The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol

Detalhes bibliográficos
Autor(a) principal: Beguelini, Mateus R.
Data de Publicação: 2021
Outros Autores: Santiago, Cornélio S., Guerra, Luiz H. A. [UNESP], Santos, Fernanda C. A., Góes, Rejane M. [UNESP], Morielle-Versute, Eliana [UNESP], Taboga, Sebastião R. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/s00441-020-03342-2
http://hdl.handle.net/11449/207120
Resumo: Myotis nigricans is a species of bat from the Vespertilionidae family that is endemic of the Neotropical region. Its insectivorous feeding habit plus its large range of prey species, great geographical dispersion, wide colonies, and anthropomorphized behavior make this species an important ecological agent that acts in the control of nocturnal insects. Reproductively, M. nigricans presents geographic variations, having different patterns of reproduction according to its geographical location. Despite these extremely interesting characteristics, no more detailed study of the hormonal control of the reproduction of this species has been conducted. Therefore, the aim of the present study was to evaluate the variations in serum hormone concentrations and in uterine hormonal control of this bat during its different reproductive phases. Twenty adult females were collected, divided into four (4) sample groups, according to the reproductive status (nonreproductive, initial, and advanced pregnancy and lactating), and submitted to hormone dosage and immunohistochemical analyses. The results demonstrated that the uterus of M. nigricans is strongly regulated by the interaction/cross-talk between serum concentrations of estradiol (E2) and progesterone with their respective hormone receptors. Significant increases in the concentration of E2 and progesterone are needed to regulate the early pregnancy. The persistence of the corpus luteum throughout pregnancy is necessary, since its placenta does not express aromatase. The expressions of ERα and PR appear to be synchronized in order to coordinate a large portion of the processes that occur inside the uterus of M. nigricans during pregnancy and lactation.
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spelling The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiolAromataseEstradiolProgesteroneUterusMyotis nigricans is a species of bat from the Vespertilionidae family that is endemic of the Neotropical region. Its insectivorous feeding habit plus its large range of prey species, great geographical dispersion, wide colonies, and anthropomorphized behavior make this species an important ecological agent that acts in the control of nocturnal insects. Reproductively, M. nigricans presents geographic variations, having different patterns of reproduction according to its geographical location. Despite these extremely interesting characteristics, no more detailed study of the hormonal control of the reproduction of this species has been conducted. Therefore, the aim of the present study was to evaluate the variations in serum hormone concentrations and in uterine hormonal control of this bat during its different reproductive phases. Twenty adult females were collected, divided into four (4) sample groups, according to the reproductive status (nonreproductive, initial, and advanced pregnancy and lactating), and submitted to hormone dosage and immunohistochemical analyses. The results demonstrated that the uterus of M. nigricans is strongly regulated by the interaction/cross-talk between serum concentrations of estradiol (E2) and progesterone with their respective hormone receptors. Significant increases in the concentration of E2 and progesterone are needed to regulate the early pregnancy. The persistence of the corpus luteum throughout pregnancy is necessary, since its placenta does not express aromatase. The expressions of ERα and PR appear to be synchronized in order to coordinate a large portion of the processes that occur inside the uterus of M. nigricans during pregnancy and lactation.Center of Biological and Health Science UFOB - Universidade Federal Do Oeste da BahiaDepartment of Biology UNESP – University Estadual Paulista São José Do Rio PretoDepartment of Histology and Embryology UFG – Universidade Federal de GoiásDepartment of Zoology and Botany UNESP – University Estadual Paulista São José Do Rio PretoDepartment of Biology UNESP – University Estadual Paulista São José Do Rio PretoDepartment of Zoology and Botany UNESP – University Estadual Paulista São José Do Rio PretoUFOB - Universidade Federal Do Oeste da BahiaUniversidade Estadual Paulista (Unesp)Universidade Federal de Goiás (UFG)Beguelini, Mateus R.Santiago, Cornélio S.Guerra, Luiz H. A. [UNESP]Santos, Fernanda C. A.Góes, Rejane M. [UNESP]Morielle-Versute, Eliana [UNESP]Taboga, Sebastião R. [UNESP]2021-06-25T10:49:18Z2021-06-25T10:49:18Z2021-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article211-229http://dx.doi.org/10.1007/s00441-020-03342-2Cell and Tissue Research, v. 384, n. 1, p. 211-229, 2021.1432-08780302-766Xhttp://hdl.handle.net/11449/20712010.1007/s00441-020-03342-22-s2.0-85099237325Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCell and Tissue Researchinfo:eu-repo/semantics/openAccess2021-10-23T15:48:33Zoai:repositorio.unesp.br:11449/207120Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:19:27.555437Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
title The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
spellingShingle The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
Beguelini, Mateus R.
