Efeitos do plasma rico em plaquetas, do laser de baixa intensidade ou da associação de ambos na regeneração óssea: uma revisão de literatura

• Autor(a) principal: Santinoni, Carolina dos Santos [UNESP]
• Data de Publicação: 2009
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/156231; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2018-01-15/000893826.pdf
• topic: Regeneração óssea; Plaquetas; Substâncias de crescimento; Bone regeneration

Researchers continuously strive to improve bone grafting techniques and to provide means to obtain a faster and denser bone regeneration. At present, bone reconstruction can be obtained by the application of either physical (ultra-sound, electromagnetic fields, laser) or chemical stimulus (biomaterials, growth factors). Among the physical stimulus, a technique that has been extensively studied lately is the use of laser. The lasers can be classified as surgical (high power) and non-surgical (low-power) for therapeutic purposes. Low level lasers therapy (LLLT) is widely used to stimulate tissues and improve wound repair. With regard to chemical stimulus used for improving bone regeneration, the Platelet-Rich Plasma (PRP) has been largely used. The rationale behind the use of PRP is the assumption that it may improve wound healing by increasing the levels of growth factors in the wound site after degranulation of the platelets. It is important to emphasize that clinical and animal studies have yielded contradictory results with regard to the effect of PRP on bone healing. The use of the low level laser as a tissue biostimulation agent is also controversial, mainly with regard to mineralized tissues. The purpose of this study was to review the present available evidences that support the use of PRP and LLLT to enhance bone regeneration, as well as to discuss the rationale to combine both therapies for regenerative procedures