Estudo duplo cego com Isoconazol e Terbinafina tópicos no tratamento de um paciente com Tinea nigra plantaris bilateral e sugestões para novos diagnósticos diferenciais

• Autor(a) principal: Rossetto, André Luiz
• Data de Publicação: 2013
• Outros Autores: Cruz, Rosana Cé Bella, Haddad Júnior, Vidal [UNESP]
• Tipo de documento: Artigo
• Idioma: eng; por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S0036-46652013000200011; http://hdl.handle.net/11449/74741
• topic: Antifungal agents; Dermatomycoses; Mycoses; Tinea; isoconazole; terbinafine; adult; case report; controlled clinical trial; controlled study; differential diagnosis; double blind procedure; drug efficacy; human; hyperpigmentation; insect bite; male; millipede; nonhuman; tinea nigra; tinea nigra plantaris

The authors report a case of bilateral Tinea nigra plantaris treated through a double-blind study with the topical antifungal agents Isoconazole and Terbinafine. The objective of the study was to clinically compare the efficacy of these two topical antifungal agents on days 10, 20 and 30 of the treatment. No significant clinical differences were found, as all the plantar lesions regressed completely by the end of the treatment. Our conclusion was that in the case reported, the topical antifungal agents Isoconazole and Terbinafine demonstrated identical efficacy as a clinical cure. We also suggest the inclusion of injuries caused by arthropods of the Diplopoda Class in the differential diagnosis of Tinea nigra plantaris, due to the persistent acral hyperpigmentation.