Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Ana Rosa [UNESP]
Data de Publicação: 2017
Outros Autores: Gemini-Piperni, Sara, Alves, Sofia Afonso, Granjeiro, José Mauro, Rocha, Luís Augusto [UNESP]
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/978-3-319-63790-7_6
http://hdl.handle.net/11449/221029
Resumo: Titanium dioxide nanotubes and nanoparticles are believed to be stable, possess antibacterial properties, and biocompatible and less toxic than other nanostructures, making them excellent candidates for biomedical applications. Among others, they have been widely used as drug-delivery systems, components for articulating orthopaedic implants or cosmetics for dermatological and skin lesion treatments. However, when exposed to the biological environment, selective proteins and ions may adsorb to the nanostructures creating a dynamic nano-bio interface that mediate a cellular response. This complex nano-bio interface depends on the physical-chemical characteristics of the nanostructures as well as the specific biological environment. In this chapter, the formation of these biocomplexes (protein and ions) is discussed together with its impact on cellular behaviour. Finally, the potential application of TiO2 nanoparticles and nanotubes in nanomedicine will be addressed.
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spelling Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicineNano-bio interfaceNanomedicineNanoparticlesNanotechnologyNanotoxicologyNanotubesRegulationTitanium dioxideTitanium dioxide nanotubes and nanoparticles are believed to be stable, possess antibacterial properties, and biocompatible and less toxic than other nanostructures, making them excellent candidates for biomedical applications. Among others, they have been widely used as drug-delivery systems, components for articulating orthopaedic implants or cosmetics for dermatological and skin lesion treatments. However, when exposed to the biological environment, selective proteins and ions may adsorb to the nanostructures creating a dynamic nano-bio interface that mediate a cellular response. This complex nano-bio interface depends on the physical-chemical characteristics of the nanostructures as well as the specific biological environment. In this chapter, the formation of these biocomplexes (protein and ions) is discussed together with its impact on cellular behaviour. Finally, the potential application of TiO2 nanoparticles and nanotubes in nanomedicine will be addressed.Directory of Life Sciences Applied Metrology National Institute of Metrology Quality and TechnologyPhysics Department University Estadual PaulistaPostgraduate Program in Clinical and Experimental Dentistry (Odontoclinex) University of Grande RioBiomaterials Laboratory Applied Physics Department Brazilian Center for Physics Research-CBPF, Rua Dr. Xavier da Sigaud 150Brazilian Branch Institute of Biomaterials Tribocorrosion and Nanomedicine (IBTN)Center for MicroElectroMechanical Systems Universidade do MinhoDental School Fluminense Federal UniversityPhysics Department University Estadual PaulistaQuality and TechnologyUniversidade Estadual Paulista (UNESP)University of Grande RioBrazilian Center for Physics Research-CBPFTribocorrosion and Nanomedicine (IBTN)Universidade do MinhoFluminense Federal UniversityRibeiro, Ana Rosa [UNESP]Gemini-Piperni, SaraAlves, Sofia AfonsoGranjeiro, José MauroRocha, Luís Augusto [UNESP]2022-04-28T19:08:45Z2022-04-28T19:08:45Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart101-121http://dx.doi.org/10.1007/978-3-319-63790-7_6Metal Nanoparticles in Pharma, p. 101-121.http://hdl.handle.net/11449/22102910.1007/978-3-319-63790-7_62-s2.0-85042681960Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMetal Nanoparticles in Pharmainfo:eu-repo/semantics/openAccess2022-04-28T19:08:45Zoai:repositorio.unesp.br:11449/221029Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:14:15.322476Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
title Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
spellingShingle Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
Ribeiro, Ana Rosa [UNESP]
Nano-bio interface
Nanomedicine
Nanoparticles
Nanotechnology
Nanotoxicology
Nanotubes
Regulation
Titanium dioxide
title_short Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
title_full Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
title_fullStr Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
title_full_unstemmed Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
title_sort Titanium dioxide nanoparticles and nanotubular surfaces: Potential applications in nanomedicine
author Ribeiro, Ana Rosa [UNESP]
author_facet Ribeiro, Ana Rosa [UNESP]
Gemini-Piperni, Sara
Alves, Sofia Afonso
Granjeiro, José Mauro
Rocha, Luís Augusto [UNESP]
author_role author
author2 Gemini-Piperni, Sara
Alves, Sofia Afonso
Granjeiro, José Mauro
Rocha, Luís Augusto [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Quality and Technology
Universidade Estadual Paulista (UNESP)
University of Grande Rio
Brazilian Center for Physics Research-CBPF
Tribocorrosion and Nanomedicine (IBTN)
Universidade do Minho
Fluminense Federal University
dc.contributor.author.fl_str_mv Ribeiro, Ana Rosa [UNESP]
Gemini-Piperni, Sara
Alves, Sofia Afonso
Granjeiro, José Mauro
Rocha, Luís Augusto [UNESP]
dc.subject.por.fl_str_mv Nano-bio interface
Nanomedicine
Nanoparticles
Nanotechnology
Nanotoxicology
Nanotubes
Regulation
Titanium dioxide
topic Nano-bio interface
Nanomedicine
Nanoparticles
Nanotechnology
Nanotoxicology
Nanotubes
Regulation
Titanium dioxide
description Titanium dioxide nanotubes and nanoparticles are believed to be stable, possess antibacterial properties, and biocompatible and less toxic than other nanostructures, making them excellent candidates for biomedical applications. Among others, they have been widely used as drug-delivery systems, components for articulating orthopaedic implants or cosmetics for dermatological and skin lesion treatments. However, when exposed to the biological environment, selective proteins and ions may adsorb to the nanostructures creating a dynamic nano-bio interface that mediate a cellular response. This complex nano-bio interface depends on the physical-chemical characteristics of the nanostructures as well as the specific biological environment. In this chapter, the formation of these biocomplexes (protein and ions) is discussed together with its impact on cellular behaviour. Finally, the potential application of TiO2 nanoparticles and nanotubes in nanomedicine will be addressed.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
2022-04-28T19:08:45Z
2022-04-28T19:08:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/978-3-319-63790-7_6
Metal Nanoparticles in Pharma, p. 101-121.
http://hdl.handle.net/11449/221029
10.1007/978-3-319-63790-7_6
2-s2.0-85042681960
url http://dx.doi.org/10.1007/978-3-319-63790-7_6
http://hdl.handle.net/11449/221029
identifier_str_mv Metal Nanoparticles in Pharma, p. 101-121.
10.1007/978-3-319-63790-7_6
2-s2.0-85042681960
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Metal Nanoparticles in Pharma
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 101-121
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129501123575808

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