Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto

Detalhes bibliográficos
Autor(a) principal: Fernandes, Marco Antonio Rodrigues [UNESP]
Data de Publicação: 2014
Outros Autores: Pasqueta, Jéssica [UNESP], Branco, Isabela Soares Lopes [UNESP], Meira, Luiza Leite de Castro [UNESP], Morelli, Humberto Antonio Soares [UNESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.rbfm.org.br/index.php/rbfm/article/view/242
http://hdl.handle.net/11449/140615
Resumo: The work presents the physical and radiological protection procedures involved in radiotherapy performed in patients during pregnancy that contribute to the security and development of the fetus. We analyzed clinical cases studies with confirmed pregnancy undergoing radiotherapy. The study also analyzed the dosimetry protocols specific to different treatment fields considering the absorbed dose in the region estimated fetal through experimental measurements and computer simulations presented in the literature. It is discussed the concepts of radiation fetuses presented in the Report of the AAPM TG 36 focusing on the influence of the use of appropriate shielding and peripheral dose distribution outside the primary radiation field. Studies show no consensus on the threshold dose for fetal exposure, with values ranging between 2 and 25 cGy, depending on gestational age and position within the abdomen. As recommended by the organs of radiological protection in Brazil, the equivalent dose of radiation to the abdomen of pregnant women occupationally exposed should not exceed 2.0 mSv for the entire period of pregnancy. The measurements show that the main factors contributing to the increase in dose to the fetus are: radiation trail head, scattering from the collimator and dispersion by tissue irradiated region to the region surrounding the fetus. The results of research and clinical situations illustrated in reviewed scientific articles indicate that radiotherapy in pregnant patients is feasible, provided that the dose to the fetus is less than the threshold values, which can be achieved by the use of screens and settings fields Radiation appropriate and properly planned by experts who should simulate physical prior to treatment. The work aims to contribute to subsidize the treatment decision in radiotherapy procedures in pregnant patients pointing out the risks and benefits when the need for treatment.
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spelling Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do fetoRadiation during pregnancy: physical aspects relevant to radiological safety of the fetusRadiotherapyPregnancyRadiation protectionFetusRadioterapiaGravidezProteção radiológicaFetoThe work presents the physical and radiological protection procedures involved in radiotherapy performed in patients during pregnancy that contribute to the security and development of the fetus. We analyzed clinical cases studies with confirmed pregnancy undergoing radiotherapy. The study also analyzed the dosimetry protocols specific to different treatment fields considering the absorbed dose in the region estimated fetal through experimental measurements and computer simulations presented in the literature. It is discussed the concepts of radiation fetuses presented in the Report of the AAPM TG 36 focusing on the influence of the use of appropriate shielding and peripheral dose distribution outside the primary radiation field. Studies show no consensus on the threshold dose for fetal exposure, with values ranging between 2 and 25 cGy, depending on gestational age and position within the abdomen. As recommended by the organs of radiological protection in Brazil, the equivalent dose of radiation to the abdomen of pregnant women occupationally exposed should not exceed 2.0 mSv for the entire period of pregnancy. The measurements show that the main factors contributing to the increase in dose to the fetus are: radiation trail head, scattering from the collimator and dispersion by tissue irradiated region to the region surrounding the fetus. The results of research and clinical situations illustrated in reviewed scientific articles indicate that radiotherapy in pregnant patients is feasible, provided that the dose to the fetus is less than the threshold values, which can be achieved by the use of screens and settings fields Radiation appropriate and properly planned by experts who should simulate physical prior to treatment. The work aims to contribute to subsidize the treatment decision in radiotherapy procedures in pregnant patients pointing out the risks and benefits when the need for treatment.O trabalho apresenta os aspectos físicos e de proteção radiológica envolvidos nos procedimentos de radioterapia realizados em pacientes em período de gravidez que contribuam para a segurança e desenvolvimento do feto. Foram analisados estudos de casos clínicos com gravidez confirmada, submetidos à radioterapia. O trabalho também analisou os protocolos de dosimetria específicos para diferentes campos de tratamento considerando a dose absorvida estimada na região fetal, através de medidas experimentais e simulações computacionais apresentadas na literatura. São discutidos os conceitos de radiação de fetos apresentados no Relatório da AAPM TG 36 enfocando a influencia do uso de blindagem apropriada e a distribuição de dose periférica fora do campo de radiação primário. Os estudos não mostram um consenso quanto à dose limiar para exposição fetal, estando os valores variando entre 2 e 25 cGy, dependendo do período gestacional e da posição no interior do abdômen. Conforme preconizado pelos órgãos de proteção radiológica no Brasil, a dose equivalente de radiação no abdômen da mulher grávida ocupacionalmente exposta não deve exceder a 2,0 mSv durante todo o período de gravidez. As medidas mostram que os principais fatores que contribuem para o aumento de dose no feto são: radiação de fuga do cabeçote, espalhamento pelo colimador e dispersão pelo tecido da região irradiada circunvizinha à região do feto. Os resultados das pesquisas e situações clínicas reais ilustradas nos artigos científicos analisados indicam que a radioterapia em pacientes grávidas é exequível, desde que a dose no feto seja inferior aos limiares indicados, o que pode ser atingido mediante o uso de blindagens e configurações de campos de radiação apropriados e corretamente planejados por físicos especialistas que deverão simular previamente ao tratamento. O trabalho pretende contribuir para subsidiar a decisão terapêutica em procedimentos radioterápicos em pacientes grávidas apontando os riscos e benefícios quando da necessidade do tratamento.Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Doenças Tropicias e Diagnóstico por Imagem, Botucatu, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Instituto de Biociências de Botucatu (IBB), Departamento de Física e Biofísica, Botucatu, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Doenças Tropicias e Diagnóstico por Imagem, Botucatu, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Instituto de Biociências de Botucatu (IBB), Departamento de Física e Biofísica, Botucatu, SP, BrasilUniversidade Estadual Paulista (Unesp)Fernandes, Marco Antonio Rodrigues [UNESP]Pasqueta, Jéssica [UNESP]Branco, Isabela Soares Lopes [UNESP]Meira, Luiza Leite de Castro [UNESP]Morelli, Humberto Antonio Soares [UNESP]2016-07-07T12:34:41Z2016-07-07T12:34:41Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article71-74application/pdfhttp://www.rbfm.org.br/index.php/rbfm/article/view/242Revista Brasileira de Física Médica, v. 7, n. 2, p. 71-74, 2014.1984-9001http://hdl.handle.net/11449/140615ISSN1984-9001-2014-07-02-71-74.pdf23079394253130652307939425313065Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista Brasileira de Física Médicainfo:eu-repo/semantics/openAccess2024-08-15T15:23:28Zoai:repositorio.unesp.br:11449/140615Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-15T15:23:28Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
Radiation during pregnancy: physical aspects relevant to radiological safety of the fetus
title Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
spellingShingle Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
Fernandes, Marco Antonio Rodrigues [UNESP]
Radiotherapy
Pregnancy
Radiation protection
Fetus
Radioterapia
Gravidez
Proteção radiológica
Feto
title_short Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
title_full Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
title_fullStr Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
title_full_unstemmed Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
title_sort Radioterapia durante a gravidez: aspectos físicos relevantes para a segurança radiológica do feto
author Fernandes, Marco Antonio Rodrigues [UNESP]
author_facet Fernandes, Marco Antonio Rodrigues [UNESP]
Pasqueta, Jéssica [UNESP]
Branco, Isabela Soares Lopes [UNESP]
Meira, Luiza Leite de Castro [UNESP]
Morelli, Humberto Antonio Soares [UNESP]
author_role author
author2 Pasqueta, Jéssica [UNESP]
Branco, Isabela Soares Lopes [UNESP]
Meira, Luiza Leite de Castro [UNESP]
Morelli, Humberto Antonio Soares [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Fernandes, Marco Antonio Rodrigues [UNESP]
Pasqueta, Jéssica [UNESP]
Branco, Isabela Soares Lopes [UNESP]
Meira, Luiza Leite de Castro [UNESP]
Morelli, Humberto Antonio Soares [UNESP]
dc.subject.por.fl_str_mv Radiotherapy
Pregnancy
Radiation protection
Fetus
Radioterapia
Gravidez
Proteção radiológica
Feto
topic Radiotherapy
Pregnancy
Radiation protection
Fetus
Radioterapia
Gravidez
Proteção radiológica
Feto
description The work presents the physical and radiological protection procedures involved in radiotherapy performed in patients during pregnancy that contribute to the security and development of the fetus. We analyzed clinical cases studies with confirmed pregnancy undergoing radiotherapy. The study also analyzed the dosimetry protocols specific to different treatment fields considering the absorbed dose in the region estimated fetal through experimental measurements and computer simulations presented in the literature. It is discussed the concepts of radiation fetuses presented in the Report of the AAPM TG 36 focusing on the influence of the use of appropriate shielding and peripheral dose distribution outside the primary radiation field. Studies show no consensus on the threshold dose for fetal exposure, with values ranging between 2 and 25 cGy, depending on gestational age and position within the abdomen. As recommended by the organs of radiological protection in Brazil, the equivalent dose of radiation to the abdomen of pregnant women occupationally exposed should not exceed 2.0 mSv for the entire period of pregnancy. The measurements show that the main factors contributing to the increase in dose to the fetus are: radiation trail head, scattering from the collimator and dispersion by tissue irradiated region to the region surrounding the fetus. The results of research and clinical situations illustrated in reviewed scientific articles indicate that radiotherapy in pregnant patients is feasible, provided that the dose to the fetus is less than the threshold values, which can be achieved by the use of screens and settings fields Radiation appropriate and properly planned by experts who should simulate physical prior to treatment. The work aims to contribute to subsidize the treatment decision in radiotherapy procedures in pregnant patients pointing out the risks and benefits when the need for treatment.
publishDate 2014
dc.date.none.fl_str_mv 2014
2016-07-07T12:34:41Z
2016-07-07T12:34:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.rbfm.org.br/index.php/rbfm/article/view/242
Revista Brasileira de Física Médica, v. 7, n. 2, p. 71-74, 2014.
1984-9001
http://hdl.handle.net/11449/140615
ISSN1984-9001-2014-07-02-71-74.pdf
2307939425313065
2307939425313065
url http://www.rbfm.org.br/index.php/rbfm/article/view/242
http://hdl.handle.net/11449/140615
identifier_str_mv Revista Brasileira de Física Médica, v. 7, n. 2, p. 71-74, 2014.
1984-9001
ISSN1984-9001-2014-07-02-71-74.pdf
2307939425313065
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira de Física Médica
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 71-74
application/pdf
dc.source.none.fl_str_mv Currículo Lattes
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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