Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate

• Autor(a) principal: Delbem, Alberto Carlos Botazzo [UNESP]
• Data de Publicação: 2012
• Outros Autores: Bergamaschi, Mauricio, Rodrigues, Eliana, Sassaki, Kikue Takebayashi [UNESP], de Mello Vieira, Ana Elisa [UNESP], Missel, Emilene Macario Coimbra [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S1678-77572012000100017; http://hdl.handle.net/11449/232060
• topic: Calcium citrate; Dental enamel; Dentifrices; Fluorides; Tooth demineralization

Because of the growing concerns regarding fluoride ingestion by young children and dental fluorosis, it is necessary to develop new dentifrices. Objective: The aim ofthis study was to evaluate the effect of dentifrices with calcium citrate (Cacit) and sodium trimetaphosphate (TMP) on enamel demineralization. Material and Methods: Enamel blocks (n=70), previously selected through surface hardness analysis, were submitted to daily treatment with dentifrices diluted in artificial saliva and to a pH-cycling model. The fluoride concentration in dentifrices was 0, 250, 450, 550, 1,000 and 1,100 μg F/g. Crest™ was used as a positive control (1,100 μg F/g). Cacit (0.25%) and TMP (0.25%) were added to dentifrices with 450 and 1,000 μg F/g. Surface hardness was measured again and integrated loss of subsurface hardness and fluoride concentration in enamel were calculated. Parametric and correlation tests were used to determine difference (p<0.05) and dose-response relationship between treatments. Results: The addition of Cacit and TMP did not provide a higher fluoride concentration in enamel, however it reduced (p<0.05) mineral loss when compared to other dentifrices; the dentifrice with Cacit and TMP and a low fluoride concentration presented similar results when compared to a dentifrice with 1,100 μg F/g (p>0.05). Conclusions: Dentifrices with 450 and 1,000 μg F/g, Cacit and TMP were as effective as a gold standard one.