EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA
Autor(a) principal: | |
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Data de Publicação: | 1992 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://ecb.thulb.uni-jena.de/receive/jportal_jparticle_00059861 http://hdl.handle.net/11449/32187 |
Resumo: | The frequency of adenine mononucleotides (A), dinucleotides (AA) and clusters, and the positions of clusters, were studied in 502 molecules of the 5S rRNA.All frequencies were reduced in the evolutive lines of vertebrates, plants and fungi, in parallel with increasing organismic complexity. No change was observed in invertebrates. All frequencies were increased in mitochondria, plastids and mycoplasmas. The presumed relatives to the ancestors of the organelles, Rhodobacteria alfa and Cyanobacteria, showed intermediate values, relative to the eubacterial averages. Firmibacterid showed very high number of cluster sites.Clusters were more frequent in single-stranded regions in all organisms. The routes of organelles and mycoplasmas accummulated clusters at faster rates in double-stranded regions. Rates of change were higher for AA and clusters than for A in plants, vertebrates and organeltes, higher for cluster sites and A in mycoplasmas, and higher for AA and A in fungi. These data indicated that selection pressures acted more strongly on adenine clustering than on adenine frequency.It is proposed that AA and clusters, as sites of lower informational content. have the property of tolerating positional variation in the sites of other molecules (or other regions of the same molecule) that interact with the adenines. This reasoning was consistent with the degrees of genic polymorphism. low in plants and vertebrates and high in invertebrates. In the eubacteria endosymbiontic or parasitic to eukaryotes, the more tolerant RNA would be better adapted to interactions with the homologous nucleus-derived ribosomal proteins: the intermediate values observed in their precursors were interpreted as preadaptive.Among other groups, only the Deinococcus-Thermus eubacteria showed excessive AA and cluster contents, possibly related to their peculiar tolerance to mutagens, and the Ciliates showed excessive AA contents, indicative of retention of primitive characters. |
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Repositório Institucional da UNESP |
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EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA5S RIBOSOMAL-RNAEVOLUTIONADENINE CLUSTERSENDOSYMBIOSISPARASITISMPREADAPTATIONCONVERGENCESIMPLIFICATIONCOMPLEXITYThe frequency of adenine mononucleotides (A), dinucleotides (AA) and clusters, and the positions of clusters, were studied in 502 molecules of the 5S rRNA.All frequencies were reduced in the evolutive lines of vertebrates, plants and fungi, in parallel with increasing organismic complexity. No change was observed in invertebrates. All frequencies were increased in mitochondria, plastids and mycoplasmas. The presumed relatives to the ancestors of the organelles, Rhodobacteria alfa and Cyanobacteria, showed intermediate values, relative to the eubacterial averages. Firmibacterid showed very high number of cluster sites.Clusters were more frequent in single-stranded regions in all organisms. The routes of organelles and mycoplasmas accummulated clusters at faster rates in double-stranded regions. Rates of change were higher for AA and clusters than for A in plants, vertebrates and organeltes, higher for cluster sites and A in mycoplasmas, and higher for AA and A in fungi. These data indicated that selection pressures acted more strongly on adenine clustering than on adenine frequency.It is proposed that AA and clusters, as sites of lower informational content. have the property of tolerating positional variation in the sites of other molecules (or other regions of the same molecule) that interact with the adenines. This reasoning was consistent with the degrees of genic polymorphism. low in plants and vertebrates and high in invertebrates. In the eubacteria endosymbiontic or parasitic to eukaryotes, the more tolerant RNA would be better adapted to interactions with the homologous nucleus-derived ribosomal proteins: the intermediate values observed in their precursors were interpreted as preadaptive.Among other groups, only the Deinococcus-Thermus eubacteria showed excessive AA and cluster contents, possibly related to their peculiar tolerance to mutagens, and the Ciliates showed excessive AA contents, indicative of retention of primitive characters.FREE UNIV BERLIN,FACHBEREICH CHEM,INST BIOCHEM,W-1000 BERLIN 33,GERMANYTubingen Univ Press Attempto VerlagFREE UNIV BERLINUniversidade Estadual Paulista (Unesp)Guimaraes, R. C.Erdmann, V. A.2014-05-20T15:21:00Z2014-05-20T15:21:00Z1992-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13-45http://ecb.thulb.uni-jena.de/receive/jportal_jparticle_00059861Endocytobiosis and Cell Research. Tubingen: Tubingen Univ Press Attempto Verlag, v. 9, n. 1, p. 13-45, 1992.0256-1514http://hdl.handle.net/11449/32187WOS:A1992KN26200002Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengEndocytobiosis and Cell Researchinfo:eu-repo/semantics/openAccess2021-10-22T19:58:03Zoai:repositorio.unesp.br:11449/32187Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T19:58:03Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
