Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans

Detalhes bibliográficos
Autor(a) principal: Lara, Bruna Rossini
Data de Publicação: 2019
Outros Autores: Araujo Melo, Milena Barrocali de, Paula, Claudete Rodrigues, Arnoni, Mariana Volpe, Simoes, Cirilo Cesar Naozuka, Nakano, Shirley, Richini-Pereira, Virginia Bodelao, Garces, Hans Garcia [UNESP], Maciel da Silva, Bosco Christiano, Anversa, Lais, Silva, Eriques Gonsalves, Auler, Marcos Ereno, Oliveira dos Santos, Rennan Luiz, Ruiz, Luciana da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1080/00275514.2019.1637645
http://hdl.handle.net/11449/186008
Resumo: This is the first report of the yeast Apiotrichum veenhuisii (formerly Trichosporon veenhuisii) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated from biopsy fragments of disseminated lesions on the skin of a pediatric patient with acute myeloid leukemia. The studied virulence factors evidenced that the strain tested negative for secretion of the enzymes proteinase, phospholipase, and hemolysin. The isolate was characterized as low biofilm producer. Except for amphotericin B and voriconazole, the sample presented high minimum inhibitory concentration values against azole and echinocandins.
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spelling Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humansAntifungalsbiofilmcancerenzymesnosocomial infectionskin lesionTremellomycetesyeastsThis is the first report of the yeast Apiotrichum veenhuisii (formerly Trichosporon veenhuisii) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated from biopsy fragments of disseminated lesions on the skin of a pediatric patient with acute myeloid leukemia. The studied virulence factors evidenced that the strain tested negative for secretion of the enzymes proteinase, phospholipase, and hemolysin. The isolate was characterized as low biofilm producer. Except for amphotericin B and voriconazole, the sample presented high minimum inhibitory concentration values against azole and echinocandins.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Adolfo Lutz Inst, CLR 2, Nucleo Ciencias Biomed, Bauru, SP, BrazilUniv Sao Paulo, Fac Odontol, Sao Paulo, SP, BrazilHosp Infantil Darcy Vargas, Sao Paulo, SP, BrazilUniv Estadual Paulista, Dept Microbiol & Imunol, Botucatu, SP, BrazilUniv Sao Paulo, Fac Med, Sao Paulo, SP, BrazilAdolfo Lutz Inst, Nucleo Ciencias Quim & Bromatol, Bauru, SP, BrazilUniv Estadual Ctr Oeste Parana, Guarapuava, Parana, BrazilUniv Estadual Paulista, Dept Microbiol & Imunol, Botucatu, SP, BrazilTaylor & Francis IncAdolfo Lutz InstUniversidade de São Paulo (USP)Hosp Infantil Darcy VargasUniversidade Estadual Paulista (Unesp)Univ Estadual Ctr Oeste ParanaLara, Bruna RossiniAraujo Melo, Milena Barrocali dePaula, Claudete RodriguesArnoni, Mariana VolpeSimoes, Cirilo Cesar NaozukaNakano, ShirleyRichini-Pereira, Virginia BodelaoGarces, Hans Garcia [UNESP]Maciel da Silva, Bosco ChristianoAnversa, LaisSilva, Eriques GonsalvesAuler, Marcos ErenoOliveira dos Santos, Rennan LuizRuiz, Luciana da Silva2019-10-04T12:40:28Z2019-10-04T12:40:28Z2019-08-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5http://dx.doi.org/10.1080/00275514.2019.1637645Mycologia. Philadelphia: Taylor & Francis Inc, 5 p., 2019.0027-5514http://hdl.handle.net/11449/18600810.1080/00275514.2019.1637645WOS:000480087000001Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMycologiainfo:eu-repo/semantics/openAccess2021-10-23T04:16:17Zoai:repositorio.unesp.br:11449/186008Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:44:42.310460Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
title Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
spellingShingle Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
Lara, Bruna Rossini
Antifungals
biofilm
cancer
enzymes
nosocomial infection
skin lesion
Tremellomycetes
yeasts
title_short Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
title_full Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
title_fullStr Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
title_full_unstemmed Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
title_sort Apiotrichum veenhuisii isolated from a pediatric patient with acute myeloid leukemia: The first case in humans
author Lara, Bruna Rossini
author_facet Lara, Bruna Rossini
Araujo Melo, Milena Barrocali de
Paula, Claudete Rodrigues
Arnoni, Mariana Volpe
Simoes, Cirilo Cesar Naozuka
Nakano, Shirley
Richini-Pereira, Virginia Bodelao
Garces, Hans Garcia [UNESP]
Maciel da Silva, Bosco Christiano
Anversa, Lais
Silva, Eriques Gonsalves
Auler, Marcos Ereno
Oliveira dos Santos, Rennan Luiz
Ruiz, Luciana da Silva
author_role author
author2 Araujo Melo, Milena Barrocali de
Paula, Claudete Rodrigues
Arnoni, Mariana Volpe
Simoes, Cirilo Cesar Naozuka
Nakano, Shirley
Richini-Pereira, Virginia Bodelao
Garces, Hans Garcia [UNESP]
Maciel da Silva, Bosco Christiano
Anversa, Lais
Silva, Eriques Gonsalves
Auler, Marcos Ereno
Oliveira dos Santos, Rennan Luiz
Ruiz, Luciana da Silva
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Adolfo Lutz Inst
Universidade de São Paulo (USP)
Hosp Infantil Darcy Vargas
Universidade Estadual Paulista (Unesp)
Univ Estadual Ctr Oeste Parana
dc.contributor.author.fl_str_mv Lara, Bruna Rossini
Araujo Melo, Milena Barrocali de
Paula, Claudete Rodrigues
Arnoni, Mariana Volpe
Simoes, Cirilo Cesar Naozuka
Nakano, Shirley
Richini-Pereira, Virginia Bodelao
Garces, Hans Garcia [UNESP]
Maciel da Silva, Bosco Christiano
Anversa, Lais
Silva, Eriques Gonsalves
Auler, Marcos Ereno
Oliveira dos Santos, Rennan Luiz
Ruiz, Luciana da Silva
dc.subject.por.fl_str_mv Antifungals
biofilm
cancer
enzymes
nosocomial infection
skin lesion
Tremellomycetes
yeasts
topic Antifungals
biofilm
cancer
enzymes
nosocomial infection
skin lesion
Tremellomycetes
yeasts
description This is the first report of the yeast Apiotrichum veenhuisii (formerly Trichosporon veenhuisii) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated from biopsy fragments of disseminated lesions on the skin of a pediatric patient with acute myeloid leukemia. The studied virulence factors evidenced that the strain tested negative for secretion of the enzymes proteinase, phospholipase, and hemolysin. The isolate was characterized as low biofilm producer. Except for amphotericin B and voriconazole, the sample presented high minimum inhibitory concentration values against azole and echinocandins.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-04T12:40:28Z
2019-10-04T12:40:28Z
2019-08-05
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1080/00275514.2019.1637645
Mycologia. Philadelphia: Taylor & Francis Inc, 5 p., 2019.
0027-5514
http://hdl.handle.net/11449/186008
10.1080/00275514.2019.1637645
WOS:000480087000001
url http://dx.doi.org/10.1080/00275514.2019.1637645
http://hdl.handle.net/11449/186008
identifier_str_mv Mycologia. Philadelphia: Taylor & Francis Inc, 5 p., 2019.
0027-5514
10.1080/00275514.2019.1637645
WOS:000480087000001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Mycologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5
dc.publisher.none.fl_str_mv Taylor & Francis Inc
publisher.none.fl_str_mv Taylor & Francis Inc
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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