Synergetic effect of silver nanoparticles and thiram on lipid bilayers

Detalhes bibliográficos
Autor(a) principal: Martin, Cibely S. [UNESP]
Data de Publicação: 2022
Outros Autores: Oliveira, Marcelo J.S. [UNESP], Maximino, Mateus D. [UNESP], Pazin, Wallance M. [UNESP], Constantino, Carlos J.L. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.molliq.2021.118406
http://hdl.handle.net/11449/233960
Resumo: The excessive concentration of nanomaterials and pesticides in industrial products, food, and in the environment can be a risk to human health. Exposure to these materials can occur through inhalation, dermal contact, or oral ingestion, which depends directly on the type of products we are exposed to. Extensive studies about the individual action of these compounds have been described. However, the effect of these mixtures (nanoparticles and pesticides, for instance) requires more investigation. Here, we evaluated by phase-contrast microscopy the individual and mixture effects of silver nanoparticles (AgNp) and thiram pesticide on mimetic systems of the lipid bilayer structure of the plasma membrane using DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) giant unilamellar vesicles (GUVs). Besides, the effect of thiram pesticide on DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) multilamellar vesicles containing AgNp (encapsulated) was also evaluated by surface-enhanced Raman scattering (SERS). The results showed a synergetic effect of the AgNp and thiram mixture, which lead to a loss of phase contrast intensity and rupture of the lipid bilayers. The synergetic effect was ascribed to the strong interaction AgNp-thiram through Ag-S bond formation.
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spelling Synergetic effect of silver nanoparticles and thiram on lipid bilayersLipid bilayerSilver nanoparticlesThiramVesiclesThe excessive concentration of nanomaterials and pesticides in industrial products, food, and in the environment can be a risk to human health. Exposure to these materials can occur through inhalation, dermal contact, or oral ingestion, which depends directly on the type of products we are exposed to. Extensive studies about the individual action of these compounds have been described. However, the effect of these mixtures (nanoparticles and pesticides, for instance) requires more investigation. Here, we evaluated by phase-contrast microscopy the individual and mixture effects of silver nanoparticles (AgNp) and thiram pesticide on mimetic systems of the lipid bilayer structure of the plasma membrane using DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) giant unilamellar vesicles (GUVs). Besides, the effect of thiram pesticide on DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) multilamellar vesicles containing AgNp (encapsulated) was also evaluated by surface-enhanced Raman scattering (SERS). The results showed a synergetic effect of the AgNp and thiram mixture, which lead to a loss of phase contrast intensity and rupture of the lipid bilayers. The synergetic effect was ascribed to the strong interaction AgNp-thiram through Ag-S bond formation.São Paulo State University (UNESP) School of Technology and Applied SciencesSão Carlos Institute of Physics Universityof São PauloSão Paulo State University (UNESP) School of Technology and Applied SciencesUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Martin, Cibely S. [UNESP]Oliveira, Marcelo J.S. [UNESP]Maximino, Mateus D. [UNESP]Pazin, Wallance M. [UNESP]Constantino, Carlos J.L. [UNESP]2022-05-01T11:54:11Z2022-05-01T11:54:11Z2022-02-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.molliq.2021.118406Journal of Molecular Liquids, v. 348.0167-7322http://hdl.handle.net/11449/23396010.1016/j.molliq.2021.1184062-s2.0-85122217037Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Molecular Liquidsinfo:eu-repo/semantics/openAccess2024-06-19T12:44:07Zoai:repositorio.unesp.br:11449/233960Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T13:47:13.319790Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Synergetic effect of silver nanoparticles and thiram on lipid bilayers
title Synergetic effect of silver nanoparticles and thiram on lipid bilayers
spellingShingle Synergetic effect of silver nanoparticles and thiram on lipid bilayers
Martin, Cibely S. [UNESP]
Lipid bilayer
Silver nanoparticles
Thiram
Vesicles
title_short Synergetic effect of silver nanoparticles and thiram on lipid bilayers
title_full Synergetic effect of silver nanoparticles and thiram on lipid bilayers
title_fullStr Synergetic effect of silver nanoparticles and thiram on lipid bilayers
title_full_unstemmed Synergetic effect of silver nanoparticles and thiram on lipid bilayers
title_sort Synergetic effect of silver nanoparticles and thiram on lipid bilayers
author Martin, Cibely S. [UNESP]
author_facet Martin, Cibely S. [UNESP]
Oliveira, Marcelo J.S. [UNESP]
Maximino, Mateus D. [UNESP]
Pazin, Wallance M. [UNESP]
Constantino, Carlos J.L. [UNESP]
author_role author
author2 Oliveira, Marcelo J.S. [UNESP]
Maximino, Mateus D. [UNESP]
Pazin, Wallance M. [UNESP]
Constantino, Carlos J.L. [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Martin, Cibely S. [UNESP]
Oliveira, Marcelo J.S. [UNESP]
Maximino, Mateus D. [UNESP]
Pazin, Wallance M. [UNESP]
Constantino, Carlos J.L. [UNESP]
dc.subject.por.fl_str_mv Lipid bilayer
Silver nanoparticles
Thiram
Vesicles
topic Lipid bilayer
Silver nanoparticles
Thiram
Vesicles
description The excessive concentration of nanomaterials and pesticides in industrial products, food, and in the environment can be a risk to human health. Exposure to these materials can occur through inhalation, dermal contact, or oral ingestion, which depends directly on the type of products we are exposed to. Extensive studies about the individual action of these compounds have been described. However, the effect of these mixtures (nanoparticles and pesticides, for instance) requires more investigation. Here, we evaluated by phase-contrast microscopy the individual and mixture effects of silver nanoparticles (AgNp) and thiram pesticide on mimetic systems of the lipid bilayer structure of the plasma membrane using DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) giant unilamellar vesicles (GUVs). Besides, the effect of thiram pesticide on DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) multilamellar vesicles containing AgNp (encapsulated) was also evaluated by surface-enhanced Raman scattering (SERS). The results showed a synergetic effect of the AgNp and thiram mixture, which lead to a loss of phase contrast intensity and rupture of the lipid bilayers. The synergetic effect was ascribed to the strong interaction AgNp-thiram through Ag-S bond formation.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-01T11:54:11Z
2022-05-01T11:54:11Z
2022-02-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.molliq.2021.118406
Journal of Molecular Liquids, v. 348.
0167-7322
http://hdl.handle.net/11449/233960
10.1016/j.molliq.2021.118406
2-s2.0-85122217037
url http://dx.doi.org/10.1016/j.molliq.2021.118406
http://hdl.handle.net/11449/233960
identifier_str_mv Journal of Molecular Liquids, v. 348.
0167-7322
10.1016/j.molliq.2021.118406
2-s2.0-85122217037
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Molecular Liquids
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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