Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-91992012000200015 http://hdl.handle.net/11449/226905 |
Resumo: | Yeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were: antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were: C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality rate (75%), followed by C. tropicalis (57.1%) and C. albicans (54.5%). The elevated mortality rate found in this study indicates that preventive measures against candidemia must be emphasized in hospitals. © CEVAP 2012. |
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Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year periodAssociated factorsCandida albicansCandidemiaMortalityYeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were: antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were: C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality rate (75%), followed by C. tropicalis (57.1%) and C. albicans (54.5%). The elevated mortality rate found in this study indicates that preventive measures against candidemia must be emphasized in hospitals. © CEVAP 2012.Department of Internal Medicine Botucatu Medical School São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo StateDepartment of Microbiology and Immunology Botucatu Biosciences Institute São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo StateDepartment of Internal Medicine Botucatu Medical School São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo StateDepartment of Microbiology and Immunology Botucatu Biosciences Institute São Paulo State University (UNESP - Univ Estadual Paulista), Botucatu, São Paulo StateUniversidade Estadual Paulista (UNESP)Mondelli, Alessandro Lia [UNESP]Niéro-Melo, L. [UNESP]Bagagli, E. [UNESP]Camargo, C. H. [UNESP]Bruder-Nascimento, A. [UNESP]Sugizaki, M. F. [UNESP]Carneiro, M. V. [UNESP]Villas Boas, P. J.F. [UNESP]2022-04-29T04:22:50Z2022-04-29T04:22:50Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article244-252http://dx.doi.org/10.1590/S1678-91992012000200015Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 18, n. 2, p. 244-252, 2012.1678-91991678-9180http://hdl.handle.net/11449/22690510.1590/S1678-919920120002000152-s2.0-84863990819Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseasesinfo:eu-repo/semantics/openAccess2024-08-14T17:23:00Zoai:repositorio.unesp.br:11449/226905Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:23Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
title |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
spellingShingle |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period Mondelli, Alessandro Lia [UNESP] Associated factors Candida albicans Candidemia Mortality |
title_short |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
title_full |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
title_fullStr |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
title_full_unstemmed |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
title_sort |
Candidemia in a Brazilian tertiary hospital: Microbiological and clinical features over a six-year period |
author |
Mondelli, Alessandro Lia [UNESP] |
author_facet |
Mondelli, Alessandro Lia [UNESP] Niéro-Melo, L. [UNESP] Bagagli, E. [UNESP] Camargo, C. H. [UNESP] Bruder-Nascimento, A. [UNESP] Sugizaki, M. F. [UNESP] Carneiro, M. V. [UNESP] Villas Boas, P. J.F. [UNESP] |
author_role |
author |
author2 |
Niéro-Melo, L. [UNESP] Bagagli, E. [UNESP] Camargo, C. H. [UNESP] Bruder-Nascimento, A. [UNESP] Sugizaki, M. F. [UNESP] Carneiro, M. V. [UNESP] Villas Boas, P. J.F. [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Mondelli, Alessandro Lia [UNESP] Niéro-Melo, L. [UNESP] Bagagli, E. [UNESP] Camargo, C. H. [UNESP] Bruder-Nascimento, A. [UNESP] Sugizaki, M. F. [UNESP] Carneiro, M. V. [UNESP] Villas Boas, P. J.F. [UNESP] |
dc.subject.por.fl_str_mv |
Associated factors Candida albicans Candidemia Mortality |
topic |
Associated factors Candida albicans Candidemia Mortality |
description |
Yeasts are becoming a common cause of nosocomial fungal infections in immunocompromised patients. Such infections often develop into sepsis with high mortality rates. The aim of this study was to evaluate some of the numerous factors associated with the development of candidemia. Medical records were retrospectively analyzed of 98 Candida spp. patients. Results showed that the most prevalent risk factors for developing candidemia were: antibiotics and antifungal agents (93.9% and 79.6%, respectively); the use of central venous catheter (93.9%); mechanical ventilation (73.5%); and parenteral nutrition (60.2%). The main species of Candida found were: C. parapsilosis (37.76%), C. albicans (33.67%); and others (28.57%). C. glabrata showed the highest mortality rate (75%), followed by C. tropicalis (57.1%) and C. albicans (54.5%). The elevated mortality rate found in this study indicates that preventive measures against candidemia must be emphasized in hospitals. © CEVAP 2012. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-01-01 2022-04-29T04:22:50Z 2022-04-29T04:22:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-91992012000200015 Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 18, n. 2, p. 244-252, 2012. 1678-9199 1678-9180 http://hdl.handle.net/11449/226905 10.1590/S1678-91992012000200015 2-s2.0-84863990819 |
url |
http://dx.doi.org/10.1590/S1678-91992012000200015 http://hdl.handle.net/11449/226905 |
identifier_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 18, n. 2, p. 244-252, 2012. 1678-9199 1678-9180 10.1590/S1678-91992012000200015 2-s2.0-84863990819 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
244-252 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128146337169408 |