In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents

Detalhes bibliográficos
Autor(a) principal: Goto Donato, Tatiani Ayako [UNESP]
Data de Publicação: 2014
Outros Autores: Almeida, Luciano Henrique de [UNESP], Arana-Chavez, Victor Elias, Grandini, Carlos Roberto [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/ma7032183
http://hdl.handle.net/11449/112089
Resumo: Cp-Ti is the most common material used for dental implants, but its elastic modulus is around five times higher than that of bone. Recently, promising alloys that add Nb, Ta, Zr and Mo to Ti have been developed. The mechanical properties of these alloys are directly related to its microstructure and the presence of interstitial elements, such as oxygen, carbon, nitrogen and hydrogen. In this study, the in vitro cytotoxicity of Ti-35Nb-7Zr-5Ta (TNZT) alloys was analyzed in the as-received condition and after being doped with several small quantities of oxygen on a cultured osteogenic cell. The cell's morphology was also examined by scanning electron microscopy (SEM). The TNZT alloy presented no cytotoxic effects on osteoblastic cells in the studied conditions.
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spelling In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen ContentsTi-35Nb-7Zr-5Ta alloyMC3T3-E1 cellsbiocompatibilitycell cultureCp-Ti is the most common material used for dental implants, but its elastic modulus is around five times higher than that of bone. Recently, promising alloys that add Nb, Ta, Zr and Mo to Ti have been developed. The mechanical properties of these alloys are directly related to its microstructure and the presence of interstitial elements, such as oxygen, carbon, nitrogen and hydrogen. In this study, the in vitro cytotoxicity of Ti-35Nb-7Zr-5Ta (TNZT) alloys was analyzed in the as-received condition and after being doped with several small quantities of oxygen on a cultured osteogenic cell. The cell's morphology was also examined by scanning electron microscopy (SEM). The TNZT alloy presented no cytotoxic effects on osteoblastic cells in the studied conditions.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)UNESP Univ Estadual Paulista, Lab Anelasticidade & Biomat, BR-17033360 Bauru, SP, BrazilUniv Sao Paulo, Fac Odontol, Dept Biomat & Biol Oral, BR-05508900 Sao Paulo, BrazilUNESP Univ Estadual Paulista, Lab Anelasticidade & Biomat, BR-17033360 Bauru, SP, BrazilMdpi AgUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Goto Donato, Tatiani Ayako [UNESP]Almeida, Luciano Henrique de [UNESP]Arana-Chavez, Victor EliasGrandini, Carlos Roberto [UNESP]2014-12-03T13:09:13Z2014-12-03T13:09:13Z2014-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2183-2193application/pdfhttp://dx.doi.org/10.3390/ma7032183Materials. Basel: Mdpi Ag, v. 7, n. 3, p. 2183-2193, 2014.1996-1944http://hdl.handle.net/11449/11208910.3390/ma7032183WOS:000336089500038WOS000336089500038.pdf29499838674183380000-0002-3336-309XWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterials2.4670,732info:eu-repo/semantics/openAccess2024-04-25T17:39:30Zoai:repositorio.unesp.br:11449/112089Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:20:19.683369Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
title In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
spellingShingle In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
Goto Donato, Tatiani Ayako [UNESP]
Ti-35Nb-7Zr-5Ta alloy
MC3T3-E1 cells
biocompatibility
cell culture
title_short In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
title_full In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
title_fullStr In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
title_full_unstemmed In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
title_sort In Vitro Cytotoxicity of a Ti-35Nb-7Zr-5Ta Alloy Doped with Different Oxygen Contents
author Goto Donato, Tatiani Ayako [UNESP]
author_facet Goto Donato, Tatiani Ayako [UNESP]
Almeida, Luciano Henrique de [UNESP]
Arana-Chavez, Victor Elias
Grandini, Carlos Roberto [UNESP]
author_role author
author2 Almeida, Luciano Henrique de [UNESP]
Arana-Chavez, Victor Elias
Grandini, Carlos Roberto [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Goto Donato, Tatiani Ayako [UNESP]
Almeida, Luciano Henrique de [UNESP]
Arana-Chavez, Victor Elias
Grandini, Carlos Roberto [UNESP]
dc.subject.por.fl_str_mv Ti-35Nb-7Zr-5Ta alloy
MC3T3-E1 cells
biocompatibility
cell culture
topic Ti-35Nb-7Zr-5Ta alloy
MC3T3-E1 cells
biocompatibility
cell culture
description Cp-Ti is the most common material used for dental implants, but its elastic modulus is around five times higher than that of bone. Recently, promising alloys that add Nb, Ta, Zr and Mo to Ti have been developed. The mechanical properties of these alloys are directly related to its microstructure and the presence of interstitial elements, such as oxygen, carbon, nitrogen and hydrogen. In this study, the in vitro cytotoxicity of Ti-35Nb-7Zr-5Ta (TNZT) alloys was analyzed in the as-received condition and after being doped with several small quantities of oxygen on a cultured osteogenic cell. The cell's morphology was also examined by scanning electron microscopy (SEM). The TNZT alloy presented no cytotoxic effects on osteoblastic cells in the studied conditions.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-03T13:09:13Z
2014-12-03T13:09:13Z
2014-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/ma7032183
Materials. Basel: Mdpi Ag, v. 7, n. 3, p. 2183-2193, 2014.
1996-1944
http://hdl.handle.net/11449/112089
10.3390/ma7032183
WOS:000336089500038
WOS000336089500038.pdf
2949983867418338
0000-0002-3336-309X
url http://dx.doi.org/10.3390/ma7032183
http://hdl.handle.net/11449/112089
identifier_str_mv Materials. Basel: Mdpi Ag, v. 7, n. 3, p. 2183-2193, 2014.
1996-1944
10.3390/ma7032183
WOS:000336089500038
WOS000336089500038.pdf
2949983867418338
0000-0002-3336-309X
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials
2.467
0,732
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 2183-2193
application/pdf
dc.publisher.none.fl_str_mv Mdpi Ag
publisher.none.fl_str_mv Mdpi Ag
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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