Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1155/2018/4218270 http://hdl.handle.net/11449/187410 |
Resumo: | In this study, the preparation of porous nanocomposite scaffolds (HX-CNT) from a combination of a hydroxamic derivative of alginate (HX) and an amine-functionalized multiwalled carbon nanotube (CNT) at different concentrations is described. The structure of HX was investigated by FTIR, and the degree of substitution around 9% was confirmed by elemental analysis. The interaction between CNT and alginate derivative in the nanocomposite crosslinked with calcium was confirmed by FTIR, Raman spectroscopy, and SEM. The results obtained in this study showed that scaffolds based on HX-CNT composites with a 4 wt% concentration level exhibited improved physical and mechanical properties compared to plain alginate (Young's modulus increased from 2.2 to 5.1 MPa and elastic strength from 0.13 to 0.25 MPa) and decreased the swelling ratios from ~900 to ~673. The cytotoxicity assays using the L929 cell line proved that the nanocomposite scaffolds were nontoxic, even at the highest CNT concentration. |
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Repositório Institucional da UNESP |
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Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffoldsIn this study, the preparation of porous nanocomposite scaffolds (HX-CNT) from a combination of a hydroxamic derivative of alginate (HX) and an amine-functionalized multiwalled carbon nanotube (CNT) at different concentrations is described. The structure of HX was investigated by FTIR, and the degree of substitution around 9% was confirmed by elemental analysis. The interaction between CNT and alginate derivative in the nanocomposite crosslinked with calcium was confirmed by FTIR, Raman spectroscopy, and SEM. The results obtained in this study showed that scaffolds based on HX-CNT composites with a 4 wt% concentration level exhibited improved physical and mechanical properties compared to plain alginate (Young's modulus increased from 2.2 to 5.1 MPa and elastic strength from 0.13 to 0.25 MPa) and decreased the swelling ratios from ~900 to ~673. The cytotoxicity assays using the L929 cell line proved that the nanocomposite scaffolds were nontoxic, even at the highest CNT concentration.Departamento de Química e Ciências Ambientais São Paulo State University (UNESP)National Nanotechnology Laboratory for Agriculture (LNNA) Embrapa InstrumentaçãoSão Carlos Institute of Physics University of São Paulo, P. O. Box 369Departamento de Química e Ciências Ambientais São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Universidade de São Paulo (USP)Furuyama Lima, Aline Margarete [UNESP]De Freitas Lima, Marcelo [UNESP]Garrido Assis, Odílio BeneditoRaabe, AliceAmoroso, Hemelen Caroline [UNESP]De Oliveira Tiera, Vera Aparecida [UNESP]De Andrade, Marcelo BarbosaJosé Tiera, Marcio [UNESP]2019-10-06T15:35:20Z2019-10-06T15:35:20Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1155/2018/4218270Journal of Nanomaterials, v. 2018.1687-41291687-4110http://hdl.handle.net/11449/18741010.1155/2018/42182702-s2.0-85062265031Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Nanomaterialsinfo:eu-repo/semantics/openAccess2021-10-23T19:23:36Zoai:repositorio.unesp.br:11449/187410Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:30:13.009334Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
title |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
spellingShingle |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds Furuyama Lima, Aline Margarete [UNESP] |
title_short |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
title_full |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
title_fullStr |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
title_full_unstemmed |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
title_sort |
Synthesis and physicochemical characterization of multiwalled carbon nanotubes/hydroxamic alginate nanocomposite scaffolds |
author |
Furuyama Lima, Aline Margarete [UNESP] |
author_facet |
Furuyama Lima, Aline Margarete [UNESP] De Freitas Lima, Marcelo [UNESP] Garrido Assis, Odílio Benedito Raabe, Alice Amoroso, Hemelen Caroline [UNESP] De Oliveira Tiera, Vera Aparecida [UNESP] De Andrade, Marcelo Barbosa José Tiera, Marcio [UNESP] |
author_role |
author |
author2 |
De Freitas Lima, Marcelo [UNESP] Garrido Assis, Odílio Benedito Raabe, Alice Amoroso, Hemelen Caroline [UNESP] De Oliveira Tiera, Vera Aparecida [UNESP] De Andrade, Marcelo Barbosa José Tiera, Marcio [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Furuyama Lima, Aline Margarete [UNESP] De Freitas Lima, Marcelo [UNESP] Garrido Assis, Odílio Benedito Raabe, Alice Amoroso, Hemelen Caroline [UNESP] De Oliveira Tiera, Vera Aparecida [UNESP] De Andrade, Marcelo Barbosa José Tiera, Marcio [UNESP] |
description |
In this study, the preparation of porous nanocomposite scaffolds (HX-CNT) from a combination of a hydroxamic derivative of alginate (HX) and an amine-functionalized multiwalled carbon nanotube (CNT) at different concentrations is described. The structure of HX was investigated by FTIR, and the degree of substitution around 9% was confirmed by elemental analysis. The interaction between CNT and alginate derivative in the nanocomposite crosslinked with calcium was confirmed by FTIR, Raman spectroscopy, and SEM. The results obtained in this study showed that scaffolds based on HX-CNT composites with a 4 wt% concentration level exhibited improved physical and mechanical properties compared to plain alginate (Young's modulus increased from 2.2 to 5.1 MPa and elastic strength from 0.13 to 0.25 MPa) and decreased the swelling ratios from ~900 to ~673. The cytotoxicity assays using the L929 cell line proved that the nanocomposite scaffolds were nontoxic, even at the highest CNT concentration. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 2019-10-06T15:35:20Z 2019-10-06T15:35:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2018/4218270 Journal of Nanomaterials, v. 2018. 1687-4129 1687-4110 http://hdl.handle.net/11449/187410 10.1155/2018/4218270 2-s2.0-85062265031 |
url |
http://dx.doi.org/10.1155/2018/4218270 http://hdl.handle.net/11449/187410 |
identifier_str_mv |
Journal of Nanomaterials, v. 2018. 1687-4129 1687-4110 10.1155/2018/4218270 2-s2.0-85062265031 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Nanomaterials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128522223353856 |