Dental development of children and adolescents with cleft lip and palate

Detalhes bibliográficos
Autor(a) principal: Topolski, Francielle [UNESP]
Data de Publicação: 2014
Outros Autores: Souza, Rafael Boscheti de, Franco, Ademir, Cuoghi, Osmar Aparecido [UNESP], Assunção, Luciana Reichert Da Silva, Fernandes, Ângela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en
http://hdl.handle.net/11449/127326
Resumo: Aim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning.
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spelling Dental development of children and adolescents with cleft lip and palateCleft lipCleft palateDentition, permanentAim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning.Display Diferencial (DD) é uma técnica amplamente utilizada em estudos de expressão diferencial. A maioria desses estudos envolvendo espécies de peixes está restrita a espécies da América do Norte e Europa ou a espécies comerciais, como os salmoniformes. Estudos relacionados a peixes da América do Sul são ainda pouco explorados. Desse modo, o presente trabalho teve como objetivo descrever modificações na técnica de DD, a fim de melhorar os resultados relacionados ao isolamento de DETs (Transcritos Diferencialmente Expressos), utilizando Leporinus macrocephalus, peixe explorado comercialmente na América do Sul, como espécie para tal delineamento. Diferentes abordagens de DDRT-PCR foram desenvolvidas a partir de amostras de tecido cerebral e os produtos das reações foram analisados em gel de poliacrilamida 6% corados com 0,17% de nitrato de Prata (AgNO3). A utilização de reações de PCR sob condições de elevada estringência e oligonucleotídeos mais longos, com base em sequências cerne de VNTR (Número Variável de Repetições em Tandem), mostrou melhores resultados quando comparada a condições de baixa estringência e ao uso de oligonucleotídeos decâmeros. A estratégia empregada permitiu o isolamento de transcritos diferencialmente expressos em machos e fêmeas adultos de L. macrocephalus. Este estudo evidencia que modificações no método de DDRT-PCR garantem o melhor isolamento de DETs a partir de diferentes tecidos de peixes e asseguram a obtenção de dados mais sólidos relacionados a essa abordagem.Universidade Estadual Paulista Araçatuba Dental School Department of Pediatric and Community DentistryUniversidade Federal do Paraná School of Dentistry Department of StomatologyKatholieke Universiteit LeuvenUniversidade Estadual Paulista Araçatuba Dental School Department of Pediatric and Community DentistryFaculdade de Odontologia de Piracicaba - UNICAMPUniversidade Estadual Paulista (Unesp)Universidade Federal do Paraná School of Dentistry Department of StomatologyKatholieke Universiteit LeuvenTopolski, Francielle [UNESP]Souza, Rafael Boscheti deFranco, AdemirCuoghi, Osmar Aparecido [UNESP]Assunção, Luciana Reichert Da SilvaFernandes, Ângela2015-08-26T19:19:12Z2015-08-26T19:19:12Z2014-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article319-324application/pdfhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=enBrazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014.1677-3225http://hdl.handle.net/11449/12732610.1590/1677-3225v13n4a15S1677-32252014000400319S1677-32252014000400319.pdf8568814008546317SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Oral Sciences0,131info:eu-repo/semantics/openAccess2024-09-19T17:55:53Zoai:repositorio.unesp.br:11449/127326Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T17:55:53Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Dental development of children and adolescents with cleft lip and palate
title Dental development of children and adolescents with cleft lip and palate
spellingShingle Dental development of children and adolescents with cleft lip and palate
Topolski, Francielle [UNESP]
Cleft lip
Cleft palate
Dentition, permanent
title_short Dental development of children and adolescents with cleft lip and palate
title_full Dental development of children and adolescents with cleft lip and palate
title_fullStr Dental development of children and adolescents with cleft lip and palate
title_full_unstemmed Dental development of children and adolescents with cleft lip and palate
title_sort Dental development of children and adolescents with cleft lip and palate
author Topolski, Francielle [UNESP]
author_facet Topolski, Francielle [UNESP]
Souza, Rafael Boscheti de
Franco, Ademir
Cuoghi, Osmar Aparecido [UNESP]
Assunção, Luciana Reichert Da Silva
Fernandes, Ângela
author_role author
author2 Souza, Rafael Boscheti de
Franco, Ademir
Cuoghi, Osmar Aparecido [UNESP]
Assunção, Luciana Reichert Da Silva
Fernandes, Ângela
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal do Paraná School of Dentistry Department of Stomatology
Katholieke Universiteit Leuven
dc.contributor.author.fl_str_mv Topolski, Francielle [UNESP]
Souza, Rafael Boscheti de
Franco, Ademir
Cuoghi, Osmar Aparecido [UNESP]
Assunção, Luciana Reichert Da Silva
Fernandes, Ângela
dc.subject.por.fl_str_mv Cleft lip
Cleft palate
Dentition, permanent
topic Cleft lip
Cleft palate
Dentition, permanent
description Aim: To evaluate the dental development of Brazilian children and adolescents with cleft lip and palate. Methods: The sample consisted of 107 panoramic radiographs of children and adolescents with cleft lip and/or palate (cleft group) and 107 panoramic radiographs of children and adolescents without cleft lip and/or palate (control group), with chronological ages ranging from 6 to 15 years, matched in gender and chronological age within 60 days. Radiographs were digitized and masked and dental age was assessed using the method described by Demirjian et al. (1973). Three trained examiners conducted the assessments. Each examiner evaluated the radiographs three times. Data were statistically analyzed using non-parametric tests and univariate linear regression (p<0.05). Results: The dental age was overestimated in relation to the chronological age in both groups (p<0.0001). Compared to the control group, there was a delay in the dental age in the cleft group of 0.17 years (2.1 months). However, no statistically significant difference in the dental age between the cleft and the control group was found even when considering the different cleft types (p=0.152). Conclusions: There was no statistically significant difference in the dental age between the cleft and the control groups. The evaluation of dental development in individuals with cleft lip and palate should be approached in the same way as in individuals without clefts, with a focus on the individualization of diagnosis and treatment planning.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
2015-08-26T19:19:12Z
2015-08-26T19:19:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en
Brazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014.
1677-3225
http://hdl.handle.net/11449/127326
10.1590/1677-3225v13n4a15
S1677-32252014000400319
S1677-32252014000400319.pdf
8568814008546317
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-32252014000400319&lng=en&nrm=iso&tlng=en
http://hdl.handle.net/11449/127326
identifier_str_mv Brazilian Journal of Oral Sciences, v. 13, n. 4, p. 319-324, 2014.
1677-3225
10.1590/1677-3225v13n4a15
S1677-32252014000400319
S1677-32252014000400319.pdf
8568814008546317
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Oral Sciences
0,131
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 319-324
application/pdf
dc.publisher.none.fl_str_mv Faculdade de Odontologia de Piracicaba - UNICAMP
publisher.none.fl_str_mv Faculdade de Odontologia de Piracicaba - UNICAMP
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
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instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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