Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/ece3.6987 http://hdl.handle.net/11449/205525 |
Resumo: | Whole-genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large-scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune-related toll-like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity. |
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Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite loadimmunogenetic diversityinfectious diseasesympatric communitiestoll-like receptorswhole-genome duplicationWhole-genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large-scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune-related toll-like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity.School of Biological Sciences University of East AngliaSchool of Biosciences Cardiff UniversityDepartmento de Morfologia Instituto de Biosiências/UNESPDepartment of Cell and Developmental Biology John Innes CentreFuture Food Beacon of Excellence and the School of Life Sciences University of NottinghamDepartmento de Morfologia Instituto de Biosiências/UNESPUniversity of East AngliaCardiff UniversityUniversidade Estadual Paulista (Unesp)John Innes CentreUniversity of NottinghamBell, Ellen A.Cable, JoOliveira, Claudio [UNESP]Richardson, David S.Yant, LeviTaylor, Martin I.2021-06-25T10:16:55Z2021-06-25T10:16:55Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13949-13956http://dx.doi.org/10.1002/ece3.6987Ecology and Evolution, v. 10, n. 24, p. 13949-13956, 2020.2045-7758http://hdl.handle.net/11449/20552510.1002/ece3.69872-s2.0-85096662547Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengEcology and Evolutioninfo:eu-repo/semantics/openAccess2021-10-23T14:48:14Zoai:repositorio.unesp.br:11449/205525Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T14:48:14Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
title |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
spellingShingle |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load Bell, Ellen A. immunogenetic diversity infectious disease sympatric communities toll-like receptors whole-genome duplication |
title_short |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
title_full |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
title_fullStr |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
title_full_unstemmed |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
title_sort |
Help or hindrance? The evolutionary impact of whole-genome duplication on immunogenetic diversity and parasite load |
author |
Bell, Ellen A. |
author_facet |
Bell, Ellen A. Cable, Jo Oliveira, Claudio [UNESP] Richardson, David S. Yant, Levi Taylor, Martin I. |
author_role |
author |
author2 |
Cable, Jo Oliveira, Claudio [UNESP] Richardson, David S. Yant, Levi Taylor, Martin I. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
University of East Anglia Cardiff University Universidade Estadual Paulista (Unesp) John Innes Centre University of Nottingham |
dc.contributor.author.fl_str_mv |
Bell, Ellen A. Cable, Jo Oliveira, Claudio [UNESP] Richardson, David S. Yant, Levi Taylor, Martin I. |
dc.subject.por.fl_str_mv |
immunogenetic diversity infectious disease sympatric communities toll-like receptors whole-genome duplication |
topic |
immunogenetic diversity infectious disease sympatric communities toll-like receptors whole-genome duplication |
description |
Whole-genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large-scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune-related toll-like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 2021-06-25T10:16:55Z 2021-06-25T10:16:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/ece3.6987 Ecology and Evolution, v. 10, n. 24, p. 13949-13956, 2020. 2045-7758 http://hdl.handle.net/11449/205525 10.1002/ece3.6987 2-s2.0-85096662547 |
url |
http://dx.doi.org/10.1002/ece3.6987 http://hdl.handle.net/11449/205525 |
identifier_str_mv |
Ecology and Evolution, v. 10, n. 24, p. 13949-13956, 2020. 2045-7758 10.1002/ece3.6987 2-s2.0-85096662547 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ecology and Evolution |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
13949-13956 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803649709377585152 |