O uso de drogas anticoagulantes e antiplaquetárias orais em pacientes cirúrgico-ambulatoriais: revisão de literatura

• Autor(a) principal: Brambilla, Talita Gomes [UNESP]
• Data de Publicação: 2010
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/149426; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2017-01-26/000855204.pdf
• topic: Cirurgia bucal; Anticoagulantes; Hemostasia; Surgery, Oral

Oral anticoagulants (AOC) and antiplatelet drugs are used for prevention of thromboembolic events such as pulmonary thromboembolism in patients with atrial fribrilação and / or heart valves, thrombosis and pulmonary embolism, it is considered vitamin K antagonists. The most known and widely used, warfarin sodium that acts by inhibiting or antagonizing factors II, VII, IX and X coagulation, vitamin K-dependent, and the anticoagulant proteins C and S, and aspirin that inhibits platelet aggregation. For dental patients indicated surgical procedures were asked to discontinue the use of anticoagulants, until the INR value remained ≥ 2.0 that in order to prevent bleeding during the surgery and postoperative. However, the interruption of the AOC can cause the formation of a blood clot leading to obstruction of the blood. Thus, it was doubtful whether the discontinuation of the drug to perform minor surgery, in which local hemostatic measures would be sufficient to stop blood flow. Thus the main purpose was to assess the risk of bleeding in patients using local AOC who undergo surgical procedures, through a literature review of relevant clinical trials published between 1990 and 2010, the Medline / Pubmed. In this literature review concluded, based on evidence from studies reported that the benefit of preventing thromboembolism outweighs the risk of bleeding, therefore, it is recommended to keep the dose of anticoagulant therapy unchanged for patients undergoing minor oral surgery and Implant Dentistry, working with therapeutic INR levels, and adopt local hemostatic measures - such as the use of antifibrinolytic agents, gels, compresses. Moreover, an accurate surgical technique should be performed in these patients. With respect to oral surgery more invasive with a risk of bleeding may be a need for treatment in conjunction with a medical team