Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/208715 |
Resumo: | Sena KF, Pursunh DC, Zanesco A, Rodrigues TR, Martins CCL, Cavalcanti-Dantas VM, Cardoso GA, Nascimento EDS, Ribeiro MD, Silva AS. Influence of Ethnicity and Gene Polymorphism T- 786C eNOS on Post-Exercise Hypotension in Hypertensive Adults. JEPonline 2020; 23(2):61-70. The purpose of this study was to verify the influence of ethnicity and polymorphism on the eNOS T-786C gene (rs2070744) in the response of blood pressure to an exercise session. Eighty-nine hypertensive subjects (age, 57.6 ± 8.7 yrs; 26 with white skin and 63 with dark skin) were initially genotyped and submitted to a 60-min running/walking session of moderate intensity. Their blood pressure was measured before exercise, immediately after exercise, and every 10 min of a 60-min recovery period after exercise. There was a decrease in post-exercise systolic blood pressure of 6.9 ± 11.0 mmHg at 10 min, which increased to 10.9 ± 12.0 mmHg at 20 min. Then, it remained stable for the rest of the recovery period. Ethnicity and genotype did not modify these responses. The results indicate that hypertensive subjects with dark skin also benefit by the phenomenon of post-exercise hypotension. |
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Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive AdultsAerobic ExerciseEthnic GroupsGenetic PolymorphismPost-Exercise HypotensionSena KF, Pursunh DC, Zanesco A, Rodrigues TR, Martins CCL, Cavalcanti-Dantas VM, Cardoso GA, Nascimento EDS, Ribeiro MD, Silva AS. Influence of Ethnicity and Gene Polymorphism T- 786C eNOS on Post-Exercise Hypotension in Hypertensive Adults. JEPonline 2020; 23(2):61-70. The purpose of this study was to verify the influence of ethnicity and polymorphism on the eNOS T-786C gene (rs2070744) in the response of blood pressure to an exercise session. Eighty-nine hypertensive subjects (age, 57.6 ± 8.7 yrs; 26 with white skin and 63 with dark skin) were initially genotyped and submitted to a 60-min running/walking session of moderate intensity. Their blood pressure was measured before exercise, immediately after exercise, and every 10 min of a 60-min recovery period after exercise. There was a decrease in post-exercise systolic blood pressure of 6.9 ± 11.0 mmHg at 10 min, which increased to 10.9 ± 12.0 mmHg at 20 min. Then, it remained stable for the rest of the recovery period. Ethnicity and genotype did not modify these responses. The results indicate that hypertensive subjects with dark skin also benefit by the phenomenon of post-exercise hypotension.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Department of Physical Education Federal University of ParaíbaDepartment of Molecular Biology Federal University of ParaíbaLaboratory of Cardiovascular Physiology and Exercise Science Institute of Biosciences UNESPLaboratory of Cardiovascular Physiology and Exercise Science Institute of Biosciences UNESPFederal University of ParaíbaUniversidade Estadual Paulista (Unesp)Sena, KleciaPursunh, DarleneZanesco, Angelina [UNESP]Rodrigues, ThaisMartins, CamilaCavalcanti-Dantas, VanessaCardoso, GlêbiaNascimento, ElijacksonRibeiro, MateusSilva, Alexandre2021-06-25T11:17:48Z2021-06-25T11:17:48Z2020-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article61-70Journal of Exercise Physiology Online, v. 23, n. 2, p. 61-70, 2020.1097-9751http://hdl.handle.net/11449/2087152-s2.0-85106574310Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Exercise Physiology Onlineinfo:eu-repo/semantics/openAccess2021-10-23T19:02:26Zoai:repositorio.unesp.br:11449/208715Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:35:02.821425Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
title |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
spellingShingle |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults Sena, Klecia Aerobic Exercise Ethnic Groups Genetic Polymorphism Post-Exercise Hypotension |
title_short |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
title_full |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
title_fullStr |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
title_full_unstemmed |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
title_sort |
Influence of Ethnicity and Gene Polymorphism T-786C eNOS on Post-Exercise Hypotension in Hypertensive Adults |
author |
Sena, Klecia |
author_facet |
Sena, Klecia Pursunh, Darlene Zanesco, Angelina [UNESP] Rodrigues, Thais Martins, Camila Cavalcanti-Dantas, Vanessa Cardoso, Glêbia Nascimento, Elijackson Ribeiro, Mateus Silva, Alexandre |
author_role |
author |
author2 |
Pursunh, Darlene Zanesco, Angelina [UNESP] Rodrigues, Thais Martins, Camila Cavalcanti-Dantas, Vanessa Cardoso, Glêbia Nascimento, Elijackson Ribeiro, Mateus Silva, Alexandre |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Federal University of Paraíba Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Sena, Klecia Pursunh, Darlene Zanesco, Angelina [UNESP] Rodrigues, Thais Martins, Camila Cavalcanti-Dantas, Vanessa Cardoso, Glêbia Nascimento, Elijackson Ribeiro, Mateus Silva, Alexandre |
dc.subject.por.fl_str_mv |
Aerobic Exercise Ethnic Groups Genetic Polymorphism Post-Exercise Hypotension |
topic |
Aerobic Exercise Ethnic Groups Genetic Polymorphism Post-Exercise Hypotension |
description |
Sena KF, Pursunh DC, Zanesco A, Rodrigues TR, Martins CCL, Cavalcanti-Dantas VM, Cardoso GA, Nascimento EDS, Ribeiro MD, Silva AS. Influence of Ethnicity and Gene Polymorphism T- 786C eNOS on Post-Exercise Hypotension in Hypertensive Adults. JEPonline 2020; 23(2):61-70. The purpose of this study was to verify the influence of ethnicity and polymorphism on the eNOS T-786C gene (rs2070744) in the response of blood pressure to an exercise session. Eighty-nine hypertensive subjects (age, 57.6 ± 8.7 yrs; 26 with white skin and 63 with dark skin) were initially genotyped and submitted to a 60-min running/walking session of moderate intensity. Their blood pressure was measured before exercise, immediately after exercise, and every 10 min of a 60-min recovery period after exercise. There was a decrease in post-exercise systolic blood pressure of 6.9 ± 11.0 mmHg at 10 min, which increased to 10.9 ± 12.0 mmHg at 20 min. Then, it remained stable for the rest of the recovery period. Ethnicity and genotype did not modify these responses. The results indicate that hypertensive subjects with dark skin also benefit by the phenomenon of post-exercise hypotension. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-01 2021-06-25T11:17:48Z 2021-06-25T11:17:48Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Journal of Exercise Physiology Online, v. 23, n. 2, p. 61-70, 2020. 1097-9751 http://hdl.handle.net/11449/208715 2-s2.0-85106574310 |
identifier_str_mv |
Journal of Exercise Physiology Online, v. 23, n. 2, p. 61-70, 2020. 1097-9751 2-s2.0-85106574310 |
url |
http://hdl.handle.net/11449/208715 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Exercise Physiology Online |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
61-70 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129223157612544 |