Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5433/1679-0359.2013v34n4p1807 http://hdl.handle.net/11449/75874 |
Resumo: | Constant rate infusion (CRI) shows several advantages in balanced anesthesia, such as reduction of requirement for inhaled anesthetics and control of pain. The most commonly used drugs in these protocols are local anesthetics, dissociative, and opioids, which may be administered alone or in combinations. We evaluated the records of 200 dogs that underwent various surgical procedures with anesthetic or analgesic CRI in the perioperative period during 2011 and 2012 at the Veterinary Hospital of Franca University (Unifran), and identified possible complications during the transoperative period. Records evaluated included clinical state, laboratory tests, drugs used in premedication and induction, and CRI protocol. Acepromazine and morphine were the main drugs used in premedication. Propofol was used to induce anesthesia alone or in combination with other agents. We evaluated records of the 25 different CRI protocols. Fentanyl was the main drug employed in CRI, either alone or in combination. There were 128 episodes of anesthetic complications during CRI;the most common were hypotension, hypertension, and tachycardia, which occurred in 43 (32%), 35 (26.3%), and 19 (14.2%) dogs, respectively. Cardiac arrhythmia was reported in only 4 dogs. Signs of respiratory depression were present in dogs treated with 6 different CRI protocols. The consumption of isoflurane (vol %) reduced between 15.7% and 21.05% after 30minutes of the CRI in the fentanyl and fentanyl-lidocaine-ketamine CRI groups (p<0.05). In conclusion, CRI is a valid component of balanced anesthesia in dogs, safe, and has a low incidence of adverse effects. However, future studies are warranted to describe the results of the clinical use of CRI to better characterize and refine this technique. |
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Repositório Institucional da UNESP |
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Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogsContinuous intravenous infusionFentanylKetamineLidocaineMorphineConstant rate infusion (CRI) shows several advantages in balanced anesthesia, such as reduction of requirement for inhaled anesthetics and control of pain. The most commonly used drugs in these protocols are local anesthetics, dissociative, and opioids, which may be administered alone or in combinations. We evaluated the records of 200 dogs that underwent various surgical procedures with anesthetic or analgesic CRI in the perioperative period during 2011 and 2012 at the Veterinary Hospital of Franca University (Unifran), and identified possible complications during the transoperative period. Records evaluated included clinical state, laboratory tests, drugs used in premedication and induction, and CRI protocol. Acepromazine and morphine were the main drugs used in premedication. Propofol was used to induce anesthesia alone or in combination with other agents. We evaluated records of the 25 different CRI protocols. Fentanyl was the main drug employed in CRI, either alone or in combination. There were 128 episodes of anesthetic complications during CRI;the most common were hypotension, hypertension, and tachycardia, which occurred in 43 (32%), 35 (26.3%), and 19 (14.2%) dogs, respectively. Cardiac arrhythmia was reported in only 4 dogs. Signs of respiratory depression were present in dogs treated with 6 different CRI protocols. The consumption of isoflurane (vol %) reduced between 15.7% and 21.05% after 30minutes of the CRI in the fentanyl and fentanyl-lidocaine-ketamine CRI groups (p<0.05). In conclusion, CRI is a valid component of balanced anesthesia in dogs, safe, and has a low incidence of adverse effects. However, future studies are warranted to describe the results of the clinical use of CRI to better characterize and refine this technique.Universidade de Franca UNIFRAN, Franca, SPUniversidade Estadual Paulista Júlio de Mesquita Filho Campus Botucatu UNESP, Botucatu, SPUniversidade Estadual de Santa Cruz UESC, Ilhéus, BAUniversidade Estadual Paulista Júlio de Mesquita Filho Campus Botucatu UNESP, Botucatu, SPUNIFRANUniversidade Estadual Paulista (Unesp)Universidade Estadual de Santa Cruz (UESC)De Amorim Cerejo, SofiaDe Mattos Jr., EwaldoNishimura, Lilian ToshikoQuarterone, Carolina [UNESP]Franco, Leandro Guimarães2014-05-27T11:29:54Z2014-05-27T11:29:54Z2013-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1807-1822application/pdfhttp://dx.doi.org/10.5433/1679-0359.2013v34n4p1807Semina:Ciencias Agrarias, v. 34, n. 4, p. 1807-1822, 2013.1676-546X1679-0359http://hdl.handle.net/11449/7587410.5433/1679-0359.2013v34n4p1807WOS:0003282699000332-s2.0-848851175122-s2.0-84885117512.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSemina: Ciências Agrárias0.3490,320info:eu-repo/semantics/openAccess2023-12-07T06:21:35Zoai:repositorio.unesp.br:11449/75874Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:44:34.552497Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
