Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/ma13235494 http://hdl.handle.net/11449/205558 |
Resumo: | Luminescent organic-inorganic hybrids containing lanthanides (Ln3+) have been prominent for applications such as luminescent bio-probes in biological assays. In this sense, a luminescent hybrid based on dense silica (SiO2) nanospheres decorated with Eu3+ β–diketonate complexes using dibenzoylmethane (Hdbm) as a luminescent antenna was developed by using a hierarchical organization in four steps: (i) anchoring of 3-aminopropyltriethoxysilane (APTES) organosilane on the SiO2 surface, (ii) formation of a carboxylic acid ligand, (iii) coordination of Eu3+ to the carboxylate groups and (iv) coordination of dbm− to Eu3+. The hybrid structure was elucidated through the correlation of thermogravimetry, silicon nuclear magnetic resonance and photoluminescence. Results indicate that the carboxylic acid-Eu3+-dbm hybrid was formed on the surface of the particles with no detectable changes on their size or shape after all the four steps (average size of 32 ± 7 nm). A surface charge of −27.8 mV was achieved for the hybrid, assuring a stable suspension in aqueous media. The Eu3+ complex provides intense red luminescence, characteristic of Eu3+ 5D0→7FJ electronic transitions, with an intrinsic emission quantum yield of 38%, even in an aqueous suspension. Therefore, the correlation of luminescence, structure, particle morphology and fluorescence microscopy images make the hybrid promising for application in bioimaging. |
id |
UNSP_e59a411584f7ef46be07896517a48336 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/205558 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker applicationBioimagingFunctionalizationLanthanideLuminescent materialSiO2β–diketoneLuminescent organic-inorganic hybrids containing lanthanides (Ln3+) have been prominent for applications such as luminescent bio-probes in biological assays. In this sense, a luminescent hybrid based on dense silica (SiO2) nanospheres decorated with Eu3+ β–diketonate complexes using dibenzoylmethane (Hdbm) as a luminescent antenna was developed by using a hierarchical organization in four steps: (i) anchoring of 3-aminopropyltriethoxysilane (APTES) organosilane on the SiO2 surface, (ii) formation of a carboxylic acid ligand, (iii) coordination of Eu3+ to the carboxylate groups and (iv) coordination of dbm− to Eu3+. The hybrid structure was elucidated through the correlation of thermogravimetry, silicon nuclear magnetic resonance and photoluminescence. Results indicate that the carboxylic acid-Eu3+-dbm hybrid was formed on the surface of the particles with no detectable changes on their size or shape after all the four steps (average size of 32 ± 7 nm). A surface charge of −27.8 mV was achieved for the hybrid, assuring a stable suspension in aqueous media. The Eu3+ complex provides intense red luminescence, characteristic of Eu3+ 5D0→7FJ electronic transitions, with an intrinsic emission quantum yield of 38%, even in an aqueous suspension. Therefore, the correlation of luminescence, structure, particle morphology and fluorescence microscopy images make the hybrid promising for application in bioimaging.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)School of Technology and Sciences São Paulo State University (Unesp)Institute of Biosciences Humanities and Exact Sciences São Paulo State University (Unesp)Institute of Chemistry São Paulo State University (Unesp)School of Technology and Sciences São Paulo State University (Unesp)Institute of Biosciences Humanities and Exact Sciences São Paulo State University (Unesp)Institute of Chemistry São Paulo State University (Unesp)FAPESP: 2014/04907-3FAPESP: 2019/26103-7FAPESP: 2020/14749-7CAPES: 307385/2015-9CNPq: 307385/2015-9Universidade Estadual Paulista (Unesp)Santos, João A. O. [UNESP]Mutti, Alessandra M. G. [UNESP]Bispo-Jr, Airton G. [UNESP]Pires, Ana M. [UNESP]Lima, Sergio A. M. [UNESP]2021-06-25T10:17:27Z2021-06-25T10:17:27Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-17http://dx.doi.org/10.3390/ma13235494Materials, v. 13, n. 23, p. 1-17, 2020.1996-1944http://hdl.handle.net/11449/20555810.3390/ma132354942-s2.0-85097026347Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMaterialsinfo:eu-repo/semantics/openAccess2021-10-23T14:54:00Zoai:repositorio.unesp.br:11449/205558Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:08:22.354917Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
title |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
spellingShingle |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application Santos, João A. O. [UNESP] Bioimaging Functionalization Lanthanide Luminescent material SiO2 β–diketone |
title_short |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
title_full |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
title_fullStr |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
title_full_unstemmed |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
title_sort |
Red-emitting hybrid based on eu3+-dbm complex anchored on silica nanoparticles surface by carboxylic acid for biomarker application |
author |
Santos, João A. O. [UNESP] |
author_facet |
Santos, João A. O. [UNESP] Mutti, Alessandra M. G. [UNESP] Bispo-Jr, Airton G. [UNESP] Pires, Ana M. [UNESP] Lima, Sergio A. M. [UNESP] |
author_role |
author |
author2 |
Mutti, Alessandra M. G. [UNESP] Bispo-Jr, Airton G. [UNESP] Pires, Ana M. [UNESP] Lima, Sergio A. M. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Santos, João A. O. [UNESP] Mutti, Alessandra M. G. [UNESP] Bispo-Jr, Airton G. [UNESP] Pires, Ana M. [UNESP] Lima, Sergio A. M. [UNESP] |
dc.subject.por.fl_str_mv |
Bioimaging Functionalization Lanthanide Luminescent material SiO2 β–diketone |
topic |
Bioimaging Functionalization Lanthanide Luminescent material SiO2 β–diketone |
description |
Luminescent organic-inorganic hybrids containing lanthanides (Ln3+) have been prominent for applications such as luminescent bio-probes in biological assays. In this sense, a luminescent hybrid based on dense silica (SiO2) nanospheres decorated with Eu3+ β–diketonate complexes using dibenzoylmethane (Hdbm) as a luminescent antenna was developed by using a hierarchical organization in four steps: (i) anchoring of 3-aminopropyltriethoxysilane (APTES) organosilane on the SiO2 surface, (ii) formation of a carboxylic acid ligand, (iii) coordination of Eu3+ to the carboxylate groups and (iv) coordination of dbm− to Eu3+. The hybrid structure was elucidated through the correlation of thermogravimetry, silicon nuclear magnetic resonance and photoluminescence. Results indicate that the carboxylic acid-Eu3+-dbm hybrid was formed on the surface of the particles with no detectable changes on their size or shape after all the four steps (average size of 32 ± 7 nm). A surface charge of −27.8 mV was achieved for the hybrid, assuring a stable suspension in aqueous media. The Eu3+ complex provides intense red luminescence, characteristic of Eu3+ 5D0→7FJ electronic transitions, with an intrinsic emission quantum yield of 38%, even in an aqueous suspension. Therefore, the correlation of luminescence, structure, particle morphology and fluorescence microscopy images make the hybrid promising for application in bioimaging. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 2021-06-25T10:17:27Z 2021-06-25T10:17:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/ma13235494 Materials, v. 13, n. 23, p. 1-17, 2020. 1996-1944 http://hdl.handle.net/11449/205558 10.3390/ma13235494 2-s2.0-85097026347 |
url |
http://dx.doi.org/10.3390/ma13235494 http://hdl.handle.net/11449/205558 |
identifier_str_mv |
Materials, v. 13, n. 23, p. 1-17, 2020. 1996-1944 10.3390/ma13235494 2-s2.0-85097026347 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-17 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128760750276608 |