Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/224248 |
Resumo: | Background and Objectives - Gynecological laparoscopy is a procedure associated to a high incidence of postoperative nausea and vomiting (PONV). This study aimed at comparing the efficacy of propofol or propofol plus dexamethasone in preventing PONV in patients submitted to gynecological laparoscopy. Methods - Forty female patients, physical status ASA I and II aged 18 to 46 years, with no previous gastric complaint, undergoing diagnostic or surgical laparoscopy were randomly distributed in 2 groups: Group 1 - patients were given 2 ml IV saline solution, while Group 2 was given intravenous dexamethasone (8 mg), before anesthetic induction. All patients were premedicated with oral midazolam (7.5 mg) and induced with sufentanil (0.5 μg.kg -1) and propofol targed controlled infusion (BIS 60), with N 2O/O 2 (F 1O 2=0.4) for maintenance. Neuromuscular block was obtained with atracurium (0.5 mg.kg -1). Postoperative analgesia consisted of ketoprofen (100 mg) and butyl-eschopolamine plus dipirone. Patients were evaluated in the PACU and in the ward after 1, 2, 3 and 12 hours after PACU discharge. Results - Both groups were identical regarding demographics data as well as surgery and anesthesia duration. One Group 1 patient referred nausea in postanesthetic care unit and in the ward, and 3 patients referred vomiting in the ward. In Group 2 no patient referred nausea and vomiting, but the difference was not statistically significant. Conclusions - Propofol or propofol plus dexamethasone were efficient in preventing PONV in patients submitted to gynecological laparoscopy. |
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Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológicaEfficacy of propofol and propofol plus dexamethasone in controlling postoperative nausea and vomiting of gynecologic laparoscopyComplications: nausea, vomitingDrugs: dexamethasoneHypnotics: propofolSurgery, Gynecological: laparoscopyBackground and Objectives - Gynecological laparoscopy is a procedure associated to a high incidence of postoperative nausea and vomiting (PONV). This study aimed at comparing the efficacy of propofol or propofol plus dexamethasone in preventing PONV in patients submitted to gynecological laparoscopy. Methods - Forty female patients, physical status ASA I and II aged 18 to 46 years, with no previous gastric complaint, undergoing diagnostic or surgical laparoscopy were randomly distributed in 2 groups: Group 1 - patients were given 2 ml IV saline solution, while Group 2 was given intravenous dexamethasone (8 mg), before anesthetic induction. All patients were premedicated with oral midazolam (7.5 mg) and induced with sufentanil (0.5 μg.kg -1) and propofol targed controlled infusion (BIS 60), with N 2O/O 2 (F 1O 2=0.4) for maintenance. Neuromuscular block was obtained with atracurium (0.5 mg.kg -1). Postoperative analgesia consisted of ketoprofen (100 mg) and butyl-eschopolamine plus dipirone. Patients were evaluated in the PACU and in the ward after 1, 2, 3 and 12 hours after PACU discharge. Results - Both groups were identical regarding demographics data as well as surgery and anesthesia duration. One Group 1 patient referred nausea in postanesthetic care unit and in the ward, and 3 patients referred vomiting in the ward. In Group 2 no patient referred nausea and vomiting, but the difference was not statistically significant. Conclusions - Propofol or propofol plus dexamethasone were efficient in preventing PONV in patients submitted to gynecological laparoscopy.CET/SBA da FMB UNESPFMB UNESPDepto de Anestesiologia da FMB UNESP, 18618-970 Botucatu, SPCET/SBA da FMB UNESPFMB UNESPDepto de Anestesiologia da FMB UNESP, 18618-970 Botucatu, SPUniversidade Estadual Paulista (UNESP)Ganem, Eliana Marisa [UNESP]Fukushima, Fernanda B. [UNESP]Medeiros Da Silva, Daniela S. [UNESP]Nakamura, Giane [UNESP]Machado Castiglia, Yara Marcondes [UNESP]Galvão Vianna, Pedro Thadeu [UNESP]2022-04-28T19:55:29Z2022-04-28T19:55:29Z2002-08-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article394-401Revista Brasileira de Anestesiologia, v. 52, n. 4, p. 394-401, 2002.0034-7094http://hdl.handle.net/11449/2242482-s2.0-0036328510Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporengRevista Brasileira de Anestesiologiainfo:eu-repo/semantics/openAccess2022-04-28T19:55:30Zoai:repositorio.unesp.br:11449/224248Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:55:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica Efficacy of propofol and propofol plus dexamethasone in controlling postoperative nausea and vomiting of gynecologic laparoscopy |
