation offers promising potential for the development of novel technologies that control contaminations and infections caused by Prototheca spp. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T16:49:27Z 2019-10-06T16:49:27Z 2019-06-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.pdpdt.2019.04.009 Photodiagnosis and Photodynamic Therapy, v. 26, p. 210-213. 1873-1597 1572-1000 http://hdl.handle.net/11449/189702 10.1016/j.pdpdt.2019.04.009 2-s2.0-85064225296 2209124317273797 2209124317273797 |
url |
http://dx.doi.org/10.1016/j.pdpdt.2019.04.009 http://hdl.handle.net/11449/189702 |
identifier_str_mv |
Photodiagnosis and Photodynamic Therapy, v. 26, p. 210-213. 1873-1597 1572-1000 10.1016/j.pdpdt.2019.04.009 2-s2.0-85064225296 2209124317273797 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Photodiagnosis and Photodynamic Therapy |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
210-213 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964670460690432 |