Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty

Detalhes bibliográficos
Autor(a) principal: Vieira, Narciso Almeida
Data de Publicação: 2013
Outros Autores: Borgo, Hilton Coimbra, Dalben, Gisele Da Silva, Bachega, Maria Irene, Pereira, Paulo Câmara Marques [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1517-83822013000300026
http://hdl.handle.net/11449/227546
Resumo: This study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair. © 2013, Sociedade Brasileira de Microbiologia.
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spelling Evaluation of fecal microorganisms of children with cleft palate before and after palatoplastyCleft palateCleft palate/surgeryEnvironmental microbiologyFecesSurgery/plasticThis study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair. © 2013, Sociedade Brasileira de Microbiologia.Clinical Analysis Laboratory Hospital for Rehabilitation of Craniofacial Anomalies Universidade de São Paulo, Bauru, SPTropical Diseases Department Escola de Medicina Universidade Estadual de São Paulo Júlio de Mesquita Filho, Botucatu, SPTropical Diseases Department Escola de Medicina Universidade Estadual de São Paulo Júlio de Mesquita Filho, Botucatu, SPUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Vieira, Narciso AlmeidaBorgo, Hilton CoimbraDalben, Gisele Da SilvaBachega, Maria IrenePereira, Paulo Câmara Marques [UNESP]2022-04-29T07:13:51Z2022-04-29T07:13:51Z2013-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article835-838http://dx.doi.org/10.1590/S1517-83822013000300026Brazilian Journal of Microbiology, v. 44, n. 3, p. 835-838, 2013.1517-83821678-4405http://hdl.handle.net/11449/22754610.1590/S1517-838220130003000262-s2.0-84893622856Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Microbiologyinfo:eu-repo/semantics/openAccess2024-08-15T15:22:47Zoai:repositorio.unesp.br:11449/227546Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-15T15:22:47Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
title Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
spellingShingle Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
Vieira, Narciso Almeida
Cleft palate
Cleft palate/surgery
Environmental microbiology
Feces
Surgery/plastic
title_short Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
title_full Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
title_fullStr Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
title_full_unstemmed Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
title_sort Evaluation of fecal microorganisms of children with cleft palate before and after palatoplasty
author Vieira, Narciso Almeida
author_facet Vieira, Narciso Almeida
Borgo, Hilton Coimbra
Dalben, Gisele Da Silva
Bachega, Maria Irene
Pereira, Paulo Câmara Marques [UNESP]
author_role author
author2 Borgo, Hilton Coimbra
Dalben, Gisele Da Silva
Bachega, Maria Irene
Pereira, Paulo Câmara Marques [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Vieira, Narciso Almeida
Borgo, Hilton Coimbra
Dalben, Gisele Da Silva
Bachega, Maria Irene
Pereira, Paulo Câmara Marques [UNESP]
dc.subject.por.fl_str_mv Cleft palate
Cleft palate/surgery
Environmental microbiology
Feces
Surgery/plastic
topic Cleft palate
Cleft palate/surgery
Environmental microbiology
Feces
Surgery/plastic
description This study isolated and quantified intestinal bacteria of children with cleft palate before and after palatoplasty. A prospective study was conducted from May 2007 to September 2008 on 18 children with cleft palate, aged one to four years, of both genders, attending a tertiary cleft center in Brazil for palatoplasty, to analyze the effect of surgical palate repair on the concentration of anaerobes Bacteroides sp, Bifidobacterium sp and microaerophiles Lactobacillus sp in feces of infants with cleft palate before and 24 hours after treatment with cefazolin for palatoplasty. There was significant reduction of Lactobacillus sp (p < 0.002), Bacteroides sp (p < 0.001) and Bifidobacterium sp (p = 0.021) after palatoplasty, revealing that surgery and utilization of cefazolin significantly influenced the fecal microbiota comparing collections before and after surgery. However, due to study limitations, it was not possible to conclude that other isolated factors, such as surgical stress, anesthetics and other medications used in palatoplasty might have a significant influence on the microbiota. Considering the important participation of the intestinal microbiota on both local and systemic metabolic and immunological activities of the host, professionals should be attentive to the possible influence of these changes in patients submitted to cleft repair. © 2013, Sociedade Brasileira de Microbiologia.
publishDate 2013
dc.date.none.fl_str_mv 2013-07-01
2022-04-29T07:13:51Z
2022-04-29T07:13:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1517-83822013000300026
Brazilian Journal of Microbiology, v. 44, n. 3, p. 835-838, 2013.
1517-8382
1678-4405
http://hdl.handle.net/11449/227546
10.1590/S1517-83822013000300026
2-s2.0-84893622856
url http://dx.doi.org/10.1590/S1517-83822013000300026
http://hdl.handle.net/11449/227546
identifier_str_mv Brazilian Journal of Microbiology, v. 44, n. 3, p. 835-838, 2013.
1517-8382
1678-4405
10.1590/S1517-83822013000300026
2-s2.0-84893622856
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Microbiology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 835-838
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128138583998464