Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: deCastro, Alessandra M. M. G.
Data de Publicação: 2012
Outros Autores: Cruz, Tais F. [UNESP], Salgado, Vanessa R., Kanashiro, Tatiana M. [UNESP], Ferrari, Karen L., Araujo, Joao P. [UNESP], Brandao, Paulo E., Richtzenhain, Leonardo J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/1751-0147-54-29
http://hdl.handle.net/11449/18276
Resumo: Background: Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious organisms.Findings: Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction (PCR). Positive samples were additionally tested for porcine parvovirus (PPV), Leptospira spp. and Brucella spp. by PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, Brucella spp. and Leptospira spp were found in 2, 10 and 0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b (n = 10).Conclusions: The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid protein seemed to be associated with abortion in sows.
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spelling Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, BrazilPigAbortionPorcine circovirusPorcine parvovirusBrucellaBackground: Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious organisms.Findings: Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction (PCR). Positive samples were additionally tested for porcine parvovirus (PPV), Leptospira spp. and Brucella spp. by PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, Brucella spp. and Leptospira spp were found in 2, 10 and 0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b (n = 10).Conclusions: The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid protein seemed to be associated with abortion in sows.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ São Paulo, Dept Prevent Vet Med & Anim Hlth, Coll Vet Med, BR-05508270 São Paulo, BrazilSão Paulo State Univ, Dept Immunol & Microbiol, Inst Biosci, Coll Vet Med, BR-186180 Botucatu, SP, BrazilSão Paulo State Univ, Dept Immunol & Microbiol, Inst Biosci, Coll Vet Med, BR-186180 Botucatu, SP, BrazilFAPESP: 07/50003-5Biomed Central Ltd.Universidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)deCastro, Alessandra M. M. G.Cruz, Tais F. [UNESP]Salgado, Vanessa R.Kanashiro, Tatiana M. [UNESP]Ferrari, Karen L.Araujo, Joao P. [UNESP]Brandao, Paulo E.Richtzenhain, Leonardo J.2014-05-20T13:51:11Z2014-05-20T13:51:11Z2012-05-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4application/pdfhttp://dx.doi.org/10.1186/1751-0147-54-29Acta Veterinaria Scandinavica. London: Biomed Central Ltd., v. 54, p. 4, 2012.0044-605Xhttp://hdl.handle.net/11449/1827610.1186/1751-0147-54-29WOS:000308347400001WOS000308347400001.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Veterinaria Scandinavica1.497info:eu-repo/semantics/openAccess2023-11-27T06:14:13Zoai:repositorio.unesp.br:11449/18276Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-27T06:14:13Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
title Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
spellingShingle Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
deCastro, Alessandra M. M. G.
Pig
Abortion
Porcine circovirus
Porcine parvovirus
Brucella
title_short Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
title_full Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
title_fullStr Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
title_full_unstemmed Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
title_sort Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
author deCastro, Alessandra M. M. G.
author_facet deCastro, Alessandra M. M. G.
Cruz, Tais F. [UNESP]
Salgado, Vanessa R.
Kanashiro, Tatiana M. [UNESP]
Ferrari, Karen L.
Araujo, Joao P. [UNESP]
Brandao, Paulo E.
Richtzenhain, Leonardo J.
author_role author
author2 Cruz, Tais F. [UNESP]
Salgado, Vanessa R.
Kanashiro, Tatiana M. [UNESP]
Ferrari, Karen L.
Araujo, Joao P. [UNESP]
Brandao, Paulo E.
Richtzenhain, Leonardo J.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv deCastro, Alessandra M. M. G.
Cruz, Tais F. [UNESP]
Salgado, Vanessa R.
Kanashiro, Tatiana M. [UNESP]
Ferrari, Karen L.
Araujo, Joao P. [UNESP]
Brandao, Paulo E.
Richtzenhain, Leonardo J.
dc.subject.por.fl_str_mv Pig
Abortion
Porcine circovirus
Porcine parvovirus
Brucella
topic Pig
Abortion
Porcine circovirus
Porcine parvovirus
Brucella
description Background: Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious organisms.Findings: Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction (PCR). Positive samples were additionally tested for porcine parvovirus (PPV), Leptospira spp. and Brucella spp. by PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, Brucella spp. and Leptospira spp were found in 2, 10 and 0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b (n = 10).Conclusions: The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid protein seemed to be associated with abortion in sows.
publishDate 2012
dc.date.none.fl_str_mv 2012-05-03
2014-05-20T13:51:11Z
2014-05-20T13:51:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/1751-0147-54-29
Acta Veterinaria Scandinavica. London: Biomed Central Ltd., v. 54, p. 4, 2012.
0044-605X
http://hdl.handle.net/11449/18276
10.1186/1751-0147-54-29
WOS:000308347400001
WOS000308347400001.pdf
url http://dx.doi.org/10.1186/1751-0147-54-29
http://hdl.handle.net/11449/18276
identifier_str_mv Acta Veterinaria Scandinavica. London: Biomed Central Ltd., v. 54, p. 4, 2012.
0044-605X
10.1186/1751-0147-54-29
WOS:000308347400001
WOS000308347400001.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Veterinaria Scandinavica
1.497
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eu_rights_str_mv openAccess
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application/pdf
dc.publisher.none.fl_str_mv Biomed Central Ltd.
publisher.none.fl_str_mv Biomed Central Ltd.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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