Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.36660/abc.20210386 http://hdl.handle.net/11449/240488 |
Resumo: | Background: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up. |
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Repositório Institucional da UNESP |
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Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery DiseaseArterial PressureCardiovascular SystemExercisePeripheral Arterial DiseaseBackground: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up.Hospital Israelita Albert Einstein Instituto de Educação e Pesquisa,1, SPUniversidade Nove de Julho Programa de Pós-graduação em Medicina, SPUniversidade Federal Rural de Pernambuco, PEUniversidade Estadual Paulista Júlio de Mesquita Filho, SPNorthumbria UniversityUniversidade Estadual Paulista Júlio de Mesquita Filho, SPInstituto de Educação e Pesquisa,1Programa de Pós-graduação em MedicinaUniversidade Federal Rural de PernambucoUniversidade Estadual Paulista (UNESP)Northumbria UniversityMonteiro, FranciellyCucato, Gabriel GrizzoCorreia, Marilia de AlmeidaOliveira, Paulo Mesquita Longano deRitti-Dias, Raphael MendesFarah, Breno QuintellaChristofaro, Diego Giuliano Destro [UNESP]2023-03-01T20:19:12Z2023-03-01T20:19:12Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article59-66http://dx.doi.org/10.36660/abc.20210386Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022.1678-41700066-782Xhttp://hdl.handle.net/11449/24048810.36660/abc.202103862-s2.0-85134432727Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos Brasileiros de Cardiologiainfo:eu-repo/semantics/openAccess2023-03-01T20:19:13Zoai:repositorio.unesp.br:11449/240488Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:06:02.328230Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
title |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
spellingShingle |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease Monteiro, Francielly Arterial Pressure Cardiovascular System Exercise Peripheral Arterial Disease |
title_short |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
title_full |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
title_fullStr |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
title_full_unstemmed |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
title_sort |
Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease |
author |
Monteiro, Francielly |
author_facet |
Monteiro, Francielly Cucato, Gabriel Grizzo Correia, Marilia de Almeida Oliveira, Paulo Mesquita Longano de Ritti-Dias, Raphael Mendes Farah, Breno Quintella Christofaro, Diego Giuliano Destro [UNESP] |
author_role |
author |
author2 |
Cucato, Gabriel Grizzo Correia, Marilia de Almeida Oliveira, Paulo Mesquita Longano de Ritti-Dias, Raphael Mendes Farah, Breno Quintella Christofaro, Diego Giuliano Destro [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Instituto de Educação e Pesquisa,1 Programa de Pós-graduação em Medicina Universidade Federal Rural de Pernambuco Universidade Estadual Paulista (UNESP) Northumbria University |
dc.contributor.author.fl_str_mv |
Monteiro, Francielly Cucato, Gabriel Grizzo Correia, Marilia de Almeida Oliveira, Paulo Mesquita Longano de Ritti-Dias, Raphael Mendes Farah, Breno Quintella Christofaro, Diego Giuliano Destro [UNESP] |
dc.subject.por.fl_str_mv |
Arterial Pressure Cardiovascular System Exercise Peripheral Arterial Disease |
topic |
Arterial Pressure Cardiovascular System Exercise Peripheral Arterial Disease |
description |
Background: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 2023-03-01T20:19:12Z 2023-03-01T20:19:12Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.36660/abc.20210386 Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022. 1678-4170 0066-782X http://hdl.handle.net/11449/240488 10.36660/abc.20210386 2-s2.0-85134432727 |
url |
http://dx.doi.org/10.36660/abc.20210386 http://hdl.handle.net/11449/240488 |
identifier_str_mv |
Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022. 1678-4170 0066-782X 10.36660/abc.20210386 2-s2.0-85134432727 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
59-66 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128315329871872 |