SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5380/avs.v26i4.81431 http://hdl.handle.net/11449/230434 |
Resumo: | Toxoplasmosis is a worldwide distribution zoonosis, caused by the protozoan Toxoplasma gondii (T. gondii). In dogs, ocular toxoplasmosis is considered rare and lesions include keratoconjunctivitis sicca, uveitis, iridocyclitis, ciliary epithelial hyperplasia, retinitis, choroiditis, extraocular myositis, scleritis, episcleritis, optic neuritis, and corneal and conjunctival masses. Thus, the present study aimed to detect IgM and IgG class antibodies against T. gondii in 75 dogs with ophthalmic signs, treated at the Veterinary Hospital of FMVZ Unesp, Botucatu city. Serological results for the detection of IgM and IgG class antibodies were evaluated by the Indirect Immunofluorescence Reaction (RIFI) technique associated with data from a questionnaire regarding the risk factors for toxoplasmosis in the canine species administered to the animal’s guardian on the day of blood collection, regarding the risk factors for toxoplasmosis in canine species. The results were 28/75 (37%) for IgG class antibodies and 34/75 (45%) for IgM class, that is, 37% of the animals were exposed to a pre-infection and 45% were in the acute phase of the disease. 65% of dogs had uveitis as a clinical sign; the others had keratoconjunctiva, ulcers, conjunctivitis, retinochoroiditis, iridocyclitis, retinitis and choroiditis. The importance of observing the ocular changes in patients was noted because it may suggest the presence of an infectious disease. |
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spelling |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONSResposta sorológica das classes IgM e IgG anti-Toxoplasma gondii em cães com alterações ocularesalterações ocularescãodogeye diseasesToxoplasma gondiiToxoplasmosis is a worldwide distribution zoonosis, caused by the protozoan Toxoplasma gondii (T. gondii). In dogs, ocular toxoplasmosis is considered rare and lesions include keratoconjunctivitis sicca, uveitis, iridocyclitis, ciliary epithelial hyperplasia, retinitis, choroiditis, extraocular myositis, scleritis, episcleritis, optic neuritis, and corneal and conjunctival masses. Thus, the present study aimed to detect IgM and IgG class antibodies against T. gondii in 75 dogs with ophthalmic signs, treated at the Veterinary Hospital of FMVZ Unesp, Botucatu city. Serological results for the detection of IgM and IgG class antibodies were evaluated by the Indirect Immunofluorescence Reaction (RIFI) technique associated with data from a questionnaire regarding the risk factors for toxoplasmosis in the canine species administered to the animal’s guardian on the day of blood collection, regarding the risk factors for toxoplasmosis in canine species. The results were 28/75 (37%) for IgG class antibodies and 34/75 (45%) for IgM class, that is, 37% of the animals were exposed to a pre-infection and 45% were in the acute phase of the disease. 65% of dogs had uveitis as a clinical sign; the others had keratoconjunctiva, ulcers, conjunctivitis, retinochoroiditis, iridocyclitis, retinitis and choroiditis. The importance of observing the ocular changes in patients was noted because it may suggest the presence of an infectious disease.Faculdade de Medicina de Botucatu FMB Universidade Estadual Paulista “Júlio de Mesquita Filho”, SPDepartamento de Produção Animal e Medicina Preventiva Serviço de Zoonoses e Saúde Pública Faculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista “Júlio de Mesquita Filho”, São PauloDepartamento de Cirurgia Veterinária e Reprodução Animal Oftalmologia Veterinária Faculdade de Medicina Veterinária e Zootecnia - FMVZ Universidade Estadual Paulista “Júlio de Mesquita Filho”, São PauloFaculdade de Medicina de Botucatu FMB Universidade Estadual Paulista “Júlio de Mesquita Filho”, SPDepartamento de Produção Animal e Medicina Preventiva Serviço de Zoonoses e Saúde Pública Faculdade de Medicina Veterinária e Zootecnia Universidade Estadual Paulista “Júlio de Mesquita Filho”, São PauloDepartamento de Cirurgia Veterinária e Reprodução Animal Oftalmologia Veterinária Faculdade de Medicina Veterinária e Zootecnia - FMVZ Universidade Estadual Paulista “Júlio de Mesquita Filho”, São PauloUniversidade Estadual Paulista (UNESP)Rodrigues, Nássarah Jabur Lot [UNESP]Manzini, Suzane [UNESP]Oliveira, Natalie Newirt [UNESP]e Gava, Mariana Zanchetta [UNESP]Gonçalves, Lenise Garbelotti [UNESP]Hirota, Inajara Nakaruma [UNESP]Ferreira, Annalu Pinton [UNESP]De Sessa, Mariana [UNESP]Ferreira, Mayara Chagas [UNESP]Reiter, Luis Felipe Fernandes [UNESP]Brandão, Claudia Valeria Seullner [UNESP]Langoni, Helio [UNESP]Menozzi, Benedito Donizeti [UNESP]2022-04-29T08:39:55Z2022-04-29T08:39:55Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article48-56http://dx.doi.org/10.5380/avs.v26i4.81431Archives of Veterinary Science, v. 26, n. 4, p. 48-56, 2021.1517-784Xhttp://hdl.handle.net/11449/23043410.5380/avs.v26i4.814312-s2.0-85125058581Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporArchives of Veterinary Scienceinfo:eu-repo/semantics/openAccess2024-09-09T13:01:36Zoai:repositorio.unesp.br:11449/230434Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T13:01:36Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS Resposta sorológica das classes IgM e IgG anti-Toxoplasma gondii em cães com alterações oculares |
