Dental development of children and adolescents with cleft lip and palate
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en http://hdl.handle.net/11449/127326 |
Resumo: | Aim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning. |
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Dental development of children and adolescents with cleft lip and palateCleft lipCleft palateDentition, permanentAim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning.Display Diferencial (DD) é uma técnica amplamente utilizada em estudos de expressão diferencial. A maioria desses estudos envolvendo espécies de peixes está restrita a espécies da América do Norte e Europa ou a espécies comerciais, como os salmoniformes. Estudos relacionados a peixes da América do Sul são ainda pouco explorados. Desse modo, o presente trabalho teve como objetivo descrever modificações na técnica de DD, a fim de melhorar os resultados relacionados ao isolamento de DETs (Transcritos Diferencialmente Expressos), utilizando Leporinus macrocephalus, peixe explorado comercialmente na América do Sul, como espécie para tal delineamento. Diferentes abordagens de DDRT-PCR foram desenvolvidas a partir de amostras de tecido cerebral e os produtos das reações foram analisados em gel de poliacrilamida 6% corados com 0,17% de nitrato de Prata (AgNO3). A utilização de reações de PCR sob condições de elevada estringência e oligonucleotídeos mais longos, com base em sequências cerne de VNTR (Número Variável de Repetições em Tandem), mostrou melhores resultados quando comparada a condições de baixa estringência e ao uso de oligonucleotídeos decâmeros. A estratégia empregada permitiu o isolamento de transcritos diferencialmente expressos em machos e fêmeas adultos de L. macrocephalus. Este estudo evidencia que modificações no método de DDRT-PCR garantem o melhor isolamento de DETs a partir de diferentes tecidos de peixes e asseguram a obtenção de dados mais sólidos relacionados a essa abordagem.Universidade Estadual Paulista Araçatuba Dental School Department of Pediatric and Community DentistryUniversidade Federal do Paraná School of Dentistry Department of StomatologyKatholieke Universiteit LeuvenUniversidade Estadual Paulista Araçatuba Dental School Department of Pediatric and Community DentistryFaculdade de Odontologia de Piracicaba - UNICAMPUniversidade Estadual Paulista (Unesp)Universidade Federal do Paraná School of Dentistry Department of StomatologyKatholieke Universiteit LeuvenTopolski, Francielle [UNESP]Souza, Rafael Boscheti deFranco, AdemirCuoghi, Osmar Aparecido [UNESP]Assunção, Luciana Reichert Da SilvaFernandes, Ângela2015-08-26T19:19:12Z2015-08-26T19:19:12Z2014-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article319-324application/pdfhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=enBrazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014.1677-3225http://hdl.handle.net/11449/12732610.1590/1677-3225v13n4a15S1677-32252014000400319S1677-32252014000400319.pdf8568814008546317SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Oral Sciences0,131info:eu-repo/semantics/openAccess2024-09-19T17:55:53Zoai:repositorio.unesp.br:11449/127326Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T17:55:53Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Dental development of children and adolescents with cleft lip and palate |
title |
Dental development of children and adolescents with cleft lip and palate |
spellingShingle |
Dental development of children and adolescents with cleft lip and palate Topolski, Francielle [UNESP] Cleft lip Cleft palate Dentition, permanent |
title_short |
Dental development of children and adolescents with cleft lip and palate |
title_full |
Dental development of children and adolescents with cleft lip and palate |
title_fullStr |
Dental development of children and adolescents with cleft lip and palate |
title_full_unstemmed |
Dental development of children and adolescents with cleft lip and palate |
title_sort |
Dental development of children and adolescents with cleft lip and palate |
author |
Topolski, Francielle [UNESP] |
author_facet |
Topolski, Francielle [UNESP] Souza, Rafael Boscheti de Franco, Ademir Cuoghi, Osmar Aparecido [UNESP] Assunção, Luciana Reichert Da Silva Fernandes, Ângela |
author_role |
author |
author2 |
Souza, Rafael Boscheti de Franco, Ademir Cuoghi, Osmar Aparecido [UNESP] Assunção, Luciana Reichert Da Silva Fernandes, Ângela |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Paraná School of Dentistry Department of Stomatology Katholieke Universiteit Leuven |
dc.contributor.author.fl_str_mv |
Topolski, Francielle [UNESP] Souza, Rafael Boscheti de Franco, Ademir Cuoghi, Osmar Aparecido [UNESP] Assunção, Luciana Reichert Da Silva Fernandes, Ângela |
dc.subject.por.fl_str_mv |
Cleft lip Cleft palate Dentition, permanent |
topic |
Cleft lip Cleft palate Dentition, permanent |
description |
Aim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-01 2015-08-26T19:19:12Z 2015-08-26T19:19:12Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en Brazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014. 1677-3225 http://hdl.handle.net/11449/127326 10.1590/1677-3225v13n4a15 S1677-32252014000400319 S1677-32252014000400319.pdf 8568814008546317 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en http://hdl.handle.net/11449/127326 |
identifier_str_mv |
Brazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014. 1677-3225 10.1590/1677-3225v13n4a15 S1677-32252014000400319 S1677-32252014000400319.pdf 8568814008546317 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Oral Sciences 0,131 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
319-324 application/pdf |
dc.publisher.none.fl_str_mv |
Faculdade de Odontologia de Piracicaba - UNICAMP |
publisher.none.fl_str_mv |
Faculdade de Odontologia de Piracicaba - UNICAMP |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1813546387562823680 |