Oral candidosis by Candida albicans in normal and xerostomic mice

Detalhes bibliográficos
Autor(a) principal: Totti, Marilda Aparecida Gonçalves
Data de Publicação: 2004
Outros Autores: Santos, Elisabete Brasil Dos, Almeida, Oslei Paes De, Koga-ito, Cristiane Yumi [UNESP], Jorge, Antonio Olavo Cardoso
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1806-83242004000300005
http://hdl.handle.net/11449/213127
Resumo: The aim of this study was to analyze the effect of sialoadenectomy on the development of oral candidosis after one or four inoculations of Candida albicans. Initially, a suspension containing 10(8) cells/ml of C. albicans ATCC 36801 was prepared. Seventy-eight sialoadenectomized mice and a similar amount of mice with normal salivary flow received a single inoculation of C. albicans suspension. Another group with a similar number of mice received 4 inoculations. The control group consisted of 6 sialoadenectomized mice and 6 mice with normal salivary flow that were not inoculated with C. albicans. Candidosis development was studied histologically in the tongue of the animals 1, 2, 3, 5, and 8 days after inoculation and at 15-day intervals up to 165 days. According to the results obtained, it could be concluded that sialoadenectomy and a higher frequency of yeast inoculation influenced the presence and extension of candidosis lesions.
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spelling Oral candidosis by Candida albicans in normal and xerostomic miceCandidose oral por Candida albicans em camundongos normais e xerostômicosCandidiasis, oralCandida albicansXerostomiaCandidíase bucalCandida albicansXerostomiaThe aim of this study was to analyze the effect of sialoadenectomy on the development of oral candidosis after one or four inoculations of Candida albicans. Initially, a suspension containing 10(8) cells/ml of C. albicans ATCC 36801 was prepared. Seventy-eight sialoadenectomized mice and a similar amount of mice with normal salivary flow received a single inoculation of C. albicans suspension. Another group with a similar number of mice received 4 inoculations. The control group consisted of 6 sialoadenectomized mice and 6 mice with normal salivary flow that were not inoculated with C. albicans. Candidosis development was studied histologically in the tongue of the animals 1, 2, 3, 5, and 8 days after inoculation and at 15-day intervals up to 165 days. According to the results obtained, it could be concluded that sialoadenectomy and a higher frequency of yeast inoculation influenced the presence and extension of candidosis lesions.O objetivo deste estudo foi analisar o efeito da sialoadenectomia sobre o desenvolvimento da candidose oral após uma ou quatro inoculações de Candida albicans. Inicialmente, uma suspensão contendo 10(8) células/ml de C. albicans ATCC 36801 foi preparada. Setenta e oito camundongos sialoadenectomizados e mesma quantidade de camundongos com fluxo salivar normal receberam uma única inoculação de suspensão de C. albicans. Outro grupo, com o mesmo número de camundongos, recebeu 4 inoculações. O grupo controle consistiu de 6 camundongos sialoadenectomizados e 6 com fluxo salivar normal que não foram inoculados com C. albicans. O desenvolvimento de candidose foi estudado histologicamente na língua dos animais em períodos de 1, 2, 3, 5 e 8 dias após a inoculação e em intervalos de 15 dias até 165 dias. De acordo com os resultados obtidos, conclui-se que a sialoadenectomia e uma maior freqüência de inoculação influenciaram na presença e extensão das lesões de candidose.Universidade Estadual de Campinas, School of Dentistry of PiracicabaUniversity of Ponta Grossa, Department of DentistryUniversidade Estadual Paulista, School of Dentistry of São José dos CamposUniversity of Taubaté, Department of DentistryUniversidade Estadual Paulista, School of Dentistry of São José dos CamposSociedade Brasileira de Pesquisa Odontológica - SBPqOUniversidade Estadual de Campinas (UNICAMP)University of Ponta GrossaUniversidade Estadual Paulista (Unesp)University of TaubatéTotti, Marilda Aparecida GonçalvesSantos, Elisabete Brasil DosAlmeida, Oslei Paes DeKoga-ito, Cristiane Yumi [UNESP]Jorge, Antonio Olavo Cardoso2021-07-14T10:50:28Z2021-07-14T10:50:28Z2004-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article202-207application/pdfhttp://dx.doi.org/10.1590/S1806-83242004000300005Brazilian