Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease

Detalhes bibliográficos
Autor(a) principal: Monteiro, Francielly
Data de Publicação: 2022
Outros Autores: Cucato, Gabriel Grizzo, Correia, Marilia de Almeida, Oliveira, Paulo Mesquita Longano de, Ritti-Dias, Raphael Mendes, Farah, Breno Quintella, Christofaro, Diego Giuliano Destro [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.36660/abc.20210386
http://hdl.handle.net/11449/240488
Resumo: Background: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up.
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spelling Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery DiseaseArterial PressureCardiovascular SystemExercisePeripheral Arterial DiseaseBackground: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up.Hospital Israelita Albert Einstein Instituto de Educação e Pesquisa,1, SPUniversidade Nove de Julho Programa de Pós-graduação em Medicina, SPUniversidade Federal Rural de Pernambuco, PEUniversidade Estadual Paulista Júlio de Mesquita Filho, SPNorthumbria UniversityUniversidade Estadual Paulista Júlio de Mesquita Filho, SPInstituto de Educação e Pesquisa,1Programa de Pós-graduação em MedicinaUniversidade Federal Rural de PernambucoUniversidade Estadual Paulista (UNESP)Northumbria UniversityMonteiro, FranciellyCucato, Gabriel GrizzoCorreia, Marilia de AlmeidaOliveira, Paulo Mesquita Longano deRitti-Dias, Raphael MendesFarah, Breno QuintellaChristofaro, Diego Giuliano Destro [UNESP]2023-03-01T20:19:12Z2023-03-01T20:19:12Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article59-66http://dx.doi.org/10.36660/abc.20210386Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022.1678-41700066-782Xhttp://hdl.handle.net/11449/24048810.36660/abc.202103862-s2.0-85134432727Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos Brasileiros de Cardiologiainfo:eu-repo/semantics/openAccess2023-03-01T20:19:13Zoai:repositorio.unesp.br:11449/240488Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:06:02.328230Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
title Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
spellingShingle Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
Monteiro, Francielly
Arterial Pressure
Cardiovascular System
Exercise
Peripheral Arterial Disease
title_short Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
title_full Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
title_fullStr Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
title_full_unstemmed Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
title_sort Longitudinal Changes in Physical Activity Levels and Cardiovascular Risk Parameters in Patients with Symptomatic Peripheral Artery Disease
author Monteiro, Francielly
author_facet Monteiro, Francielly
Cucato, Gabriel Grizzo
Correia, Marilia de Almeida
Oliveira, Paulo Mesquita Longano de
Ritti-Dias, Raphael Mendes
Farah, Breno Quintella
Christofaro, Diego Giuliano Destro [UNESP]
author_role author
author2 Cucato, Gabriel Grizzo
Correia, Marilia de Almeida
Oliveira, Paulo Mesquita Longano de
Ritti-Dias, Raphael Mendes
Farah, Breno Quintella
Christofaro, Diego Giuliano Destro [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Educação e Pesquisa,1
Programa de Pós-graduação em Medicina
Universidade Federal Rural de Pernambuco
Universidade Estadual Paulista (UNESP)
Northumbria University
dc.contributor.author.fl_str_mv Monteiro, Francielly
Cucato, Gabriel Grizzo
Correia, Marilia de Almeida
Oliveira, Paulo Mesquita Longano de
Ritti-Dias, Raphael Mendes
Farah, Breno Quintella
Christofaro, Diego Giuliano Destro [UNESP]
dc.subject.por.fl_str_mv Arterial Pressure
Cardiovascular System
Exercise
Peripheral Arterial Disease
topic Arterial Pressure
Cardiovascular System
Exercise
Peripheral Arterial Disease
description Background: Previous cross-sectional studies have demonstrated that physical activity is associated with lower cardiovascular risk in patients with peripheral artery disease (PAD). However, it is not possible to establish causality, and longitudinal design studies are required. Objective: To analyze the changes in cardiovascular risk parameters and physical activity levels after a 2-year follow-up in patients with symptomatic PAD. Methods: This study started in 2015. In the first phase, 268 patients were included. In the second phase, after 2 years (median = 26 months), 72 patients were re-evaluated. Cardiovascular risk parameters, such as blood pressure, cardiac autonomic modulation, and arterial stiffness, and physical activity levels were measured at baseline and after 2 years of follow-up. Association among delta changes (values from follow-up – baseline) in physical activity and cardiovascular parameters were analyzed by multiple linear regression. The significance level was set at p < 0.05. Results: Patients reduced their total physical activity levels compared to baseline (baseline = 2257.6 ± 774.5 versus follow-up = 2041 ± 676.2 min/week, p = 0.001). After follow-up, ankle-brachial index (0.62 ± 0.20 versus 0.54 ± 0.20, p = 0.003), and standard deviation of all RR intervals (43.4 ± 27.0 versus 25.1 ± 13.4 ms, p < 0.001) were lower, whereas carotid-femoral pulse wave velocity was higher (9.0 ± 3.0 versus 10.7 ± 3.4 m/s, p = 0.002) compared to baseline values. We did not observe any association among delta values of physical activity levels and cardiovascular risk parameters. Conclusion: Patients with PAD had reduced physical activity levels and impaired cardiovascular risk parameters during 2-year follow-up.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
2023-03-01T20:19:12Z
2023-03-01T20:19:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.36660/abc.20210386
Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022.
1678-4170
0066-782X
http://hdl.handle.net/11449/240488
10.36660/abc.20210386
2-s2.0-85134432727
url http://dx.doi.org/10.36660/abc.20210386
http://hdl.handle.net/11449/240488
identifier_str_mv Arquivos Brasileiros de Cardiologia, v. 119, n. 1, p. 59-66, 2022.
1678-4170
0066-782X
10.36660/abc.20210386
2-s2.0-85134432727
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos Brasileiros de Cardiologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 59-66
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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