Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.diagmicrobio.2016.01.014 http://hdl.handle.net/11449/177862 |
Resumo: | The aim of this study was to evaluate the production of virulence factors in Candida isolates from the oral cavities of 50 patients with different degrees of denture stomatitis (DS, type I, II and III) and 50 individuals without signs of DS. We evaluated the enzymatic and hemolytic activities, the biofilm formation, and the cell surface hydrophobicity (CSH) in all isolates. Germ tube (GT) production was also evaluated in Candida albicans and Candida dubliniensis isolates. In C. albicans and C. dubliniensis the secretion of hemolysin and GT production was significantly different between isolates from patients with DS and individuals without DS. No significant difference was observed in the production of virulence factors by Candida glabrata isolates. Candida isolates expressed a wide range of virulence factors. However, in the majority of isolates from the type III lesions, the production of the virulence factors was higher than for the other groups. |
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Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individualsCandidaDenture stomatitisVirulence factorsThe aim of this study was to evaluate the production of virulence factors in Candida isolates from the oral cavities of 50 patients with different degrees of denture stomatitis (DS, type I, II and III) and 50 individuals without signs of DS. We evaluated the enzymatic and hemolytic activities, the biofilm formation, and the cell surface hydrophobicity (CSH) in all isolates. Germ tube (GT) production was also evaluated in Candida albicans and Candida dubliniensis isolates. In C. albicans and C. dubliniensis the secretion of hemolysin and GT production was significantly different between isolates from patients with DS and individuals without DS. No significant difference was observed in the production of virulence factors by Candida glabrata isolates. Candida isolates expressed a wide range of virulence factors. However, in the majority of isolates from the type III lesions, the production of the virulence factors was higher than for the other groups.Institute of Science and Technology UNESP Univ Estadual Paulista Francisco José Longo 777 São DimasInstitute of Science and Technology UNESP Univ Estadual Paulista Francisco José Longo 777 São DimasUniversidade Estadual Paulista (Unesp)Pereira, Cristiane Aparecida [UNESP]Domingues, Nádia [UNESP]Araújo, Maria Izabel Daniel Santos Alves [UNESP]Junqueira, Juliana Campos [UNESP]Back-Brito, Graziella Nuernberg [UNESP]Jorge, Antonio Olavo Cardoso [UNESP]2018-12-11T17:27:28Z2018-12-11T17:27:28Z2016-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article66-72http://dx.doi.org/10.1016/j.diagmicrobio.2016.01.014Diagnostic Microbiology and Infectious Disease, v. 85, n. 1, p. 66-72, 2016.1879-00700732-8893http://hdl.handle.net/11449/17786210.1016/j.diagmicrobio.2016.01.0142-s2.0-84960156357Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDiagnostic Microbiology and Infectious Disease1,157info:eu-repo/semantics/openAccess2021-10-23T15:48:23Zoai:repositorio.unesp.br:11449/177862Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T15:48:23Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
title |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
spellingShingle |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals Pereira, Cristiane Aparecida [UNESP] Candida Denture stomatitis Virulence factors |
title_short |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
title_full |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
title_fullStr |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
title_full_unstemmed |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
title_sort |
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals |
author |
Pereira, Cristiane Aparecida [UNESP] |
author_facet |
Pereira, Cristiane Aparecida [UNESP] Domingues, Nádia [UNESP] Araújo, Maria Izabel Daniel Santos Alves [UNESP] Junqueira, Juliana Campos [UNESP] Back-Brito, Graziella Nuernberg [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
author_role |
author |
author2 |
Domingues, Nádia [UNESP] Araújo, Maria Izabel Daniel Santos Alves [UNESP] Junqueira, Juliana Campos [UNESP] Back-Brito, Graziella Nuernberg [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Pereira, Cristiane Aparecida [UNESP] Domingues, Nádia [UNESP] Araújo, Maria Izabel Daniel Santos Alves [UNESP] Junqueira, Juliana Campos [UNESP] Back-Brito, Graziella Nuernberg [UNESP] Jorge, Antonio Olavo Cardoso [UNESP] |
dc.subject.por.fl_str_mv |
Candida Denture stomatitis Virulence factors |
topic |
Candida Denture stomatitis Virulence factors |
description |
The aim of this study was to evaluate the production of virulence factors in Candida isolates from the oral cavities of 50 patients with different degrees of denture stomatitis (DS, type I, II and III) and 50 individuals without signs of DS. We evaluated the enzymatic and hemolytic activities, the biofilm formation, and the cell surface hydrophobicity (CSH) in all isolates. Germ tube (GT) production was also evaluated in Candida albicans and Candida dubliniensis isolates. In C. albicans and C. dubliniensis the secretion of hemolysin and GT production was significantly different between isolates from patients with DS and individuals without DS. No significant difference was observed in the production of virulence factors by Candida glabrata isolates. Candida isolates expressed a wide range of virulence factors. However, in the majority of isolates from the type III lesions, the production of the virulence factors was higher than for the other groups. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-05-01 2018-12-11T17:27:28Z 2018-12-11T17:27:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.diagmicrobio.2016.01.014 Diagnostic Microbiology and Infectious Disease, v. 85, n. 1, p. 66-72, 2016. 1879-0070 0732-8893 http://hdl.handle.net/11449/177862 10.1016/j.diagmicrobio.2016.01.014 2-s2.0-84960156357 |
url |
http://dx.doi.org/10.1016/j.diagmicrobio.2016.01.014 http://hdl.handle.net/11449/177862 |
identifier_str_mv |
Diagnostic Microbiology and Infectious Disease, v. 85, n. 1, p. 66-72, 2016. 1879-0070 0732-8893 10.1016/j.diagmicrobio.2016.01.014 2-s2.0-84960156357 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Diagnostic Microbiology and Infectious Disease 1,157 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
66-72 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965290229923840 |