Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/ma16051970 http://hdl.handle.net/11449/249758 |
Resumo: | This study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance. |
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Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloybiomaterialscell culturecorrosion behaviormechanical propertiesTi-Ta-Nb-SnThis study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance.School of Engineering São Paulo State University (Unesp)Department of Materials and Technology School of Engineering and Sciences São Paulo State University (Unesp)School of Advanced Materials Discovery Colorado State University (CSU)Department of Chemistry and Energy School of Engineering and Sciences São Paulo State University (Unesp)Department of Mechanical Engineering School of Biomedical Engineering Colorado State University (CSU)School of Engineering São Paulo State University (Unesp)Department of Materials and Technology School of Engineering and Sciences São Paulo State University (Unesp)Department of Chemistry and Energy School of Engineering and Sciences São Paulo State University (Unesp)Universidade Estadual Paulista (UNESP)Colorado State University (CSU)Silva, Kerolene Barboza da [UNESP]Carobolante, João Pedro Aquiles [UNESP]Rajan, S. Sudhagara [UNESP]Júnior, Celso Bortolini [UNESP]Sabino, Roberta MaiaSeixas, Maurício Rangel [UNESP]Nakazato, Roberto Zenhei [UNESP]Popat, Ketul C.Claro, Ana Paula Rosifini Alves [UNESP]2023-07-29T16:08:23Z2023-07-29T16:08:23Z2023-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ma16051970Materials, v. 16, n. 5, 2023.1996-1944http://hdl.handle.net/11449/24975810.3390/ma160519702-s2.0-85149894615Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterialsinfo:eu-repo/semantics/openAccess2024-07-02T15:03:45Zoai:repositorio.unesp.br:11449/249758Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:35:56.650845Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
title |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
spellingShingle |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy Silva, Kerolene Barboza da [UNESP] biomaterials cell culture corrosion behavior mechanical properties Ti-Ta-Nb-Sn |
title_short |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
title_full |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
title_fullStr |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
title_full_unstemmed |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
title_sort |
Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy |
author |
Silva, Kerolene Barboza da [UNESP] |
author_facet |
Silva, Kerolene Barboza da [UNESP] Carobolante, João Pedro Aquiles [UNESP] Rajan, S. Sudhagara [UNESP] Júnior, Celso Bortolini [UNESP] Sabino, Roberta Maia Seixas, Maurício Rangel [UNESP] Nakazato, Roberto Zenhei [UNESP] Popat, Ketul C. Claro, Ana Paula Rosifini Alves [UNESP] |
author_role |
author |
author2 |
Carobolante, João Pedro Aquiles [UNESP] Rajan, S. Sudhagara [UNESP] Júnior, Celso Bortolini [UNESP] Sabino, Roberta Maia Seixas, Maurício Rangel [UNESP] Nakazato, Roberto Zenhei [UNESP] Popat, Ketul C. Claro, Ana Paula Rosifini Alves [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Colorado State University (CSU) |
dc.contributor.author.fl_str_mv |
Silva, Kerolene Barboza da [UNESP] Carobolante, João Pedro Aquiles [UNESP] Rajan, S. Sudhagara [UNESP] Júnior, Celso Bortolini [UNESP] Sabino, Roberta Maia Seixas, Maurício Rangel [UNESP] Nakazato, Roberto Zenhei [UNESP] Popat, Ketul C. Claro, Ana Paula Rosifini Alves [UNESP] |
dc.subject.por.fl_str_mv |
biomaterials cell culture corrosion behavior mechanical properties Ti-Ta-Nb-Sn |
topic |
biomaterials cell culture corrosion behavior mechanical properties Ti-Ta-Nb-Sn |
description |
This study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T16:08:23Z 2023-07-29T16:08:23Z 2023-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/ma16051970 Materials, v. 16, n. 5, 2023. 1996-1944 http://hdl.handle.net/11449/249758 10.3390/ma16051970 2-s2.0-85149894615 |
url |
http://dx.doi.org/10.3390/ma16051970 http://hdl.handle.net/11449/249758 |
identifier_str_mv |
Materials, v. 16, n. 5, 2023. 1996-1944 10.3390/ma16051970 2-s2.0-85149894615 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128676064133120 |