Protocolo para ensaios físico-químicos de estabilidade de fitocosméticos

• Autor(a) principal: Isaac, Vera Lucia Borges [UNESP]
• Data de Publicação: 2008
• Outros Autores: Cefali, L. C. [UNESP], Chiari, B. G. [UNESP], Oliveira, C. C L G [UNESP], Salgado, Hérida Regina Nunes [UNESP], Correa, Marcos Antonio [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/438; http://hdl.handle.net/11449/70617
• topic: Brazilian biodiversity; Physical and chemical stability; Phytocosmetic; cosmetic; biodiversity; Brazil; calorimetry; fluorometry; physical chemistry; quality control; thermal analysis

The growing demand for stable, safe and effective cosmetics has required increasingly complex studies by the scientific community and the use of more efficient techniques to determine the stability of these products. The use of active principles from the Brazilian flora has led to the development of numerous products, in the most varied pharmaceutical forms, making it, even more difficult to standardize experimental protocols to certify the stability of cosmetic preparations. While in Brazil there is no one protocol that standardizes the tests that should be carried out to determine product stability, several studies have been conducted in academic laboratories to determine the stability of specific raw materials. The rheological properties of topical use products have to be taken into account in their manufacture, storage and application. The determination of the rheological behavior of a formulation helps in evaluating the physicochemical nature of the vehicle, allowing early signs of physical instability to be detected and thus enabling quality control of the constituents, test formulations and final products. Thermal analysis has also been used to assist in the study of cosmetic stability and differential scanning calorimetry to guide the development of new products. Other tools, such as fluorimetry and laser granulometry can be used to help the study and development of both emulsified and non-emulsified systems. The aim of the present study is to develop a protocol for the investigation of the physical and chemical stability of phytocosmetics - systems containing active compounds extracted from the Brazilian biodiversity.