Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.2527/1996.7451074x http://hdl.handle.net/11449/219192 |
Resumo: | A series of experiments with Holstein heifers was conducted to develop the capability of inducing accessory corpus luteum (CL) with a GnRH agonist (Buserelin, 8 μg; GnRHa) or hCG (3,000 IU) to increase plasma progesterone concentrations (Exp. 1, 2, and 3) and to test whether induction of accessory CL with hCG will increase conception rates in heifers (Exp. 4) and lactating cows (Exp. 5). In Exp. 1, heifers were treated on d 5 after estrus with GnRHa (n = 8) or saline (n = 7); heifers in Exp. 2 received hCG (n = 5) or saline (n = 4) on d 5. Experiment 3 allowed a contemporary evaluation of heifers treated on d 5 with GnRHa (n = 6), hCG (n = 6), saline (n = 6), or GnRHa at d 5 and hCG at the time of the induced ovulation (n = 5). The GnRHa and hCG were equally effective in inducing an accessory CL (93% induction rate), but the subsequent increase in progesterone concentrations was greater in hCG-treated heifers. A greater half life of hCG may provide longer LH-like stimulation of the first-wave follicle and subsequent developing accessory CL or a greater luteotropic effect on the original CL. Induction of an accessory CL with hCG on d 5 or 6 after insemination did not increase pregnancy rates in fertile heifers (Exp. 4: hCG = 64.8% vs control = 62.9%; n = 243) or lactating dairy cows during summer heat stress (Exp. 5: hCG = 24.2% vs control = 23.5%; n = 201). |
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Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing HormoneCorpus LuteumFertilityFolliclesGnRH AgonisthCGProgesteroneA series of experiments with Holstein heifers was conducted to develop the capability of inducing accessory corpus luteum (CL) with a GnRH agonist (Buserelin, 8 μg; GnRHa) or hCG (3,000 IU) to increase plasma progesterone concentrations (Exp. 1, 2, and 3) and to test whether induction of accessory CL with hCG will increase conception rates in heifers (Exp. 4) and lactating cows (Exp. 5). In Exp. 1, heifers were treated on d 5 after estrus with GnRHa (n = 8) or saline (n = 7); heifers in Exp. 2 received hCG (n = 5) or saline (n = 4) on d 5. Experiment 3 allowed a contemporary evaluation of heifers treated on d 5 with GnRHa (n = 6), hCG (n = 6), saline (n = 6), or GnRHa at d 5 and hCG at the time of the induced ovulation (n = 5). The GnRHa and hCG were equally effective in inducing an accessory CL (93% induction rate), but the subsequent increase in progesterone concentrations was greater in hCG-treated heifers. A greater half life of hCG may provide longer LH-like stimulation of the first-wave follicle and subsequent developing accessory CL or a greater luteotropic effect on the original CL. Induction of an accessory CL with hCG on d 5 or 6 after insemination did not increase pregnancy rates in fertile heifers (Exp. 4: hCG = 64.8% vs control = 62.9%; n = 243) or lactating dairy cows during summer heat stress (Exp. 5: hCG = 24.2% vs control = 23.5%; n = 201).Dept. of Dairy and Poultry Sciences University of Florida, Gainesville, FL 32611Dept. of Large Anim. Clin. Sciences University of Florida, Gainesville, FL 32611Department of Pharmacology UNESP, São Paulo 18600South Florida Center for Fertility, Miami, FL 33143Department of Pharmacology UNESP, São Paulo 18600University of FloridaUniversidade Estadual Paulista (UNESP)South Florida Center for FertilitySchmitt, É J.P.Diaz, T.Barros, C. M. [UNESP]De La Sota, R. L.Drost, M.Fredriksson, E. W.Staples, C. R.Thorner, R.Thatcher, W. W.2022-04-28T18:54:10Z2022-04-28T18:54:10Z1996-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1074-1083http://dx.doi.org/10.2527/1996.7451074xJournal of Animal Science, v. 74, n. 5, p. 1074-1083, 1996.0021-8812http://hdl.handle.net/11449/21919210.2527/1996.7451074x2-s2.0-0030144856Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Animal Scienceinfo:eu-repo/semantics/openAccess2022-04-28T18:54:10Zoai:repositorio.unesp.br:11449/219192Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:37:11.613149Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