Aromatase
Estradiol
Progesterone
Uterus
title_short The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
title_full The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
title_fullStr The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
title_full_unstemmed The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
title_sort The hormonal control of the uterus of the bat Myotis nigricans during its different reproductive phases: emphasis on progesterone and estradiol
author Beguelini, Mateus R.
author_facet Beguelini, Mateus R.
Santiago, Cornélio S.
Guerra, Luiz H. A. [UNESP]
Santos, Fernanda C. A.
Góes, Rejane M. [UNESP]
Morielle-Versute, Eliana [UNESP]
Taboga, Sebastião R. [UNESP]
author_role author
author2 Santiago, Cornélio S.
Guerra, Luiz H. A. [UNESP]
Santos, Fernanda C. A.
Góes, Rejane M. [UNESP]
Morielle-Versute, Eliana [UNESP]
Taboga, Sebastião R. [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv UFOB - Universidade Federal Do Oeste da Bahia
Universidade Estadual Paulista (Unesp)
Universidade Federal de Goiás (UFG)
dc.contributor.author.fl_str_mv Beguelini, Mateus R.
Santiago, Cornélio S.
Guerra, Luiz H. A. [UNESP]
Santos, Fernanda C. A.
Góes, Rejane M. [UNESP]
Morielle-Versute, Eliana [UNESP]
Taboga, Sebastião R. [UNESP]
dc.subject.por.fl_str_mv Aromatase
Estradiol
Progesterone
Uterus
topic Aromatase
Estradiol
Progesterone
Uterus
description Myotis nigricans is a species of bat from the Vespertilionidae family that is endemic of the Neotropical region. Its insectivorous feeding habit plus its large range of prey species, great geographical dispersion, wide colonies, and anthropomorphized behavior make this species an important ecological agent that acts in the control of nocturnal insects. Reproductively, M. nigricans presents geographic variations, having different patterns of reproduction according to its geographical location. Despite these extremely interesting characteristics, no more detailed study of the hormonal control of the reproduction of this species has been conducted. Therefore, the aim of the present study was to evaluate the variations in serum hormone concentrations and in uterine hormonal control of this bat during its different reproductive phases. Twenty adult females were collected, divided into four (4) sample groups, according to the reproductive status (nonreproductive, initial, and advanced pregnancy and lactating), and submitted to hormone dosage and immunohistochemical analyses. The results demonstrated that the uterus of M. nigricans is strongly regulated by the interaction/cross-talk between serum concentrations of estradiol (E2) and progesterone with their respective hormone receptors. Significant increases in the concentration of E2 and progesterone are needed to regulate the early pregnancy. The persistence of the corpus luteum throughout pregnancy is necessary, since its placenta does not express aromatase. The expressions of ERα and PR appear to be synchronized in order to coordinate a large portion of the processes that occur inside the uterus of M. nigricans during pregnancy and lactation.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T10:49:18Z
2021-06-25T10:49:18Z
2021-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s00441-020-03342-2
Cell and Tissue Research, v. 384, n. 1, p. 211-229, 2021.
1432-0878
0302-766X
http://hdl.handle.net/11449/207120
10.1007/s00441-020-03342-2
2-s2.0-85099237325
url http://dx.doi.org/10.1007/s00441-020-03342-2
http://hdl.handle.net/11449/207120
identifier_str_mv Cell and Tissue Research, v. 384, n. 1, p. 211-229, 2021.
1432-0878
0302-766X
10.1007/s00441-020-03342-2
2-s2.0-85099237325
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cell and Tissue Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 211-229
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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