title |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
spellingShingle |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs De Amorim Cerejo, Sofia Continuous intravenous infusion Fentanyl Ketamine Lidocaine Morphine |
title_short |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
title_full |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
title_fullStr |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
title_full_unstemmed |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
title_sort |
Effects of constant rate infusion of anesthetic or analgesic drugs on general anesthesia with isoflurane: A retrospective study in 200 dogs |
author |
De Amorim Cerejo, Sofia |
author_facet |
De Amorim Cerejo, Sofia De Mattos Jr., Ewaldo Nishimura, Lilian Toshiko Quarterone, Carolina [UNESP] Franco, Leandro Guimarães |
author_role |
author |
author2 |
De Mattos Jr., Ewaldo Nishimura, Lilian Toshiko Quarterone, Carolina [UNESP] Franco, Leandro Guimarães |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
UNIFRAN Universidade Estadual Paulista (Unesp) Universidade Estadual de Santa Cruz (UESC) |
dc.contributor.author.fl_str_mv |
De Amorim Cerejo, Sofia De Mattos Jr., Ewaldo Nishimura, Lilian Toshiko Quarterone, Carolina [UNESP] Franco, Leandro Guimarães |
dc.subject.por.fl_str_mv |
Continuous intravenous infusion Fentanyl Ketamine Lidocaine Morphine |
topic |
Continuous intravenous infusion Fentanyl Ketamine Lidocaine Morphine |
description |
Constant rate infusion (CRI) shows several advantages in balanced anesthesia, such as reduction of requirement for inhaled anesthetics and control of pain. The most commonly used drugs in these protocols are local anesthetics, dissociative, and opioids, which may be administered alone or in combinations. We evaluated the records of 200 dogs that underwent various surgical procedures with anesthetic or analgesic CRI in the perioperative period during 2011 and 2012 at the Veterinary Hospital of Franca University (Unifran), and identified possible complications during the transoperative period. Records evaluated included clinical state, laboratory tests, drugs used in premedication and induction, and CRI protocol. Acepromazine and morphine were the main drugs used in premedication. Propofol was used to induce anesthesia alone or in combination with other agents. We evaluated records of the 25 different CRI protocols. Fentanyl was the main drug employed in CRI, either alone or in combination. There were 128 episodes of anesthetic complications during CRI;the most common were hypotension, hypertension, and tachycardia, which occurred in 43 (32%), 35 (26.3%), and 19 (14.2%) dogs, respectively. Cardiac arrhythmia was reported in only 4 dogs. Signs of respiratory depression were present in dogs treated with 6 different CRI protocols. The consumption of isoflurane (vol %) reduced between 15.7% and 21.05% after 30minutes of the CRI in the fentanyl and fentanyl-lidocaine-ketamine CRI groups (p<0.05). In conclusion, CRI is a valid component of balanced anesthesia in dogs, safe, and has a low incidence of adverse effects. However, future studies are warranted to describe the results of the clinical use of CRI to better characterize and refine this technique. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-01 2014-05-27T11:29:54Z 2014-05-27T11:29:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5433/1679-0359.2013v34n4p1807 Semina:Ciencias Agrarias, v. 34, n. 4, p. 1807-1822, 2013. 1676-546X 1679-0359 http://hdl.handle.net/11449/75874 10.5433/1679-0359.2013v34n4p1807 WOS:000328269900033 2-s2.0-84885117512 2-s2.0-84885117512.pdf |
url |
http://dx.doi.org/10.5433/1679-0359.2013v34n4p1807 http://hdl.handle.net/11449/75874 |
identifier_str_mv |
Semina:Ciencias Agrarias, v. 34, n. 4, p. 1807-1822, 2013. 1676-546X 1679-0359 10.5433/1679-0359.2013v34n4p1807 WOS:000328269900033 2-s2.0-84885117512 2-s2.0-84885117512.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Semina: Ciências Agrárias 0.349 0,320 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1807-1822 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129111911038976 |