title |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
spellingShingle |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone Schmitt, É J.P. Corpus Luteum Fertility Follicles GnRH Agonist hCG Progesterone |
title_short |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
title_full |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
title_fullStr |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
title_full_unstemmed |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
title_sort |
Differential Response of the Luteal Phase and Fertility in Cattle Following Ovulation of the First-Wave Follicle with Human Chorionic Gonadotropin or an Agonist of Gonadotropin-Releasing Hormone |
author |
Schmitt, É J.P. |
author_facet |
Schmitt, É J.P. Diaz, T. Barros, C. M. [UNESP] De La Sota, R. L. Drost, M. Fredriksson, E. W. Staples, C. R. Thorner, R. Thatcher, W. W. |
author_role |
author |
author2 |
Diaz, T. Barros, C. M. [UNESP] De La Sota, R. L. Drost, M. Fredriksson, E. W. Staples, C. R. Thorner, R. Thatcher, W. W. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
University of Florida Universidade Estadual Paulista (UNESP) South Florida Center for Fertility |
dc.contributor.author.fl_str_mv |
Schmitt, É J.P. Diaz, T. Barros, C. M. [UNESP] De La Sota, R. L. Drost, M. Fredriksson, E. W. Staples, C. R. Thorner, R. Thatcher, W. W. |
dc.subject.por.fl_str_mv |
Corpus Luteum Fertility Follicles GnRH Agonist hCG Progesterone |
topic |
Corpus Luteum Fertility Follicles GnRH Agonist hCG Progesterone |
description |
A series of experiments with Holstein heifers was conducted to develop the capability of inducing accessory corpus luteum (CL) with a GnRH agonist (Buserelin, 8 μg; GnRHa) or hCG (3,000 IU) to increase plasma progesterone concentrations (Exp. 1, 2, and 3) and to test whether induction of accessory CL with hCG will increase conception rates in heifers (Exp. 4) and lactating cows (Exp. 5). In Exp. 1, heifers were treated on d 5 after estrus with GnRHa (n = 8) or saline (n = 7); heifers in Exp. 2 received hCG (n = 5) or saline (n = 4) on d 5. Experiment 3 allowed a contemporary evaluation of heifers treated on d 5 with GnRHa (n = 6), hCG (n = 6), saline (n = 6), or GnRHa at d 5 and hCG at the time of the induced ovulation (n = 5). The GnRHa and hCG were equally effective in inducing an accessory CL (93% induction rate), but the subsequent increase in progesterone concentrations was greater in hCG-treated heifers. A greater half life of hCG may provide longer LH-like stimulation of the first-wave follicle and subsequent developing accessory CL or a greater luteotropic effect on the original CL. Induction of an accessory CL with hCG on d 5 or 6 after insemination did not increase pregnancy rates in fertile heifers (Exp. 4: hCG = 64.8% vs control = 62.9%; n = 243) or lactating dairy cows during summer heat stress (Exp. 5: hCG = 24.2% vs control = 23.5%; n = 201). |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-01-01 2022-04-28T18:54:10Z 2022-04-28T18:54:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.2527/1996.7451074x Journal of Animal Science, v. 74, n. 5, p. 1074-1083, 1996. 0021-8812 http://hdl.handle.net/11449/219192 10.2527/1996.7451074x 2-s2.0-0030144856 |
url |
http://dx.doi.org/10.2527/1996.7451074x http://hdl.handle.net/11449/219192 |
identifier_str_mv |
Journal of Animal Science, v. 74, n. 5, p. 1074-1083, 1996. 0021-8812 10.2527/1996.7451074x 2-s2.0-0030144856 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Animal Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1074-1083 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128388986044416 |