Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.21577/0103-5053.20220095 http://hdl.handle.net/11449/237780 |
Resumo: | This study aims to analyze Tetragonisca angustula honey from southwestern Bahia for its physicochemical characteristics, phenolic compounds and glioma cell inhibitory effect, in samples from different periods of the year, dry (DP) and rainy (RP) period. The analyses showed that samples obtained in the DP and RP are statistically different for the physicochemical profile (p 0.05). DP honey has a darker color, greater acidity, content of reducing sugars and ash and lower moisture, when compared to RP. The content of total phenolics and flavonoids was determined spectrometrically, using the Folin-Ciocalteu method and reaction with aluminum chloride, respectively, and there was no statistical difference between the samples (p 0.05). For the extraction of phenolic compounds, dispersive liquid-liquid microextraction was used, besides analysis by high-performance liquid chromatography with ultraviolet detection (HPLC-UV), which identified chlorogenic acid and quantified caffeic acid and rutin (1.7723 and 0.9384 ??g 100 mg-1 honey, respectively). Glioma cell inhibition effect lines were observed for DP at concentrations 1000 ng mL-1 of honey. Principal component analysis (PCA) proposes the physicochemical parameters as the main distinguishing factors between the DP and RP samples. DP samples showed similarity for the parameters ash content, acidity and reducing sugars and the samples of the RP had consonance between pH and moisture. |
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Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory EffectTetragonisca angustulaHoney propertiesPhenolic compoundsGlioma cells inhibitionDLLMEPCAThis study aims to analyze Tetragonisca angustula honey from southwestern Bahia for its physicochemical characteristics, phenolic compounds and glioma cell inhibitory effect, in samples from different periods of the year, dry (DP) and rainy (RP) period. The analyses showed that samples obtained in the DP and RP are statistically different for the physicochemical profile (p 0.05). DP honey has a darker color, greater acidity, content of reducing sugars and ash and lower moisture, when compared to RP. The content of total phenolics and flavonoids was determined spectrometrically, using the Folin-Ciocalteu method and reaction with aluminum chloride, respectively, and there was no statistical difference between the samples (p 0.05). For the extraction of phenolic compounds, dispersive liquid-liquid microextraction was used, besides analysis by high-performance liquid chromatography with ultraviolet detection (HPLC-UV), which identified chlorogenic acid and quantified caffeic acid and rutin (1.7723 and 0.9384 ??g 100 mg-1 honey, respectively). Glioma cell inhibition effect lines were observed for DP at concentrations 1000 ng mL-1 of honey. Principal component analysis (PCA) proposes the physicochemical parameters as the main distinguishing factors between the DP and RP samples. DP samples showed similarity for the parameters ash content, acidity and reducing sugars and the samples of the RP had consonance between pH and moisture.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual do Sudoeste da Bahia (UESB)Univ Estadual Sudoeste Bahia, Dept Ciencias & Tecnol, Programa Posgrad Quim, BR-45208091 Jequie, BA, BrazilFac Anisio Teixeira, Ctr Estadual Educ Profiss Saude Anisio Teixeira, BR-40313430 Salvador, BA, BrazilUniv Estadual Paulista, Dept Engn Rural, BR-18610034 Botucatu, SP, BrazilUniv Estadual Paulista, Dept Engn Rural, BR-18610034 Botucatu, SP, BrazilCAPES: 001Soc Brasileira QuimicaUniv Estadual Sudoeste BahiaFac Anisio TeixeiraUniversidade Estadual Paulista (UNESP)Ferreira, Adrianne B.Novaes, Cleber G.Jesus, Hion O. deBorges, Julita Maria P.Ramos, Florisvaldo S.Pereira, Anderson J. [UNESP]Oliveira, Djalma M. deAguiar, Rosane M.2022-11-30T13:44:46Z2022-11-30T13:44:46Z2022-07-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11http://dx.doi.org/10.21577/0103-5053.20220095Journal Of The Brazilian Chemical Society. Sao Paulo: Soc Brasileira Quimica, 11 p., 2022.0103-5053http://hdl.handle.net/11449/23778010.21577/0103-5053.20220095WOS:000823678400001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of The Brazilian Chemical Societyinfo:eu-repo/semantics/openAccess2024-04-30T14:01:04Zoai:repositorio.unesp.br:11449/237780Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:50:58.797961Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
