Epitheliotropic cutaneous T-cell lymphoma associated with melanoma in a dog: case report

• Autor(a) principal: Palumbo, M. I. P. [UNESP]
• Data de Publicação: 2015
• Outros Autores: Rossetto, V. J. V. [UNESP], Torres Neto, R. [UNESP], Brandão, C. V. S. [UNESP], Amorim, R. L. [UNESP], Fabris, V. E. [UNESP], Machado, L. H. A. [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000601073&lng=en&nrm=iso&tlng=en; http://hdl.handle.net/11449/127310
• topic: Oncology; Immunohistochemistry; Malignant skin neoplasms; Oncologia; Imunohistomquímica; Neoplasias cutâneas malignas

Several types of tumors affect dogs' skin. Simultaneously occurring neoplasms with different histological patterns might be rarely present in the same animal. This paper describes the occurrence of epitheliotropic cutaneous T-cell lymphoma and melanoma in a dog. The animal had nodular lesions in the abdominal region and serpiginous plaques on the dorsal region of the trunk. Cytology evidenced malignant fusiform cells from the abdominal lesions as well as few round cells from the dorsal. The histopathological examination of the abdominal lesions showed dermis with polygonal to spindle-shaped neoplastic cells. The lesion of the dorsal region evidenced neoplastic round cells with generally distinct cell borders and a moderate amount of eosinophilic cytoplasm. Abdominal lesions were positive for Melan A. Dorsal and forelimb lesions were positive for CD3. This study reports the occurrence of epitheliotropic cutaneous T-cell lymphoma and malignant melanoma in a crossbred Boxer dog and discusses the importance of performing immunohistochemical profile to confirm the phenotype of the tumor.