Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas.
Main Author: | |
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Publication Date: | 1994 |
Other Authors: | , , , |
Format: | Article |
Language: | por |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1590/S0037-86821994000300003 http://hdl.handle.net/11449/64488 |
Summary: | This study was designed to evaluate retrospectively the frequency and etiology of the gastrointestinal (GI) lesions in 45 consecutive necropsies of adult patients with Acquired Immunodeficiency Syndrome (AIDS). Gross descriptions and histological sections of the GI tract, from mouth to anus, were reviewed. The slides were H&E stained, and when necessary special stains and immunohistochemical methods were also employed. There were lesions in GI tract in 37 (82.3%) patients; the mouth was the segment most frequently involved (73.3% of the cases), followed by the colon (55.5%). Multiple lesions occurred in 17 (37.7%) cases. Cytomegalovirus caused colonic lesions in 35.7% of the cases. Candidiasis was observed in 26.6% mainly in the mouth and herpes simplex (8.8%) was the important agent of esophageal lesions. Oral hairy leukoplasia associated with HPV was found in 16 (35.5%) cases. Neoplasia was diagnosed in 7 (15.5%) cases: four Kaposi's sarcoma, two anal intramucosal carcinomas and one gastric lymphoma. Our data confirm the high frequency and variety of GI tract alterations in AIDS. |
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Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas.Lesions of the gastrointestinal tract in acquired immunodeficiency syndrome: study of 45 consecutive necropsiesacquired immune deficiency syndromeadultautopsyfemalegastrointestinal diseasehumanmalepathologyretrospective studyAcquired Immunodeficiency SyndromeAdultAutopsyEnglish AbstractFemaleGastrointestinal DiseasesHumanMaleMiddle AgeRetrospective StudiesThis study was designed to evaluate retrospectively the frequency and etiology of the gastrointestinal (GI) lesions in 45 consecutive necropsies of adult patients with Acquired Immunodeficiency Syndrome (AIDS). Gross descriptions and histological sections of the GI tract, from mouth to anus, were reviewed. The slides were H&E stained, and when necessary special stains and immunohistochemical methods were also employed. There were lesions in GI tract in 37 (82.3%) patients; the mouth was the segment most frequently involved (73.3% of the cases), followed by the colon (55.5%). Multiple lesions occurred in 17 (37.7%) cases. Cytomegalovirus caused colonic lesions in 35.7% of the cases. Candidiasis was observed in 26.6% mainly in the mouth and herpes simplex (8.8%) was the important agent of esophageal lesions. Oral hairy leukoplasia associated with HPV was found in 16 (35.5%) cases. Neoplasia was diagnosed in 7 (15.5%) cases: four Kaposi's sarcoma, two anal intramucosal carcinomas and one gastric lymphoma. Our data confirm the high frequency and variety of GI tract alterations in AIDS.Universidade Estadual Paulista (Unesp)de Carvalho, M. G.Rodrigues, M. A.Marques, M. E.Franco, M.Montenegro, M. R.2014-05-27T11:17:57Z2014-05-27T11:17:57Z1994-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article135-141application/pdfhttp://dx.doi.org/10.1590/S0037-86821994000300003Revista da Sociedade Brasileira de Medicina Tropical, v. 27, n. 3, p. 135-141, 1994.0037-8682http://hdl.handle.net/11449/6448810.1590/S0037-86821994000300003S0037-868219940003000032-s2.0-00284740542-s2.0-0028474054.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista da Sociedade Brasileira de Medicina Tropical1.3580,658info:eu-repo/semantics/openAccess2024-01-01T06:24:07Zoai:repositorio.unesp.br:11449/64488Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-01T06:24:07Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. Lesions of the gastrointestinal tract in acquired immunodeficiency syndrome: study of 45 consecutive necropsies |
title |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
spellingShingle |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. de Carvalho, M. G. acquired immune deficiency syndrome adult autopsy female gastrointestinal disease human male pathology retrospective study Acquired Immunodeficiency Syndrome Adult Autopsy English Abstract Female Gastrointestinal Diseases Human Male Middle Age Retrospective Studies |
title_short |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
title_full |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
title_fullStr |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
title_full_unstemmed |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
title_sort |
Lesões do trato gastrointestinal na síndrome da imunodeficiência adquirida: estudo de 45 necrópsias consecutivas. |
author |
de Carvalho, M. G. |
author_facet |
de Carvalho, M. G. Rodrigues, M. A. Marques, M. E. Franco, M. Montenegro, M. R. |
author_role |
author |
author2 |
Rodrigues, M. A. Marques, M. E. Franco, M. Montenegro, M. R. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
de Carvalho, M. G. Rodrigues, M. A. Marques, M. E. Franco, M. Montenegro, M. R. |
dc.subject.por.fl_str_mv |
acquired immune deficiency syndrome adult autopsy female gastrointestinal disease human male pathology retrospective study Acquired Immunodeficiency Syndrome Adult Autopsy English Abstract Female Gastrointestinal Diseases Human Male Middle Age Retrospective Studies |
topic |
acquired immune deficiency syndrome adult autopsy female gastrointestinal disease human male pathology retrospective study Acquired Immunodeficiency Syndrome Adult Autopsy English Abstract Female Gastrointestinal Diseases Human Male Middle Age Retrospective Studies |
description |
This study was designed to evaluate retrospectively the frequency and etiology of the gastrointestinal (GI) lesions in 45 consecutive necropsies of adult patients with Acquired Immunodeficiency Syndrome (AIDS). Gross descriptions and histological sections of the GI tract, from mouth to anus, were reviewed. The slides were H&E stained, and when necessary special stains and immunohistochemical methods were also employed. There were lesions in GI tract in 37 (82.3%) patients; the mouth was the segment most frequently involved (73.3% of the cases), followed by the colon (55.5%). Multiple lesions occurred in 17 (37.7%) cases. Cytomegalovirus caused colonic lesions in 35.7% of the cases. Candidiasis was observed in 26.6% mainly in the mouth and herpes simplex (8.8%) was the important agent of esophageal lesions. Oral hairy leukoplasia associated with HPV was found in 16 (35.5%) cases. Neoplasia was diagnosed in 7 (15.5%) cases: four Kaposi's sarcoma, two anal intramucosal carcinomas and one gastric lymphoma. Our data confirm the high frequency and variety of GI tract alterations in AIDS. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-07-01 2014-05-27T11:17:57Z 2014-05-27T11:17:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0037-86821994000300003 Revista da Sociedade Brasileira de Medicina Tropical, v. 27, n. 3, p. 135-141, 1994. 0037-8682 http://hdl.handle.net/11449/64488 10.1590/S0037-86821994000300003 S0037-86821994000300003 2-s2.0-0028474054 2-s2.0-0028474054.pdf |
url |
http://dx.doi.org/10.1590/S0037-86821994000300003 http://hdl.handle.net/11449/64488 |
identifier_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical, v. 27, n. 3, p. 135-141, 1994. 0037-8682 10.1590/S0037-86821994000300003 S0037-86821994000300003 2-s2.0-0028474054 2-s2.0-0028474054.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical 1.358 0,658 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
135-141 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1799965483976359936 |