Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.foodchem.2021.131019 http://hdl.handle.net/11449/233513 |
Resumo: | Pleurotus is an edible mushroom from the well-known genus of Basidiomycetes; it is the second-most commonly consumed mushroom worldwide. This genus is characterized by the presence of steroids, fatty acids, and polysaccharides. Recently, Pleurotus has become popular as a functional food owing to its health benefits, primarily because they are a source of vitamins, fibers, minerals, and lipids. In natural products chemistry, dereplication techniques identify bioactive molecules from natural sources such as plants and fungi without isolating or characterizing molecules. We used dereplication techniques aided by the Global Natural Products Social Molecular Network to analyze the chemical composition of the methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus, and P. pulmonarius), to identify bioactive molecules with nutraceutical properties. Using this technique, we identified several molecular families, including eight fatty acids and seven steroids. Our findings suggest that dereplication is a relatively rapid tool for characterizing fungal species and determining their nutraceutical value. |
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Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approachBasidiomycetesFatty acidGNPSNutraceutical valueSteroidPleurotus is an edible mushroom from the well-known genus of Basidiomycetes; it is the second-most commonly consumed mushroom worldwide. This genus is characterized by the presence of steroids, fatty acids, and polysaccharides. Recently, Pleurotus has become popular as a functional food owing to its health benefits, primarily because they are a source of vitamins, fibers, minerals, and lipids. In natural products chemistry, dereplication techniques identify bioactive molecules from natural sources such as plants and fungi without isolating or characterizing molecules. We used dereplication techniques aided by the Global Natural Products Social Molecular Network to analyze the chemical composition of the methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus, and P. pulmonarius), to identify bioactive molecules with nutraceutical properties. Using this technique, we identified several molecular families, including eight fatty acids and seven steroids. Our findings suggest that dereplication is a relatively rapid tool for characterizing fungal species and determining their nutraceutical value.Instituto de Ciências Ambientais Químicas e Farmacêuticas Universidade Federal de São PauloFaculdade de Ciências Agrarias e Tecnológicas Universidade Estadual Paulista Júlio de Mesquita FilhoFaculdade de Ciências Agrarias e Tecnológicas Universidade Estadual Paulista Júlio de Mesquita FilhoUniversidade Federal de São Paulo (UNIFESP)Universidade Estadual Paulista (UNESP)Caldas, Lhaís AraújoZied, Diego Cunha [UNESP]Sartorelli, Patrícia2022-05-01T09:00:52Z2022-05-01T09:00:52Z2022-02-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.foodchem.2021.131019Food Chemistry, v. 370.1873-70720308-8146http://hdl.handle.net/11449/23351310.1016/j.foodchem.2021.1310192-s2.0-85114512754Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFood Chemistryinfo:eu-repo/semantics/openAccess2024-05-07T13:48:06Zoai:repositorio.unesp.br:11449/233513Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:21:07.687385Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
title |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
spellingShingle |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach Caldas, Lhaís Araújo Basidiomycetes Fatty acid GNPS Nutraceutical value Steroid |
title_short |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
title_full |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
title_fullStr |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
title_full_unstemmed |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
title_sort |
Dereplication of extracts from nutraceutical mushrooms pleurotus using molecular network approach |
author |
Caldas, Lhaís Araújo |
author_facet |
Caldas, Lhaís Araújo Zied, Diego Cunha [UNESP] Sartorelli, Patrícia |
author_role |
author |
author2 |
Zied, Diego Cunha [UNESP] Sartorelli, Patrícia |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Caldas, Lhaís Araújo Zied, Diego Cunha [UNESP] Sartorelli, Patrícia |
dc.subject.por.fl_str_mv |
Basidiomycetes Fatty acid GNPS Nutraceutical value Steroid |
topic |
Basidiomycetes Fatty acid GNPS Nutraceutical value Steroid |
description |
Pleurotus is an edible mushroom from the well-known genus of Basidiomycetes; it is the second-most commonly consumed mushroom worldwide. This genus is characterized by the presence of steroids, fatty acids, and polysaccharides. Recently, Pleurotus has become popular as a functional food owing to its health benefits, primarily because they are a source of vitamins, fibers, minerals, and lipids. In natural products chemistry, dereplication techniques identify bioactive molecules from natural sources such as plants and fungi without isolating or characterizing molecules. We used dereplication techniques aided by the Global Natural Products Social Molecular Network to analyze the chemical composition of the methanolic extracts of six Pleurotus species (P. sapidus, P. ostreaus, P. ostreaus var. Florida, P. djamor, P. citrinopileatus, and P. pulmonarius), to identify bioactive molecules with nutraceutical properties. Using this technique, we identified several molecular families, including eight fatty acids and seven steroids. Our findings suggest that dereplication is a relatively rapid tool for characterizing fungal species and determining their nutraceutical value. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-01T09:00:52Z 2022-05-01T09:00:52Z 2022-02-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.foodchem.2021.131019 Food Chemistry, v. 370. 1873-7072 0308-8146 http://hdl.handle.net/11449/233513 10.1016/j.foodchem.2021.131019 2-s2.0-85114512754 |
url |
http://dx.doi.org/10.1016/j.foodchem.2021.131019 http://hdl.handle.net/11449/233513 |
identifier_str_mv |
Food Chemistry, v. 370. 1873-7072 0308-8146 10.1016/j.foodchem.2021.131019 2-s2.0-85114512754 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Food Chemistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129509687296000 |