Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy

Detalhes bibliográficos
Autor(a) principal: Silva, Kerolene Barboza da [UNESP]
Data de Publicação: 2023
Outros Autores: Carobolante, João Pedro Aquiles [UNESP], Rajan, S. Sudhagara [UNESP], Júnior, Celso Bortolini [UNESP], Sabino, Roberta Maia, Seixas, Maurício Rangel [UNESP], Nakazato, Roberto Zenhei [UNESP], Popat, Ketul C., Claro, Ana Paula Rosifini Alves [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/ma16051970
http://hdl.handle.net/11449/249758
Resumo: This study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance.
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spelling Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloybiomaterialscell culturecorrosion behaviormechanical propertiesTi-Ta-Nb-SnThis study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance.School of Engineering São Paulo State University (Unesp)Department of Materials and Technology School of Engineering and Sciences São Paulo State University (Unesp)School of Advanced Materials Discovery Colorado State University (CSU)Department of Chemistry and Energy School of Engineering and Sciences São Paulo State University (Unesp)Department of Mechanical Engineering School of Biomedical Engineering Colorado State University (CSU)School of Engineering São Paulo State University (Unesp)Department of Materials and Technology School of Engineering and Sciences São Paulo State University (Unesp)Department of Chemistry and Energy School of Engineering and Sciences São Paulo State University (Unesp)Universidade Estadual Paulista (UNESP)Colorado State University (CSU)Silva, Kerolene Barboza da [UNESP]Carobolante, João Pedro Aquiles [UNESP]Rajan, S. Sudhagara [UNESP]Júnior, Celso Bortolini [UNESP]Sabino, Roberta MaiaSeixas, Maurício Rangel [UNESP]Nakazato, Roberto Zenhei [UNESP]Popat, Ketul C.Claro, Ana Paula Rosifini Alves [UNESP]2023-07-29T16:08:23Z2023-07-29T16:08:23Z2023-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ma16051970Materials, v. 16, n. 5, 2023.1996-1944http://hdl.handle.net/11449/24975810.3390/ma160519702-s2.0-85149894615Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterialsinfo:eu-repo/semantics/openAccess2024-07-02T15:03:45Zoai:repositorio.unesp.br:11449/249758Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:35:56.650845Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
title Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
spellingShingle Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
Silva, Kerolene Barboza da [UNESP]
biomaterials
cell culture
corrosion behavior
mechanical properties
Ti-Ta-Nb-Sn
title_short Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
title_full Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
title_fullStr Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
title_full_unstemmed Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
title_sort Mechanical Properties, Corrosion Behavior, and In Vitro Cell Studies of the New Ti-25Ta-25Nb-5Sn Alloy
author Silva, Kerolene Barboza da [UNESP]
author_facet Silva, Kerolene Barboza da [UNESP]
Carobolante, João Pedro Aquiles [UNESP]
Rajan, S. Sudhagara [UNESP]
Júnior, Celso Bortolini [UNESP]
Sabino, Roberta Maia
Seixas, Maurício Rangel [UNESP]
Nakazato, Roberto Zenhei [UNESP]
Popat, Ketul C.
Claro, Ana Paula Rosifini Alves [UNESP]
author_role author
author2 Carobolante, João Pedro Aquiles [UNESP]
Rajan, S. Sudhagara [UNESP]
Júnior, Celso Bortolini [UNESP]
Sabino, Roberta Maia
Seixas, Maurício Rangel [UNESP]
Nakazato, Roberto Zenhei [UNESP]
Popat, Ketul C.
Claro, Ana Paula Rosifini Alves [UNESP]
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Colorado State University (CSU)
dc.contributor.author.fl_str_mv Silva, Kerolene Barboza da [UNESP]
Carobolante, João Pedro Aquiles [UNESP]
Rajan, S. Sudhagara [UNESP]
Júnior, Celso Bortolini [UNESP]
Sabino, Roberta Maia
Seixas, Maurício Rangel [UNESP]
Nakazato, Roberto Zenhei [UNESP]
Popat, Ketul C.
Claro, Ana Paula Rosifini Alves [UNESP]
dc.subject.por.fl_str_mv biomaterials
cell culture
corrosion behavior
mechanical properties
Ti-Ta-Nb-Sn
topic biomaterials
cell culture
corrosion behavior
mechanical properties
Ti-Ta-Nb-Sn
description This study aims to characterize a new Ti-25Ta-25Nb-5Sn alloy for biomedical application. Microstructure, phase formation, mechanical and corrosion properties, along with the cell culture study of the Ti-25Ta-25Nb alloy with Sn content 5 mass% are presented in this article. The experimental alloy was processed in an arc melting furnace, cold worked, and heat treated. For characterization, optical microscopy, X-ray diffraction, microhardness, and Young’s modulus measurements were employed. Corrosion behavior was also evaluated using open-circuit potential (OCP) and potentiodynamic polarization. In vitro studies with human ADSCs were performed to investigate cell viability, adhesion, proliferation, and differentiation. Comparison among the mechanical properties observed in other metal alloy systems, including CP Ti, Ti-25Ta-25Nb, and Ti-25Ta-25-Nb-3Sn showed an increase in microhardness and a decrease in the Young’s modulus when compared to CP Ti. The potentiodynamic polarization tests indicated that the corrosion resistance of the Ti-25Ta-25Nb-5Sn alloy was similar to CP Ti and the experiments in vitro demonstrated great interactions between the alloy surface and cells in terms of adhesion, proliferation, and differentiation. Therefore, this alloy presents potential for biomedical applications with properties required for good performance.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-29T16:08:23Z
2023-07-29T16:08:23Z
2023-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/ma16051970
Materials, v. 16, n. 5, 2023.
1996-1944
http://hdl.handle.net/11449/249758
10.3390/ma16051970
2-s2.0-85149894615
url http://dx.doi.org/10.3390/ma16051970
http://hdl.handle.net/11449/249758
identifier_str_mv Materials, v. 16, n. 5, 2023.
1996-1944
10.3390/ma16051970
2-s2.0-85149894615
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Materials
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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