Tissue response to different incision tools in animal model

• Autor(a) principal: Torres-Augusto Neto, Renato [UNESP]
• Data de Publicação: 2022
• Outros Autores: Comachio, Cássio Amaro [UNESP], de Almeida, Lilian Caldas Quirino [UNESP], de Azambuja Carvalho, Pedro Henrique [UNESP], dos Santos Trento, Guilherme [UNESP], Pereira-Filho, Valfrido Antônio [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1007/s10006-022-01105-7; http://hdl.handle.net/11449/241453
• topic: Diode laser; Electrocoagulation; Microdissection; Surgical wound; Wound healing

Purpose: The aim of this study is to compare the repair of incisions performed with microdissection electrocautery tip, conventional electrocautery tip, high potency diode laser, and conventional scalpel blade in a in vivo model. Methods: Different incisions were performed in adults Holtzman rats using the four types of instruments: microdissection electrocautery tip, conventional electrocautery tip, high potency diode laser, and conventional scalpel blade, in different periods of healing process. Thirty rats were divided into 5 groups, according to the period of euthanasia—24 h, 48 h, 72 h, 7 days, and 14 days. All animals received four incisions, each by a different method. Quantitative histological and histomorphometric analyses were performed using hematoxylin and eosin (HE) and Picrosirius Red staining. Results: Inflammatory profile and tissue repair presented small statistically significance differences comparing conventional scalpel blade and microdissection tip; moreover, both presented quantitatively superior to the others. Conclusion: It is believed that the microdissection tip can perform a dynamic incision just as a common scalpel blade, but more effective. Furthermore, it can promote a better hemostatic control of the surgical field that is comparable to conventional electrocautery tip without affecting tissue repair.