Complete 1H and 13C NMR structural assignments for five semi-synthetic eremantholides

• Autor(a) principal: Sass, Daiane C. [UNESP]
• Data de Publicação: 2021
• Outros Autores: Ferreira, Alexsandro E., Vieira, Gabrielle [UNESP], Rezende, Ana Laura M., Kovatch, Pedro Y., Palaretti, Vinícius, Constantino, Mauricio G., Heleno, Vladimir C.G.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1016/j.molstruc.2021.131004; http://hdl.handle.net/11449/229126
• topic: Eremantholides; Multiplicities clarifying; NMR data; Sesquiterpene lactones

Five eremantholides were prepared from natural furanoheliangolides by reductions with Stryker's reagent, in previous works. We thus decided to perform a detailed and complete assignment of all 1H and 13C NMR data for those compounds. Through NMR experiments such as 1H NMR, 13C {1H} NMR, gCOSY, gHMQC, gHMBC, J-resolved, among others, it was achieved an unequivocal assignment of 1H and 13C NMR data for all studied substances, with measurement of all H/H homonuclear coupling constants and the clarification of all hydrogen signals multiplicities. Those data were not completely available yet in the literature.