Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1136/jclinpath-2015-203325 http://hdl.handle.net/11449/164716 |
Resumo: | Aims To detect the presence of Epstein-Barr virus (EBV) DNA in different sources of materials from a matched group of patients with oral lichen planus (OLP) and a group of people without OLP lesions, and to correlate the presence of virus with epidemiological variables of the groups studied. Methods Fresh tissue samples, saliva, exfoliated cells and plasma of 24 patients with OLP lesions (cases) and 17 patients without OLP lesions (controls) were collected. EBV was detected by nested PCR. Results Viral positivity was obtained in 62.5% of tissue samples; in 70.8% of exfoliated cell samples; in 33.3% of blood plasma samples and in 75% of saliva samples in the cases; and in 35.3% of tissue samples; 82.4% of exfoliated cell samples; in 47.1% of blood plasma samples and in 64.7% of saliva samples in the controls. There was a predominance of women in both groups. Variables not atrophic-erosive were most affected by EBV. Conclusions No relationship between EBV and OLP was found. However, all sources tested in this study were considered suitable for the detection of viruses. |
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spelling |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control studyAims To detect the presence of Epstein-Barr virus (EBV) DNA in different sources of materials from a matched group of patients with oral lichen planus (OLP) and a group of people without OLP lesions, and to correlate the presence of virus with epidemiological variables of the groups studied. Methods Fresh tissue samples, saliva, exfoliated cells and plasma of 24 patients with OLP lesions (cases) and 17 patients without OLP lesions (controls) were collected. EBV was detected by nested PCR. Results Viral positivity was obtained in 62.5% of tissue samples; in 70.8% of exfoliated cell samples; in 33.3% of blood plasma samples and in 75% of saliva samples in the cases; and in 35.3% of tissue samples; 82.4% of exfoliated cell samples; in 47.1% of blood plasma samples and in 64.7% of saliva samples in the controls. There was a predominance of women in both groups. Variables not atrophic-erosive were most affected by EBV. Conclusions No relationship between EBV and OLP was found. However, all sources tested in this study were considered suitable for the detection of viruses.Aracatuba Sch Dent, Oral Oncol Ctr, Aracatuba, SP, BrazilAracatuba Sch Dent, Dept Pathol & Clin Propaedeut, Aracatuba, SP, BrazilAracatuba Sch Vet Med, Anim Hlth & Prod, Aracatuba, SP, BrazilBmj Publishing GroupAracatuba Sch DentAracatuba Sch Vet MedUniversidade Estadual Paulista (Unesp)Vieira, Rubia da RochaFerreira, Ligia LavezoBiasoli, Eder RicardoBernabe, Daniel GaleraNunes, Caris MaroniMiyahara, Glauco Issamu2018-11-26T17:55:48Z2018-11-26T17:55:48Z2016-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article358-363application/pdfhttp://dx.doi.org/10.1136/jclinpath-2015-203325Journal Of Clinical Pathology. London: Bmj Publishing Group, v. 69, n. 4, p. 358-363, 2016.0021-9746http://hdl.handle.net/11449/16471610.1136/jclinpath-2015-203325WOS:000372466400012WOS000372466400012.pdf38468911670832110000-0002-5326-2026Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of Clinical Pathology1,050info:eu-repo/semantics/openAccess2024-09-04T19:15:52Zoai:repositorio.unesp.br:11449/164716Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T19:15:52Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
title |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
spellingShingle |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study Vieira, Rubia da Rocha |
title_short |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
title_full |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
title_fullStr |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
title_full_unstemmed |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
title_sort |
Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study |
author |
Vieira, Rubia da Rocha |
author_facet |
Vieira, Rubia da Rocha Ferreira, Ligia Lavezo Biasoli, Eder Ricardo Bernabe, Daniel Galera Nunes, Caris Maroni Miyahara, Glauco Issamu |
author_role |
author |
author2 |
Ferreira, Ligia Lavezo Biasoli, Eder Ricardo Bernabe, Daniel Galera Nunes, Caris Maroni Miyahara, Glauco Issamu |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Aracatuba Sch Dent Aracatuba Sch Vet Med Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Vieira, Rubia da Rocha Ferreira, Ligia Lavezo Biasoli, Eder Ricardo Bernabe, Daniel Galera Nunes, Caris Maroni Miyahara, Glauco Issamu |
description |
Aims To detect the presence of Epstein-Barr virus (EBV) DNA in different sources of materials from a matched group of patients with oral lichen planus (OLP) and a group of people without OLP lesions, and to correlate the presence of virus with epidemiological variables of the groups studied. Methods Fresh tissue samples, saliva, exfoliated cells and plasma of 24 patients with OLP lesions (cases) and 17 patients without OLP lesions (controls) were collected. EBV was detected by nested PCR. Results Viral positivity was obtained in 62.5% of tissue samples; in 70.8% of exfoliated cell samples; in 33.3% of blood plasma samples and in 75% of saliva samples in the cases; and in 35.3% of tissue samples; 82.4% of exfoliated cell samples; in 47.1% of blood plasma samples and in 64.7% of saliva samples in the controls. There was a predominance of women in both groups. Variables not atrophic-erosive were most affected by EBV. Conclusions No relationship between EBV and OLP was found. However, all sources tested in this study were considered suitable for the detection of viruses. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-04-01 2018-11-26T17:55:48Z 2018-11-26T17:55:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1136/jclinpath-2015-203325 Journal Of Clinical Pathology. London: Bmj Publishing Group, v. 69, n. 4, p. 358-363, 2016. 0021-9746 http://hdl.handle.net/11449/164716 10.1136/jclinpath-2015-203325 WOS:000372466400012 WOS000372466400012.pdf 3846891167083211 0000-0002-5326-2026 |
url |
http://dx.doi.org/10.1136/jclinpath-2015-203325 http://hdl.handle.net/11449/164716 |
identifier_str_mv |
Journal Of Clinical Pathology. London: Bmj Publishing Group, v. 69, n. 4, p. 358-363, 2016. 0021-9746 10.1136/jclinpath-2015-203325 WOS:000372466400012 WOS000372466400012.pdf 3846891167083211 0000-0002-5326-2026 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal Of Clinical Pathology 1,050 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
358-363 application/pdf |
dc.publisher.none.fl_str_mv |
Bmj Publishing Group |
publisher.none.fl_str_mv |
Bmj Publishing Group |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021405790568448 |