Femtosecond laser patterning of the biopolymer chitosan for biofilm formation
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
DOI: | 10.3390/ijms17081243 |
Texto Completo: | http://dx.doi.org/10.3390/ijms17081243 http://hdl.handle.net/11449/173390 |
Resumo: | Controlling microbial growth is crucial for many biomedical, pharmaceutical and food industry applications. In this paper, we used a femtosecond laser to microstructure the surface of chitosan, a biocompatible polymer that has been explored for applications ranging from antimicrobial action to drug delivery. The influence of energy density on the features produced on chitosan was investigated by optical and atomic force microscopies. An increase in the hydrophilic character of the chitosan surface was attained upon laser micromachining. Patterned chitosan films were used to observe Staphylococcus aureus (ATCC 25923) biofilm formation, revealing an increase in the biofilm formation in the structured regions. Our results indicate that fs-laser micromachining is an attractive option to pattern biocompatible surfaces, and to investigate basic aspects of the relationship between surface topography and bacterial adhesion. |
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Repositório Institucional da UNESP |
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Femtosecond laser patterning of the biopolymer chitosan for biofilm formationBacterial growthChitosanFs-laser micromachiningMicropatterningControlling microbial growth is crucial for many biomedical, pharmaceutical and food industry applications. In this paper, we used a femtosecond laser to microstructure the surface of chitosan, a biocompatible polymer that has been explored for applications ranging from antimicrobial action to drug delivery. The influence of energy density on the features produced on chitosan was investigated by optical and atomic force microscopies. An increase in the hydrophilic character of the chitosan surface was attained upon laser micromachining. Patterned chitosan films were used to observe Staphylococcus aureus (ATCC 25923) biofilm formation, revealing an increase in the biofilm formation in the structured regions. Our results indicate that fs-laser micromachining is an attractive option to pattern biocompatible surfaces, and to investigate basic aspects of the relationship between surface topography and bacterial adhesion.São Carlos Institute of Physics University of São Paulo (USP)Department of Materials Engineering School of Engineering of São Carlos (USP)Physics Department Federal University of São Carlos (UFSCAR)Faculdade de Ciencias Farmaceuticas UNESP—Univ. Estadual Paulista Departamento de Analises Clinicas, Campus AraraquaraFaculdade de Ciencias Farmaceuticas UNESP—Univ. Estadual Paulista Departamento de Analises Clinicas, Campus AraraquaraUniversidade de São Paulo (USP)Universidade Federal de São Carlos (UFSCar)Universidade Estadual Paulista (Unesp)Estevam-Alves, ReginaFerreira, Paulo Henrique DiasCoatrini, Andrey C.Oliveira, Osvaldo N.Fontana, Carla Raquel [UNESP]Mendonca, Cleber Renato2018-12-11T17:04:57Z2018-12-11T17:04:57Z2016-08-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.3390/ijms17081243International Journal of Molecular Sciences, v. 17, n. 8, 2016.1422-00671661-6596http://hdl.handle.net/11449/17339010.3390/ijms170812432-s2.0-849834229182-s2.0-84983422918.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Molecular Sciences1,260info:eu-repo/semantics/openAccess2024-06-21T15:19:30Zoai:repositorio.unesp.br:11449/173390Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:14:19.661488Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
title |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
spellingShingle |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation Femtosecond laser patterning of the biopolymer chitosan for biofilm formation Estevam-Alves, Regina Bacterial growth Chitosan Fs-laser micromachining Micropatterning Estevam-Alves, Regina Bacterial growth Chitosan Fs-laser micromachining Micropatterning |
title_short |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
title_full |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
title_fullStr |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
title_full_unstemmed |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
title_sort |
Femtosecond laser patterning of the biopolymer chitosan for biofilm formation |
author |
Estevam-Alves, Regina |
author_facet |
Estevam-Alves, Regina Estevam-Alves, Regina Ferreira, Paulo Henrique Dias Coatrini, Andrey C. Oliveira, Osvaldo N. Fontana, Carla Raquel [UNESP] Mendonca, Cleber Renato Ferreira, Paulo Henrique Dias Coatrini, Andrey C. Oliveira, Osvaldo N. Fontana, Carla Raquel [UNESP] Mendonca, Cleber Renato |
author_role |
author |
author2 |
Ferreira, Paulo Henrique Dias Coatrini, Andrey C. Oliveira, Osvaldo N. Fontana, Carla Raquel [UNESP] Mendonca, Cleber Renato |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Federal de São Carlos (UFSCar) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Estevam-Alves, Regina Ferreira, Paulo Henrique Dias Coatrini, Andrey C. Oliveira, Osvaldo N. Fontana, Carla Raquel [UNESP] Mendonca, Cleber Renato |
dc.subject.por.fl_str_mv |
Bacterial growth Chitosan Fs-laser micromachining Micropatterning |
topic |
Bacterial growth Chitosan Fs-laser micromachining Micropatterning |
description |
Controlling microbial growth is crucial for many biomedical, pharmaceutical and food industry applications. In this paper, we used a femtosecond laser to microstructure the surface of chitosan, a biocompatible polymer that has been explored for applications ranging from antimicrobial action to drug delivery. The influence of energy density on the features produced on chitosan was investigated by optical and atomic force microscopies. An increase in the hydrophilic character of the chitosan surface was attained upon laser micromachining. Patterned chitosan films were used to observe Staphylococcus aureus (ATCC 25923) biofilm formation, revealing an increase in the biofilm formation in the structured regions. Our results indicate that fs-laser micromachining is an attractive option to pattern biocompatible surfaces, and to investigate basic aspects of the relationship between surface topography and bacterial adhesion. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-08-19 2018-12-11T17:04:57Z 2018-12-11T17:04:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/ijms17081243 International Journal of Molecular Sciences, v. 17, n. 8, 2016. 1422-0067 1661-6596 http://hdl.handle.net/11449/173390 10.3390/ijms17081243 2-s2.0-84983422918 2-s2.0-84983422918.pdf |
url |
http://dx.doi.org/10.3390/ijms17081243 http://hdl.handle.net/11449/173390 |
identifier_str_mv |
International Journal of Molecular Sciences, v. 17, n. 8, 2016. 1422-0067 1661-6596 10.3390/ijms17081243 2-s2.0-84983422918 2-s2.0-84983422918.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of Molecular Sciences 1,260 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1822182581553070080 |
dc.identifier.doi.none.fl_str_mv |
10.3390/ijms17081243 |