Aspectos radiográficos e densitométricos de fraturas experimentais do radio de cães tratadas com plasma rico em plaquetas

• Autor(a) principal: Souza, Talita Floering Brêda [UNESP]
• Data de Publicação: 2011
• Outros Autores: Ferreira, Gabriel Thadeu Nogueira Martins [UNESP], Sakamoto, Silmara Sanae [UNESP], Albuquerque, Verônica Batista [UNESP], Bonfim, Suely Regina Mogami [UNESP], Andrade, Alexandre Lima de [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.15361/2175-0106.2011v27n1p001-006; http://hdl.handle.net/11449/133083
• topic: Transforming growth factor beta; Blood platelets; Bone and bones; Fator transformador de crescimento beta; Plaquetas; Osso e ossos

The present article aimed to assess bone healing of experimental radial fractures, treated or not with autologous PRP, by means of radiographic and densitometric studies. Eleven dogs were randomly allocated in two experimental groups: control group (CG n=6) PRP group (PRPG n=5). All dogs underwent radial osteotomy and osteosynthese (external skeletal fixation) of the right forelimb, in which a 2.0 mm defect was created. The gap was filled PRP in the treated group (PRPG); wile CG received no treatment. Radiographic and densitometric studies were performed immediately at the end the procedure and 14, 21, 28, 35, 45 and 60 days after the surgery (M0, M14, M21, M28, M35, M45 e M60). Way repeated measures ANOVA with Tukey as post hock test; Friedman test and Dunnís post hock test were used to compare data in different moments; and Mann-whitney test in different groups (p < 0.05). About assessment to moments; radiographc scores and densitometric values changed significantly at moment 0 and 60 within the PRPG. Comparing groups radiographic scores changed significantly from M28 and densitometric values from M45 and M60. Concluded under the conditions of this study; that PRP can be used as an adjuvant therapy to improve bone healing of experimental radial fractures (gap 2.0 mm) of dogs treated with external skeletal fixation.