Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity

Detalhes bibliográficos
Autor(a) principal: Tanomaru, Juliane Maria Guerreiro [UNESP]
Data de Publicação: 2013
Outros Autores: Pereira, Kamila de Figueiredo [UNESP], Nascimento, Camila Almeida [UNESP], Bernardi, Maria Inês Basso, Tanomaru Filho, Mario [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.scielo.org.ar/scielo.php?pid=S1852-48342013000300003&script=sci_arttext
http://hdl.handle.net/11449/126108
Resumo: The aim of this study was to evaluate the pH and antimicrobial activity of micro or nanoparticulate zinc oxide (ZnO) pastes with or without calcium hydroxide (CH). The following medications were evaluated: microparticulate ZnO + polyethylene glycol (PEG) 400; nanoparticulate ZnO + PEG 400; PEG 400; CH + microparticulate ZnO + PEG 400 and CH + nanoparticulate ZnO + PEG 400. The pH was assessed between 12 hours and 28 days, using a digital pH meter. The antimicrobial activity against Enterococcus faecalis (ATCC-9212), Candida albicans (ATCC-10231), Pseudomonas aeruginosa (ATCC-27853), Staphylococcus aureus (ATCC-6538) and Kocuria rhizophila (ATCC-9341) was determined in triplicate using agar diffusion test. The results were submitted to Kruskal-Wallis/Dunn and ANOVA/Tukey tests with 5% significance. The highest pH values were found for CH+ZnO, with higher values for nanoparticulate ZnO after 12 hours and 21 days (p<0.05). CH+ZnO medication promoted higher growth inhibition against P. aeruginosa and lower against E. faecalis. Calcium hydroxide pastes have higher pH and antimicrobial activity when associated with either micro- or nanoparticulate zinc oxide.
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spelling Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activityUso de óxido de zinco nanoparticulado como medicação em endodontia: ph e atividade antimicrobianaCalcium hydroxideNanoparticleZinc oxideintracanal medicationNanoparticlesCalcium HydroxideZinc OxideDesinfecçãoThe aim of this study was to evaluate the pH and antimicrobial activity of micro or nanoparticulate zinc oxide (ZnO) pastes with or without calcium hydroxide (CH). The following medications were evaluated: microparticulate ZnO + polyethylene glycol (PEG) 400; nanoparticulate ZnO + PEG 400; PEG 400; CH + microparticulate ZnO + PEG 400 and CH + nanoparticulate ZnO + PEG 400. The pH was assessed between 12 hours and 28 days, using a digital pH meter. The antimicrobial activity against Enterococcus faecalis (ATCC-9212), Candida albicans (ATCC-10231), Pseudomonas aeruginosa (ATCC-27853), Staphylococcus aureus (ATCC-6538) and Kocuria rhizophila (ATCC-9341) was determined in triplicate using agar diffusion test. The results were submitted to Kruskal-Wallis/Dunn and ANOVA/Tukey tests with 5% significance. The highest pH values were found for CH+ZnO, with higher values for nanoparticulate ZnO after 12 hours and 21 days (p<0.05). CH+ZnO medication promoted higher growth inhibition against P. aeruginosa and lower against E. faecalis. Calcium hydroxide pastes have higher pH and antimicrobial activity when associated with either micro- or nanoparticulate zinc oxide.O objetivo do estudo foi avaliar o pH e atividade antimicrobiana de pastas de oxido de zinco micro ou nanoparticulado (OZn) com ou sem hidroxido de calcio (HC). As medicacoes avaliadas foram OZn microparticulado + polietilenoglicol (PLG) 400; OZn nanoparticulado + PLG 400; PLG 400; HC + OZn microparticulado + PLG 400 e HC + OZn nanoparticulado + PLG 400. A analise do pH foi realizada entre 12 horas e 28 dias, usando um pHmetro digital. A atividade antimicrobiana frente Enterococcus faecalis (ATCC-9212), Candida albicans (ATCC-10231), Pseudomonas aeruginosa (ATCC-27853), Staphylococcus aureus (ATCC-6538) e Kocuria rhizophila (ATCC-9341) foi determinada, em triplicata, pelo teste de difusao em agar. Os resultados submetidos ao teste Kruskal-Wallis e Dunn e ANOVA e Tukey com 5% de significancia. Os maiores valores de pH ocorreram para HC+ZnO, sendo maior para ZnO nanoparticulado apos 12 horas e 21 dias (p<0,05). A medicacao de HC+ZnO promoveu maior inibicao de crescimento sobre P. aeruginosa e menor sobre E. faecalis. As pastas de hidroxido de calico apresentam os maiores valores de pH atividade antimicrobiana com a associacao de oxido de zinco micro ou nanoparticulado.Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680 - 3o Andar, Centro, CEP 14801-903, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá, 1680 - 3o Andar, Centro, CEP 14801-903, SP, BrasilUniversidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Tanomaru, Juliane Maria Guerreiro [UNESP]Pereira, Kamila de Figueiredo [UNESP]Nascimento, Camila Almeida [UNESP]Bernardi, Maria Inês BassoTanomaru Filho, Mario [UNESP]2015-08-06T16:13:58Z2015-08-06T16:13:58Z2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article144-148http://www.scielo.org.ar/scielo.php?pid=S1852-48342013000300003&script=sci_arttextActa Odontológica Latinoamericana, v. 26, n. 3, p. 144-148, 2013.0326-4815http://hdl.handle.net/11449/126108790655732417893826652112985847516221726991375516Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Odontológica Latinoamericana0,264info:eu-repo/semantics/openAccess2024-09-27T18:04:08Zoai:repositorio.unesp.br:11449/126108Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-27T18:04:08Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
Uso de óxido de zinco nanoparticulado como medicação em endodontia: ph e atividade antimicrobiana
title Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
spellingShingle Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
Tanomaru, Juliane Maria Guerreiro [UNESP]
Calcium hydroxide
Nanoparticle
Zinc oxide
intracanal medication
Nanoparticles
Calcium Hydroxide
Zinc Oxide
Desinfecção
title_short Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
title_full Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
title_fullStr Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
title_full_unstemmed Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
title_sort Use of nanoparticulate zinc oxide as intracanal medication in endodontics: pH and antimicrobial activity
author Tanomaru, Juliane Maria Guerreiro [UNESP]
author_facet Tanomaru, Juliane Maria Guerreiro [UNESP]
Pereira, Kamila de Figueiredo [UNESP]
Nascimento, Camila Almeida [UNESP]
Bernardi, Maria Inês Basso
Tanomaru Filho, Mario [UNESP]
author_role author
author2 Pereira, Kamila de Figueiredo [UNESP]
Nascimento, Camila Almeida [UNESP]
Bernardi, Maria Inês Basso
Tanomaru Filho, Mario [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Tanomaru, Juliane Maria Guerreiro [UNESP]
Pereira, Kamila de Figueiredo [UNESP]
Nascimento, Camila Almeida [UNESP]
Bernardi, Maria Inês Basso
Tanomaru Filho, Mario [UNESP]
dc.subject.por.fl_str_mv Calcium hydroxide
Nanoparticle
Zinc oxide
intracanal medication
Nanoparticles
Calcium Hydroxide
Zinc Oxide
Desinfecção
topic Calcium hydroxide
Nanoparticle
Zinc oxide
intracanal medication
Nanoparticles
Calcium Hydroxide
Zinc Oxide
Desinfecção
description The aim of this study was to evaluate the pH and antimicrobial activity of micro or nanoparticulate zinc oxide (ZnO) pastes with or without calcium hydroxide (CH). The following medications were evaluated: microparticulate ZnO + polyethylene glycol (PEG) 400; nanoparticulate ZnO + PEG 400; PEG 400; CH + microparticulate ZnO + PEG 400 and CH + nanoparticulate ZnO + PEG 400. The pH was assessed between 12 hours and 28 days, using a digital pH meter. The antimicrobial activity against Enterococcus faecalis (ATCC-9212), Candida albicans (ATCC-10231), Pseudomonas aeruginosa (ATCC-27853), Staphylococcus aureus (ATCC-6538) and Kocuria rhizophila (ATCC-9341) was determined in triplicate using agar diffusion test. The results were submitted to Kruskal-Wallis/Dunn and ANOVA/Tukey tests with 5% significance. The highest pH values were found for CH+ZnO, with higher values for nanoparticulate ZnO after 12 hours and 21 days (p<0.05). CH+ZnO medication promoted higher growth inhibition against P. aeruginosa and lower against E. faecalis. Calcium hydroxide pastes have higher pH and antimicrobial activity when associated with either micro- or nanoparticulate zinc oxide.
publishDate 2013
dc.date.none.fl_str_mv 2013
2015-08-06T16:13:58Z
2015-08-06T16:13:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.org.ar/scielo.php?pid=S1852-48342013000300003&script=sci_arttext
Acta Odontológica Latinoamericana, v. 26, n. 3, p. 144-148, 2013.
0326-4815
http://hdl.handle.net/11449/126108
7906557324178938
2665211298584751
6221726991375516
url http://www.scielo.org.ar/scielo.php?pid=S1852-48342013000300003&script=sci_arttext
http://hdl.handle.net/11449/126108
identifier_str_mv Acta Odontológica Latinoamericana, v. 26, n. 3, p. 144-148, 2013.
0326-4815
7906557324178938
2665211298584751
6221726991375516
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Odontológica Latinoamericana
0,264
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 144-148
dc.source.none.fl_str_mv Currículo Lattes
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1813546459195244544

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