Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0074-02762006000300019 http://hdl.handle.net/11449/18120 |
Resumo: | Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features. |
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Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patientsParacoccidioides brasiliensisvirulencehamsterDasypus novemcinctusParacoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features.Departamento de Microbiologia e ImunologiaUnesp Instituto de Biociências Departamento BioestatísticaInstituto Adolfo LutzUnesp Instituto de Biociências Departamento BioestatísticaInstituto Oswaldo Cruz, Ministério da SaúdeDepartamento de Microbiologia e ImunologiaUniversidade Estadual Paulista (Unesp)Instituto Adolfo Lutz (IAL)Macoris, SAGSugizaki, MFPeraçoli, MTSBosco, SMGHebeler-Barbosa, F. [UNESP]Simões, LBTheodoro, RCTrinca, LA [UNESP]Bagagli, Eduardo [UNESP]2014-05-20T13:50:45Z2014-05-20T13:50:45Z2006-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article331-334application/pdfhttp://dx.doi.org/10.1590/S0074-02762006000300019Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 101, n. 3, p. 331-334, 2006.0074-0276http://hdl.handle.net/11449/1812010.1590/S0074-02762006000300019S0074-02762006000300019S0074-02762006000300019.pdf372048936642795533203275704295390000-0002-8003-4109SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMemórias do Instituto Oswaldo Cruz2.8331,172info:eu-repo/semantics/openAccess2024-01-15T06:19:42Zoai:repositorio.unesp.br:11449/18120Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:01:31.673608Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
title |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
spellingShingle |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients Macoris, SAG Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus |
title_short |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
title_full |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
title_fullStr |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
title_full_unstemmed |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
title_sort |
Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients |
author |
Macoris, SAG |
author_facet |
Macoris, SAG Sugizaki, MF Peraçoli, MTS Bosco, SMG Hebeler-Barbosa, F. [UNESP] Simões, LB Theodoro, RC Trinca, LA [UNESP] Bagagli, Eduardo [UNESP] |
author_role |
author |
author2 |
Sugizaki, MF Peraçoli, MTS Bosco, SMG Hebeler-Barbosa, F. [UNESP] Simões, LB Theodoro, RC Trinca, LA [UNESP] Bagagli, Eduardo [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Departamento de Microbiologia e Imunologia Universidade Estadual Paulista (Unesp) Instituto Adolfo Lutz (IAL) |
dc.contributor.author.fl_str_mv |
Macoris, SAG Sugizaki, MF Peraçoli, MTS Bosco, SMG Hebeler-Barbosa, F. [UNESP] Simões, LB Theodoro, RC Trinca, LA [UNESP] Bagagli, Eduardo [UNESP] |
dc.subject.por.fl_str_mv |
Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus |
topic |
Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus |
description |
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-05-01 2014-05-20T13:50:45Z 2014-05-20T13:50:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0074-02762006000300019 Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 101, n. 3, p. 331-334, 2006. 0074-0276 http://hdl.handle.net/11449/18120 10.1590/S0074-02762006000300019 S0074-02762006000300019 S0074-02762006000300019.pdf 3720489366427955 3320327570429539 0000-0002-8003-4109 |
url |
http://dx.doi.org/10.1590/S0074-02762006000300019 http://hdl.handle.net/11449/18120 |
identifier_str_mv |
Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 101, n. 3, p. 331-334, 2006. 0074-0276 10.1590/S0074-02762006000300019 S0074-02762006000300019 S0074-02762006000300019.pdf 3720489366427955 3320327570429539 0000-0002-8003-4109 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz 2.833 1,172 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
331-334 application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129483641716736 |