title |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
spellingShingle |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica Ganem, Eliana Marisa [UNESP] Complications: nausea, vomiting Drugs: dexamethasone Hypnotics: propofol Surgery, Gynecological: laparoscopy |
title_short |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
title_full |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
title_fullStr |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
title_full_unstemmed |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
title_sort |
Eficácia do propofol e da associação de propofol e dexametasona no controle de náusea e vômito no pós-operatório de laparoscopia ginecológica |
author |
Ganem, Eliana Marisa [UNESP] |
author_facet |
Ganem, Eliana Marisa [UNESP] Fukushima, Fernanda B. [UNESP] Medeiros Da Silva, Daniela S. [UNESP] Nakamura, Giane [UNESP] Machado Castiglia, Yara Marcondes [UNESP] Galvão Vianna, Pedro Thadeu [UNESP] |
author_role |
author |
author2 |
Fukushima, Fernanda B. [UNESP] Medeiros Da Silva, Daniela S. [UNESP] Nakamura, Giane [UNESP] Machado Castiglia, Yara Marcondes [UNESP] Galvão Vianna, Pedro Thadeu [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Ganem, Eliana Marisa [UNESP] Fukushima, Fernanda B. [UNESP] Medeiros Da Silva, Daniela S. [UNESP] Nakamura, Giane [UNESP] Machado Castiglia, Yara Marcondes [UNESP] Galvão Vianna, Pedro Thadeu [UNESP] |
dc.subject.por.fl_str_mv |
Complications: nausea, vomiting Drugs: dexamethasone Hypnotics: propofol Surgery, Gynecological: laparoscopy |
topic |
Complications: nausea, vomiting Drugs: dexamethasone Hypnotics: propofol Surgery, Gynecological: laparoscopy |
description |
Background and Objectives - Gynecological laparoscopy is a procedure associated to a high incidence of postoperative nausea and vomiting (PONV). This study aimed at comparing the efficacy of propofol or propofol plus dexamethasone in preventing PONV in patients submitted to gynecological laparoscopy. Methods - Forty female patients, physical status ASA I and II aged 18 to 46 years, with no previous gastric complaint, undergoing diagnostic or surgical laparoscopy were randomly distributed in 2 groups: Group 1 - patients were given 2 ml IV saline solution, while Group 2 was given intravenous dexamethasone (8 mg), before anesthetic induction. All patients were premedicated with oral midazolam (7.5 mg) and induced with sufentanil (0.5 μg.kg -1) and propofol targed controlled infusion (BIS 60), with N 2O/O 2 (F 1O 2=0.4) for maintenance. Neuromuscular block was obtained with atracurium (0.5 mg.kg -1). Postoperative analgesia consisted of ketoprofen (100 mg) and butyl-eschopolamine plus dipirone. Patients were evaluated in the PACU and in the ward after 1, 2, 3 and 12 hours after PACU discharge. Results - Both groups were identical regarding demographics data as well as surgery and anesthesia duration. One Group 1 patient referred nausea in postanesthetic care unit and in the ward, and 3 patients referred vomiting in the ward. In Group 2 no patient referred nausea and vomiting, but the difference was not statistically significant. Conclusions - Propofol or propofol plus dexamethasone were efficient in preventing PONV in patients submitted to gynecological laparoscopy. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-08-14 2022-04-28T19:55:29Z 2022-04-28T19:55:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Revista Brasileira de Anestesiologia, v. 52, n. 4, p. 394-401, 2002. 0034-7094 http://hdl.handle.net/11449/224248 2-s2.0-0036328510 |
identifier_str_mv |
Revista Brasileira de Anestesiologia, v. 52, n. 4, p. 394-401, 2002. 0034-7094 2-s2.0-0036328510 |
url |
http://hdl.handle.net/11449/224248 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
Revista Brasileira de Anestesiologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
394-401 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803046872042962944 |