Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5005/jcdp-8-6-43 http://hdl.handle.net/11449/219420 |
Resumo: | Aim: The aim of this article is to present a case of idiopathic thrombocytopenic purpura (ITP) in order to emphasize the importance of the clinical exam since the anamnesis leads to a diagnostic hypothesis of ITP. Background: Acute ITP is considered an autoimmune disease characterized by the production of antibodies against platelets, antigens produced by a viral infection, or a platelet sparing drug combination. These antibodies adhere to platelets and are recognized and destroyed by the reticulo-endothelial system. Consequently, the platelet count gradually diminishes and is insufficient for the maintenance of primary hemostasis. Report: A 77-year-old woman presented with post-extraction intermittent bleeding. The physical examination revealed discoloration of the skin, multiple petechiae, hematomas, ecchymosis of the upper lip, bruises all over the body, gingiva that bled spontaneously, and a malformed blood clot at the extraction site of tooth #44. The hematological exams confirmed the hypothesis of ITP. The patient was immediately hospitalized in the Hematology Department of a local hospital and received platelet replacement, hydration, medication, and general care. After the spontaneous bleeding stopped, the malformed clot was removed using alveolar curettage along with a thorough cleaning of the extraction site with a 0.9% saline solution before suturing the wound and prescribing medication. After the sixth day of hospitalization, the patient presented with the following results: Hb: 12.3 mg/dL, Ht: 36.1%, and PC: 87,000 mm3. The patient was then discharged and was placed under outpatient follow-up care. Summary: The importance of the clinical exam must be emphasized since the anamnesis leads to a diagnostic hypothesis of ITP and provides the dental surgeon with an opportunity to make important systemic alterations to improve the prognosis of a patient with ITP. |
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Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhageDental surgeryIdiopathic thrombocytopenic purpuraITPPost-extraction hemorrhageSystemic alterationsAim: The aim of this article is to present a case of idiopathic thrombocytopenic purpura (ITP) in order to emphasize the importance of the clinical exam since the anamnesis leads to a diagnostic hypothesis of ITP. Background: Acute ITP is considered an autoimmune disease characterized by the production of antibodies against platelets, antigens produced by a viral infection, or a platelet sparing drug combination. These antibodies adhere to platelets and are recognized and destroyed by the reticulo-endothelial system. Consequently, the platelet count gradually diminishes and is insufficient for the maintenance of primary hemostasis. Report: A 77-year-old woman presented with post-extraction intermittent bleeding. The physical examination revealed discoloration of the skin, multiple petechiae, hematomas, ecchymosis of the upper lip, bruises all over the body, gingiva that bled spontaneously, and a malformed blood clot at the extraction site of tooth #44. The hematological exams confirmed the hypothesis of ITP. The patient was immediately hospitalized in the Hematology Department of a local hospital and received platelet replacement, hydration, medication, and general care. After the spontaneous bleeding stopped, the malformed clot was removed using alveolar curettage along with a thorough cleaning of the extraction site with a 0.9% saline solution before suturing the wound and prescribing medication. After the sixth day of hospitalization, the patient presented with the following results: Hb: 12.3 mg/dL, Ht: 36.1%, and PC: 87,000 mm3. The patient was then discharged and was placed under outpatient follow-up care. Summary: The importance of the clinical exam must be emphasized since the anamnesis leads to a diagnostic hypothesis of ITP and provides the dental surgeon with an opportunity to make important systemic alterations to improve the prognosis of a patient with ITP.Department of Oral Diagnosis School of Dentistry São Paulo State University (FOUSP), São PauloDepartment of Oral and Maxillofacial Surgery Hospital Municipal do Tatuapé (HMCC), São PauloDepartment of Oral and Maxillofacial Surgery Hospital Municipal do Tatuapé (HMCC)Health Sciencies Post-graduation Program Hospital Hellópolis (HOSPHEL), São PauloStomatology Division Department of Oral and Maxillofacial Surgery Hospital Municipal do Tatuapé (HMCC), São PauloDepartment of Oral Diagnosis School of Dentistry São Paulo State University (FOUSP), São PauloUniversidade Estadual Paulista (UNESP)Hospital Municipal do Tatuapé (HMCC)Hospital Hellópolis (HOSPHEL)Martini, Marcelo Zillo [UNESP]Lopez Jr., Jesús SaavedraGendler, Jesé Luiz Pinto LimaDa Fonseca, Eduardo VasquezSoares, Haroldo AridFranzi, Sergio Altini2022-04-28T18:55:34Z2022-04-28T18:55:34Z2007-01-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article43-49http://dx.doi.org/10.5005/jcdp-8-6-43Journal of Contemporary Dental Practice, v. 8, n. 6, p. 43-49, 2007.1526-3711http://hdl.handle.net/11449/21942010.5005/jcdp-8-6-432-s2.0-34548412583Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Contemporary Dental Practiceinfo:eu-repo/semantics/openAccess2022-04-28T18:55:34Zoai:repositorio.unesp.br:11449/219420Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:56:11.712820Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