Oral Research. São Paulo, SP, Brazil: Sociedade Brasileira de Pesquisa Odontológica - SBPqO, v. 18, n. 3, p. 202-207, 2004.1806-83241807-3107http://hdl.handle.net/11449/21312710.1590/S1806-83242004000300005S1806-83242004000300005S1806-83242004000300005.pdf65435631614034210000-0002-2416-2173SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Oral Researchinfo:eu-repo/semantics/openAccess2023-12-19T06:19:26Zoai:repositorio.unesp.br:11449/213127Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:43:49.186649Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Oral candidosis by Candida albicans in normal and xerostomic mice
Candidose oral por Candida albicans em camundongos normais e xerostômicos
title Oral candidosis by Candida albicans in normal and xerostomic mice
spellingShingle Oral candidosis by Candida albicans in normal and xerostomic mice
Totti, Marilda Aparecida Gonçalves
Candidiasis, oral
Candida albicans
Xerostomia
Candidíase bucal
Candida albicans
Xerostomia
title_short Oral candidosis by Candida albicans in normal and xerostomic mice
title_full Oral candidosis by Candida albicans in normal and xerostomic mice
title_fullStr Oral candidosis by Candida albicans in normal and xerostomic mice
title_full_unstemmed Oral candidosis by Candida albicans in normal and xerostomic mice
title_sort Oral candidosis by Candida albicans in normal and xerostomic mice
author Totti, Marilda Aparecida Gonçalves
author_facet Totti, Marilda Aparecida Gonçalves
Santos, Elisabete Brasil Dos
Almeida, Oslei Paes De
Koga-ito, Cristiane Yumi [UNESP]
Jorge, Antonio Olavo Cardoso
author_role author
author2 Santos, Elisabete Brasil Dos
Almeida, Oslei Paes De
Koga-ito, Cristiane Yumi [UNESP]
Jorge, Antonio Olavo Cardoso
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
University of Ponta Grossa
Universidade Estadual Paulista (Unesp)
University of Taubaté
dc.contributor.author.fl_str_mv Totti, Marilda Aparecida Gonçalves
Santos, Elisabete Brasil Dos
Almeida, Oslei Paes De
Koga-ito, Cristiane Yumi [UNESP]
Jorge, Antonio Olavo Cardoso
dc.subject.por.fl_str_mv Candidiasis, oral
Candida albicans
Xerostomia
Candidíase bucal
Candida albicans
Xerostomia
topic Candidiasis, oral
Candida albicans
Xerostomia
Candidíase bucal
Candida albicans
Xerostomia
description The aim of this study was to analyze the effect of sialoadenectomy on the development of oral candidosis after one or four inoculations of Candida albicans. Initially, a suspension containing 10(8) cells/ml of C. albicans ATCC 36801 was prepared. Seventy-eight sialoadenectomized mice and a similar amount of mice with normal salivary flow received a single inoculation of C. albicans suspension. Another group with a similar number of mice received 4 inoculations. The control group consisted of 6 sialoadenectomized mice and 6 mice with normal salivary flow that were not inoculated with C. albicans. Candidosis development was studied histologically in the tongue of the animals 1, 2, 3, 5, and 8 days after inoculation and at 15-day intervals up to 165 days. According to the results obtained, it could be concluded that sialoadenectomy and a higher frequency of yeast inoculation influenced the presence and extension of candidosis lesions.
publishDate 2004
dc.date.none.fl_str_mv 2004-09
2021-07-14T10:50:28Z
2021-07-14T10:50:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1806-83242004000300005
Brazilian Oral Research. São Paulo, SP, Brazil: Sociedade Brasileira de Pesquisa Odontológica - SBPqO, v. 18, n. 3, p. 202-207, 2004.
1806-8324
1807-3107
http://hdl.handle.net/11449/213127
10.1590/S1806-83242004000300005
S1806-83242004000300005
S1806-83242004000300005.pdf
6543563161403421
0000-0002-2416-2173
url http://dx.doi.org/10.1590/S1806-83242004000300005
http://hdl.handle.net/11449/213127
identifier_str_mv Brazilian Oral Research. São Paulo, SP, Brazil: Sociedade Brasileira de Pesquisa Odontológica - SBPqO, v. 18, n. 3, p. 202-207, 2004.
1806-8324
1807-3107
10.1590/S1806-83242004000300005
S1806-83242004000300005
S1806-83242004000300005.pdf
6543563161403421
0000-0002-2416-2173
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Oral Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 202-207
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129239301488640

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