A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/S0040-8166(96)80059-0 http://hdl.handle.net/11449/219186 |
Resumo: | A quantitative evaluation of the types of afferent synaptic contacts in the pars oralis, using transganglionic degeneration and a comparison of previous data obtained from the pars interpolaris of the rat was performed. Following left inferior alveolar nerve transection or partial pulpectomy of the first and second left lower molar teeth well-defined degenerating terminals appeared bilaterally. In both experiments, the majority of these afferent synapses formed single asymmetric contacts with intermediate and distal dendritic segments in the pars oralis. Fewer contacts were observed with dendritic spines, proximal dendritic segments, perikarya, and other terminals. Double and multiple synaptic contacts, preferentially with small dendritic profiles, were also found. Pars oralis showed higher density of degenerating terminals and higher proportion of the contralateral contacts than pars interpolaris suggesting that it is a prime input area and that it may play a role in the bilateral management of sensory information. Pars oralis showed a higher density of contacts with intermediate and distal dendritic segment and a lower density of double contacts in comparison to the pars interpolaris. Partial pulpectomy revealed a distribution in synaptic types similar to that following IAN transection suggesting that sensory fibers conveying pain-related stimuli are not distinguished from fibers of other sensory modalities as to preference of synaptic contacts. The overall pattern demonstrates a structural organization of the sensory inputs to the spinal trigeminal nucleus regarding the bilateral handling of sensory information. |
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Repositório Institucional da UNESP |
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A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the ratInferior alveolar nerve afferentInterpolarisOralisSynapsesTooth pulp afferentTransganglionic degenerationTrigeminalA quantitative evaluation of the types of afferent synaptic contacts in the pars oralis, using transganglionic degeneration and a comparison of previous data obtained from the pars interpolaris of the rat was performed. Following left inferior alveolar nerve transection or partial pulpectomy of the first and second left lower molar teeth well-defined degenerating terminals appeared bilaterally. In both experiments, the majority of these afferent synapses formed single asymmetric contacts with intermediate and distal dendritic segments in the pars oralis. Fewer contacts were observed with dendritic spines, proximal dendritic segments, perikarya, and other terminals. Double and multiple synaptic contacts, preferentially with small dendritic profiles, were also found. Pars oralis showed higher density of degenerating terminals and higher proportion of the contralateral contacts than pars interpolaris suggesting that it is a prime input area and that it may play a role in the bilateral management of sensory information. Pars oralis showed a higher density of contacts with intermediate and distal dendritic segment and a lower density of double contacts in comparison to the pars interpolaris. Partial pulpectomy revealed a distribution in synaptic types similar to that following IAN transection suggesting that sensory fibers conveying pain-related stimuli are not distinguished from fibers of other sensory modalities as to preference of synaptic contacts. The overall pattern demonstrates a structural organization of the sensory inputs to the spinal trigeminal nucleus regarding the bilateral handling of sensory information.Department of Histology Escola Paulista de Medicina Universidade Federal de São Paulo, Rua Botucatu 740, 04023-062 São Paulo, SPDepartment of Histology Universidade Estadual de São Paulo, São PauloDepartment of Histology Universidade Estadual de São Paulo, São PauloUniversidade Federal de São Paulo (UNIFESP)Universidade Estadual Paulista (UNESP)Lapa, R. C.R.S.Bauer, J. A. [UNESP]Lindsey, C. J.2022-04-28T18:54:08Z2022-04-28T18:54:08Z1996-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article569-576http://dx.doi.org/10.1016/S0040-8166(96)80059-0Tissue and Cell, v. 28, n. 5, p. 569-576, 1996.0040-8166http://hdl.handle.net/11449/21918610.1016/S0040-8166(96)80059-02-s2.0-0029840966Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTissue and Cellinfo:eu-repo/semantics/openAccess2022-04-28T18:54:08Zoai:repositorio.unesp.br:11449/219186Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:00:43.384763Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
title |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
spellingShingle |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat Lapa, R. C.R.S. Inferior alveolar nerve afferent Interpolaris Oralis Synapses Tooth pulp afferent Transganglionic degeneration Trigeminal |
title_short |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
title_full |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
title_fullStr |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
title_full_unstemmed |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
title_sort |
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat |
author |
Lapa, R. C.R.S. |
author_facet |
Lapa, R. C.R.S. Bauer, J. A. [UNESP] Lindsey, C. J. |
author_role |
author |
author2 |
Bauer, J. A. [UNESP] Lindsey, C. J. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Lapa, R. C.R.S. Bauer, J. A. [UNESP] Lindsey, C. J. |
dc.subject.por.fl_str_mv |
Inferior alveolar nerve afferent Interpolaris Oralis Synapses Tooth pulp afferent Transganglionic degeneration Trigeminal |
topic |
Inferior alveolar nerve afferent Interpolaris Oralis Synapses Tooth pulp afferent Transganglionic degeneration Trigeminal |
description |
A quantitative evaluation of the types of afferent synaptic contacts in the pars oralis, using transganglionic degeneration and a comparison of previous data obtained from the pars interpolaris of the rat was performed. Following left inferior alveolar nerve transection or partial pulpectomy of the first and second left lower molar teeth well-defined degenerating terminals appeared bilaterally. In both experiments, the majority of these afferent synapses formed single asymmetric contacts with intermediate and distal dendritic segments in the pars oralis. Fewer contacts were observed with dendritic spines, proximal dendritic segments, perikarya, and other terminals. Double and multiple synaptic contacts, preferentially with small dendritic profiles, were also found. Pars oralis showed higher density of degenerating terminals and higher proportion of the contralateral contacts than pars interpolaris suggesting that it is a prime input area and that it may play a role in the bilateral management of sensory information. Pars oralis showed a higher density of contacts with intermediate and distal dendritic segment and a lower density of double contacts in comparison to the pars interpolaris. Partial pulpectomy revealed a distribution in synaptic types similar to that following IAN transection suggesting that sensory fibers conveying pain-related stimuli are not distinguished from fibers of other sensory modalities as to preference of synaptic contacts. The overall pattern demonstrates a structural organization of the sensory inputs to the spinal trigeminal nucleus regarding the bilateral handling of sensory information. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-01-01 2022-04-28T18:54:08Z 2022-04-28T18:54:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/S0040-8166(96)80059-0 Tissue and Cell, v. 28, n. 5, p. 569-576, 1996. 0040-8166 http://hdl.handle.net/11449/219186 10.1016/S0040-8166(96)80059-0 2-s2.0-0029840966 |
url |
http://dx.doi.org/10.1016/S0040-8166(96)80059-0 http://hdl.handle.net/11449/219186 |
identifier_str_mv |
Tissue and Cell, v. 28, n. 5, p. 569-576, 1996. 0040-8166 10.1016/S0040-8166(96)80059-0 2-s2.0-0029840966 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Tissue and Cell |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
569-576 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129148863905792 |