title |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
spellingShingle |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage Martini, Marcelo Zillo [UNESP] Dental surgery Idiopathic thrombocytopenic purpura ITP Post-extraction hemorrhage Systemic alterations |
title_short |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
title_full |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
title_fullStr |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
title_full_unstemmed |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
title_sort |
Idiopathic thrombocytopenic purpura presenting as post-extraction hemorrhage |
author |
Martini, Marcelo Zillo [UNESP] |
author_facet |
Martini, Marcelo Zillo [UNESP] Lopez Jr., Jesús Saavedra Gendler, Jesé Luiz Pinto Lima Da Fonseca, Eduardo Vasquez Soares, Haroldo Arid Franzi, Sergio Altini |
author_role |
author |
author2 |
Lopez Jr., Jesús Saavedra Gendler, Jesé Luiz Pinto Lima Da Fonseca, Eduardo Vasquez Soares, Haroldo Arid Franzi, Sergio Altini |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Hospital Municipal do Tatuapé (HMCC) Hospital Hellópolis (HOSPHEL) |
dc.contributor.author.fl_str_mv |
Martini, Marcelo Zillo [UNESP] Lopez Jr., Jesús Saavedra Gendler, Jesé Luiz Pinto Lima Da Fonseca, Eduardo Vasquez Soares, Haroldo Arid Franzi, Sergio Altini |
dc.subject.por.fl_str_mv |
Dental surgery Idiopathic thrombocytopenic purpura ITP Post-extraction hemorrhage Systemic alterations |
topic |
Dental surgery Idiopathic thrombocytopenic purpura ITP Post-extraction hemorrhage Systemic alterations |
description |
Aim: The aim of this article is to present a case of idiopathic thrombocytopenic purpura (ITP) in order to emphasize the importance of the clinical exam since the anamnesis leads to a diagnostic hypothesis of ITP. Background: Acute ITP is considered an autoimmune disease characterized by the production of antibodies against platelets, antigens produced by a viral infection, or a platelet sparing drug combination. These antibodies adhere to platelets and are recognized and destroyed by the reticulo-endothelial system. Consequently, the platelet count gradually diminishes and is insufficient for the maintenance of primary hemostasis. Report: A 77-year-old woman presented with post-extraction intermittent bleeding. The physical examination revealed discoloration of the skin, multiple petechiae, hematomas, ecchymosis of the upper lip, bruises all over the body, gingiva that bled spontaneously, and a malformed blood clot at the extraction site of tooth #44. The hematological exams confirmed the hypothesis of ITP. The patient was immediately hospitalized in the Hematology Department of a local hospital and received platelet replacement, hydration, medication, and general care. After the spontaneous bleeding stopped, the malformed clot was removed using alveolar curettage along with a thorough cleaning of the extraction site with a 0.9% saline solution before suturing the wound and prescribing medication. After the sixth day of hospitalization, the patient presented with the following results: Hb: 12.3 mg/dL, Ht: 36.1%, and PC: 87,000 mm3. The patient was then discharged and was placed under outpatient follow-up care. Summary: The importance of the clinical exam must be emphasized since the anamnesis leads to a diagnostic hypothesis of ITP and provides the dental surgeon with an opportunity to make important systemic alterations to improve the prognosis of a patient with ITP. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-01-09 2022-04-28T18:55:34Z 2022-04-28T18:55:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5005/jcdp-8-6-43 Journal of Contemporary Dental Practice, v. 8, n. 6, p. 43-49, 2007. 1526-3711 http://hdl.handle.net/11449/219420 10.5005/jcdp-8-6-43 2-s2.0-34548412583 |
url |
http://dx.doi.org/10.5005/jcdp-8-6-43 http://hdl.handle.net/11449/219420 |
identifier_str_mv |
Journal of Contemporary Dental Practice, v. 8, n. 6, p. 43-49, 2007. 1526-3711 10.5005/jcdp-8-6-43 2-s2.0-34548412583 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Contemporary Dental Practice |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
43-49 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129264560635904 |