title |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
spellingShingle |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA Guimaraes, R. C. 5S RIBOSOMAL-RNA EVOLUTION ADENINE CLUSTERS ENDOSYMBIOSIS PARASITISM PREADAPTATION CONVERGENCE SIMPLIFICATION COMPLEXITY |
title_short |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
title_full |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
title_fullStr |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
title_full_unstemmed |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
title_sort |
EVOLUTION OF ADENINE CLUSTERING IN 5S RIBOSOMAL-RNA |
author |
Guimaraes, R. C. |
author_facet |
Guimaraes, R. C. Erdmann, V. A. |
author_role |
author |
author2 |
Erdmann, V. A. |
author2_role |
author |
dc.contributor.none.fl_str_mv |
FREE UNIV BERLIN Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Guimaraes, R. C. Erdmann, V. A. |
dc.subject.por.fl_str_mv |
5S RIBOSOMAL-RNA EVOLUTION ADENINE CLUSTERS ENDOSYMBIOSIS PARASITISM PREADAPTATION CONVERGENCE SIMPLIFICATION COMPLEXITY |
topic |
5S RIBOSOMAL-RNA EVOLUTION ADENINE CLUSTERS ENDOSYMBIOSIS PARASITISM PREADAPTATION CONVERGENCE SIMPLIFICATION COMPLEXITY |
description |
The frequency of adenine mononucleotides (A), dinucleotides (AA) and clusters, and the positions of clusters, were studied in 502 molecules of the 5S rRNA.All frequencies were reduced in the evolutive lines of vertebrates, plants and fungi, in parallel with increasing organismic complexity. No change was observed in invertebrates. All frequencies were increased in mitochondria, plastids and mycoplasmas. The presumed relatives to the ancestors of the organelles, Rhodobacteria alfa and Cyanobacteria, showed intermediate values, relative to the eubacterial averages. Firmibacterid showed very high number of cluster sites.Clusters were more frequent in single-stranded regions in all organisms. The routes of organelles and mycoplasmas accummulated clusters at faster rates in double-stranded regions. Rates of change were higher for AA and clusters than for A in plants, vertebrates and organeltes, higher for cluster sites and A in mycoplasmas, and higher for AA and A in fungi. These data indicated that selection pressures acted more strongly on adenine clustering than on adenine frequency.It is proposed that AA and clusters, as sites of lower informational content. have the property of tolerating positional variation in the sites of other molecules (or other regions of the same molecule) that interact with the adenines. This reasoning was consistent with the degrees of genic polymorphism. low in plants and vertebrates and high in invertebrates. In the eubacteria endosymbiontic or parasitic to eukaryotes, the more tolerant RNA would be better adapted to interactions with the homologous nucleus-derived ribosomal proteins: the intermediate values observed in their precursors were interpreted as preadaptive.Among other groups, only the Deinococcus-Thermus eubacteria showed excessive AA and cluster contents, possibly related to their peculiar tolerance to mutagens, and the Ciliates showed excessive AA contents, indicative of retention of primitive characters. |
publishDate |
1992 |
dc.date.none.fl_str_mv |
1992-12-01 2014-05-20T15:21:00Z 2014-05-20T15:21:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://ecb.thulb.uni-jena.de/receive/jportal_jparticle_00059861 Endocytobiosis and Cell Research. Tubingen: Tubingen Univ Press Attempto Verlag, v. 9, n. 1, p. 13-45, 1992. 0256-1514 http://hdl.handle.net/11449/32187 WOS:A1992KN26200002 |
url |
http://ecb.thulb.uni-jena.de/receive/jportal_jparticle_00059861 http://hdl.handle.net/11449/32187 |
identifier_str_mv |
Endocytobiosis and Cell Research. Tubingen: Tubingen Univ Press Attempto Verlag, v. 9, n. 1, p. 13-45, 1992. 0256-1514 WOS:A1992KN26200002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Endocytobiosis and Cell Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
13-45 |
dc.publisher.none.fl_str_mv |
Tubingen Univ Press Attempto Verlag |
publisher.none.fl_str_mv |
Tubingen Univ Press Attempto Verlag |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1803045917264183296 |