title |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
spellingShingle |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS Rodrigues, Nássarah Jabur Lot [UNESP] alterações oculares cão dog eye diseases Toxoplasma gondii |
title_short |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
title_full |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
title_fullStr |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
title_full_unstemmed |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
title_sort |
SEROLOGICAL ANTIBODY RESPONSE OF THE CLASSES IgM AND IgG ANTI-Toxoplasma gondii IN DOGS WITH OCULAR ALTERATIONS |
author |
Rodrigues, Nássarah Jabur Lot [UNESP] |
author_facet |
Rodrigues, Nássarah Jabur Lot [UNESP] Manzini, Suzane [UNESP] Oliveira, Natalie Newirt [UNESP] e Gava, Mariana Zanchetta [UNESP] Gonçalves, Lenise Garbelotti [UNESP] Hirota, Inajara Nakaruma [UNESP] Ferreira, Annalu Pinton [UNESP] De Sessa, Mariana [UNESP] Ferreira, Mayara Chagas [UNESP] Reiter, Luis Felipe Fernandes [UNESP] Brandão, Claudia Valeria Seullner [UNESP] Langoni, Helio [UNESP] Menozzi, Benedito Donizeti [UNESP] |
author_role |
author |
author2 |
Manzini, Suzane [UNESP] Oliveira, Natalie Newirt [UNESP] e Gava, Mariana Zanchetta [UNESP] Gonçalves, Lenise Garbelotti [UNESP] Hirota, Inajara Nakaruma [UNESP] Ferreira, Annalu Pinton [UNESP] De Sessa, Mariana [UNESP] Ferreira, Mayara Chagas [UNESP] Reiter, Luis Felipe Fernandes [UNESP] Brandão, Claudia Valeria Seullner [UNESP] Langoni, Helio [UNESP] Menozzi, Benedito Donizeti [UNESP] |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Rodrigues, Nássarah Jabur Lot [UNESP] Manzini, Suzane [UNESP] Oliveira, Natalie Newirt [UNESP] e Gava, Mariana Zanchetta [UNESP] Gonçalves, Lenise Garbelotti [UNESP] Hirota, Inajara Nakaruma [UNESP] Ferreira, Annalu Pinton [UNESP] De Sessa, Mariana [UNESP] Ferreira, Mayara Chagas [UNESP] Reiter, Luis Felipe Fernandes [UNESP] Brandão, Claudia Valeria Seullner [UNESP] Langoni, Helio [UNESP] Menozzi, Benedito Donizeti [UNESP] |
dc.subject.por.fl_str_mv |
alterações oculares cão dog eye diseases Toxoplasma gondii |
topic |
alterações oculares cão dog eye diseases Toxoplasma gondii |
description |
Toxoplasmosis is a worldwide distribution zoonosis, caused by the protozoan Toxoplasma gondii (T. gondii). In dogs, ocular toxoplasmosis is considered rare and lesions include keratoconjunctivitis sicca, uveitis, iridocyclitis, ciliary epithelial hyperplasia, retinitis, choroiditis, extraocular myositis, scleritis, episcleritis, optic neuritis, and corneal and conjunctival masses. Thus, the present study aimed to detect IgM and IgG class antibodies against T. gondii in 75 dogs with ophthalmic signs, treated at the Veterinary Hospital of FMVZ Unesp, Botucatu city. Serological results for the detection of IgM and IgG class antibodies were evaluated by the Indirect Immunofluorescence Reaction (RIFI) technique associated with data from a questionnaire regarding the risk factors for toxoplasmosis in the canine species administered to the animal’s guardian on the day of blood collection, regarding the risk factors for toxoplasmosis in canine species. The results were 28/75 (37%) for IgG class antibodies and 34/75 (45%) for IgM class, that is, 37% of the animals were exposed to a pre-infection and 45% were in the acute phase of the disease. 65% of dogs had uveitis as a clinical sign; the others had keratoconjunctiva, ulcers, conjunctivitis, retinochoroiditis, iridocyclitis, retinitis and choroiditis. The importance of observing the ocular changes in patients was noted because it may suggest the presence of an infectious disease. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-04-29T08:39:55Z 2022-04-29T08:39:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5380/avs.v26i4.81431 Archives of Veterinary Science, v. 26, n. 4, p. 48-56, 2021. 1517-784X http://hdl.handle.net/11449/230434 10.5380/avs.v26i4.81431 2-s2.0-85125058581 |
url |
http://dx.doi.org/10.5380/avs.v26i4.81431 http://hdl.handle.net/11449/230434 |
identifier_str_mv |
Archives of Veterinary Science, v. 26, n. 4, p. 48-56, 2021. 1517-784X 10.5380/avs.v26i4.81431 2-s2.0-85125058581 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
Archives of Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
48-56 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021339528953856 |