title |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
spellingShingle |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect Ferreira, Adrianne B. Tetragonisca angustula Honey properties Phenolic compounds Glioma cells inhibition DLLME PCA |
title_short |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
title_full |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
title_fullStr |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
title_full_unstemmed |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
title_sort |
Honey of Tetragonisca angustula from Southwestern Bahia: Influence of Seasonality on the Physicochemical Profile and Glioma Cell Inhibitory Effect |
author |
Ferreira, Adrianne B. |
author_facet |
Ferreira, Adrianne B. Novaes, Cleber G. Jesus, Hion O. de Borges, Julita Maria P. Ramos, Florisvaldo S. Pereira, Anderson J. [UNESP] Oliveira, Djalma M. de Aguiar, Rosane M. |
author_role |
author |
author2 |
Novaes, Cleber G. Jesus, Hion O. de Borges, Julita Maria P. Ramos, Florisvaldo S. Pereira, Anderson J. [UNESP] Oliveira, Djalma M. de Aguiar, Rosane M. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Univ Estadual Sudoeste Bahia Fac Anisio Teixeira Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Ferreira, Adrianne B. Novaes, Cleber G. Jesus, Hion O. de Borges, Julita Maria P. Ramos, Florisvaldo S. Pereira, Anderson J. [UNESP] Oliveira, Djalma M. de Aguiar, Rosane M. |
dc.subject.por.fl_str_mv |
Tetragonisca angustula Honey properties Phenolic compounds Glioma cells inhibition DLLME PCA |
topic |
Tetragonisca angustula Honey properties Phenolic compounds Glioma cells inhibition DLLME PCA |
description |
This study aims to analyze Tetragonisca angustula honey from southwestern Bahia for its physicochemical characteristics, phenolic compounds and glioma cell inhibitory effect, in samples from different periods of the year, dry (DP) and rainy (RP) period. The analyses showed that samples obtained in the DP and RP are statistically different for the physicochemical profile (p 0.05). DP honey has a darker color, greater acidity, content of reducing sugars and ash and lower moisture, when compared to RP. The content of total phenolics and flavonoids was determined spectrometrically, using the Folin-Ciocalteu method and reaction with aluminum chloride, respectively, and there was no statistical difference between the samples (p 0.05). For the extraction of phenolic compounds, dispersive liquid-liquid microextraction was used, besides analysis by high-performance liquid chromatography with ultraviolet detection (HPLC-UV), which identified chlorogenic acid and quantified caffeic acid and rutin (1.7723 and 0.9384 ??g 100 mg-1 honey, respectively). Glioma cell inhibition effect lines were observed for DP at concentrations 1000 ng mL-1 of honey. Principal component analysis (PCA) proposes the physicochemical parameters as the main distinguishing factors between the DP and RP samples. DP samples showed similarity for the parameters ash content, acidity and reducing sugars and the samples of the RP had consonance between pH and moisture. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-30T13:44:46Z 2022-11-30T13:44:46Z 2022-07-05 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.21577/0103-5053.20220095 Journal Of The Brazilian Chemical Society. Sao Paulo: Soc Brasileira Quimica, 11 p., 2022. 0103-5053 http://hdl.handle.net/11449/237780 10.21577/0103-5053.20220095 WOS:000823678400001 |
url |
http://dx.doi.org/10.21577/0103-5053.20220095 http://hdl.handle.net/11449/237780 |
identifier_str_mv |
Journal Of The Brazilian Chemical Society. Sao Paulo: Soc Brasileira Quimica, 11 p., 2022. 0103-5053 10.21577/0103-5053.20220095 WOS:000823678400001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal Of The Brazilian Chemical Society |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
11 |
dc.publisher.none.fl_str_mv |
Soc Brasileira Quimica |
publisher.none.fl_str_mv |
Soc Brasileira Quimica |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128866675326976 |