Efeitos do treinamento físico no comprimento dos sarcômeros e interface músculo-tendão na região cervical em modelo experimental de menopausa

• Autor(a) principal: Jacob, Carolina dos Santos [UNESP]
• Data de Publicação: 2018
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/203480; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2019-05-29/000915859.pdf
• topic: Exercícios físicos; Musculos; Tendões; Menopausa; Envelhecimento; Atrofia muscular; Ovariectomia

Menopause is a physiological process characterized by a hormonal disorders responsible for many adaptations. Another alteration due to aging is muscular atrophy where muscular system undergoes multiple morphological alterations result of sarcopenia. Thus the entire interface area of the myotendinous junction (MTJ) submits to several implications in its morphological and ultrastructural characteristics resulting in drastic changes in the force transmission between the muscle and tendon. The study consisted of describing the structural, ultrastructural and morphometric aspects of the sarcomeres and MTJ of sternomastoid of elderly rats. Female rats with 1 year and 2 months of age were divided into four groups: Sedentary (S); Training (T); Menopause (M) and Training Menopause (TM). The objective of the study was to describe the structural and ultrastructural aspects of the MTJ of the sternomastoid of elderly Wistar rats submitted to the experimental model of menopause and swimming training. And the hypothesis that the sarcomeres have different lengths in the MTJ region. Fourty rats at 1 year and 2 months of age were randomly divided into four groups (n=10): Sedentary (S); Training (T); Menopause (M) and Training Menopause (TM). The M and TM groups were submitted to the surgical procedure of ovariectomy (experimental model of menopause) and the T and TM groups were submitted to daily swimming protocol. The MTJ samples were dissected and analyzed using Light Microscopy and Transmission Electron Microscopy techniques. The lengths of the invaginations and sarcoplasmic evagination, and the distal and proximal sarcomeres were measured using the ImageJ® software, the means and standard deviation were analyzed using Graph Pad Prism 6.0® software with One-Way Variance Analysis and Bonferroni Post-Test. The T group presented an increase in the invagination length of the sarcoplasmic evagination and reduction in the length of the distal and proximal...