Antiangiogenic alkaloids from plants

Detalhes bibliográficos
Autor(a) principal: Lopes, Flávia Cristine Mascia
Data de Publicação: 2013
Outros Autores: Regasini, Luis Octávio [UNESP], de Magalhães Pinheiro Alçada, Manuel Nuno, Soares, Raquel
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/978-3-642-22144-6_48
http://hdl.handle.net/11449/228467
Resumo: Angiogenesis, the formation of new blood vessels from preexisting capillaries, is an important research field. As the understanding of this process increases, this new knowledge will have a significant impact on several angiogenesisdependent diseases. A wide variety of plants are rich in alkaloids, and these compounds have traditionally been of interest due to their pronounced effects on various physiological activities in animals and humans. Nowadays, it is known that many alkaloids obtained from plants exhibit antiangiogenic activity, and these alkaloids may act through different mechanisms to inhibit angiogenesis. Herein, we will discuss the most important alkaloids obtained from plants, focusing especially in their antiangiogenic activity. Because of the great diversity of plants, certainly, there are many antiangiogenic alkaloids that have yet to be discovered.
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spelling Antiangiogenic alkaloids from plantsAlkaloidsAngiogenesisAngiogenesis-dependent diseasesAntiangiogenic activityNatural productsPlantsAngiogenesis, the formation of new blood vessels from preexisting capillaries, is an important research field. As the understanding of this process increases, this new knowledge will have a significant impact on several angiogenesisdependent diseases. A wide variety of plants are rich in alkaloids, and these compounds have traditionally been of interest due to their pronounced effects on various physiological activities in animals and humans. Nowadays, it is known that many alkaloids obtained from plants exhibit antiangiogenic activity, and these alkaloids may act through different mechanisms to inhibit angiogenesis. Herein, we will discuss the most important alkaloids obtained from plants, focusing especially in their antiangiogenic activity. Because of the great diversity of plants, certainly, there are many antiangiogenic alkaloids that have yet to be discovered.Hematology and Hemotherapy Center School of Medical Sciences University of Campinas–UNICAMPDepartment of Organic Chemistry Araraquara Institute of Chemistry São Paulo State University–UNESPDepartment of Biochemistry (U38/FCT) Faculty of Medicine University of PortoDepartment of Organic Chemistry Araraquara Institute of Chemistry São Paulo State University–UNESPUniversidade Estadual de Campinas (UNICAMP)Universidade Estadual Paulista (UNESP)University of PortoLopes, Flávia Cristine MasciaRegasini, Luis Octávio [UNESP]de Magalhães Pinheiro Alçada, Manuel NunoSoares, Raquel2022-04-29T08:26:53Z2022-04-29T08:26:53Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart1439-1467http://dx.doi.org/10.1007/978-3-642-22144-6_48Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes, p. 1439-1467.http://hdl.handle.net/11449/22846710.1007/978-3-642-22144-6_482-s2.0-85037847476Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengNatural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenesinfo:eu-repo/semantics/openAccess2022-04-29T08:26:53Zoai:repositorio.unesp.br:11449/228467Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:44:25.725356Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antiangiogenic alkaloids from plants
title Antiangiogenic alkaloids from plants
spellingShingle Antiangiogenic alkaloids from plants
Lopes, Flávia Cristine Mascia
Alkaloids
Angiogenesis
Angiogenesis-dependent diseases
Antiangiogenic activity
Natural products
Plants
title_short Antiangiogenic alkaloids from plants
title_full Antiangiogenic alkaloids from plants
title_fullStr Antiangiogenic alkaloids from plants
title_full_unstemmed Antiangiogenic alkaloids from plants
title_sort Antiangiogenic alkaloids from plants
author Lopes, Flávia Cristine Mascia
author_facet Lopes, Flávia Cristine Mascia
Regasini, Luis Octávio [UNESP]
de Magalhães Pinheiro Alçada, Manuel Nuno
Soares, Raquel
author_role author
author2 Regasini, Luis Octávio [UNESP]
de Magalhães Pinheiro Alçada, Manuel Nuno
Soares, Raquel
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual Paulista (UNESP)
University of Porto
dc.contributor.author.fl_str_mv Lopes, Flávia Cristine Mascia
Regasini, Luis Octávio [UNESP]
de Magalhães Pinheiro Alçada, Manuel Nuno
Soares, Raquel
dc.subject.por.fl_str_mv Alkaloids
Angiogenesis
Angiogenesis-dependent diseases
Antiangiogenic activity
Natural products
Plants
topic Alkaloids
Angiogenesis
Angiogenesis-dependent diseases
Antiangiogenic activity
Natural products
Plants
description Angiogenesis, the formation of new blood vessels from preexisting capillaries, is an important research field. As the understanding of this process increases, this new knowledge will have a significant impact on several angiogenesisdependent diseases. A wide variety of plants are rich in alkaloids, and these compounds have traditionally been of interest due to their pronounced effects on various physiological activities in animals and humans. Nowadays, it is known that many alkaloids obtained from plants exhibit antiangiogenic activity, and these alkaloids may act through different mechanisms to inhibit angiogenesis. Herein, we will discuss the most important alkaloids obtained from plants, focusing especially in their antiangiogenic activity. Because of the great diversity of plants, certainly, there are many antiangiogenic alkaloids that have yet to be discovered.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2022-04-29T08:26:53Z
2022-04-29T08:26:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/978-3-642-22144-6_48
Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes, p. 1439-1467.
http://hdl.handle.net/11449/228467
10.1007/978-3-642-22144-6_48
2-s2.0-85037847476
url http://dx.doi.org/10.1007/978-3-642-22144-6_48
http://hdl.handle.net/11449/228467
identifier_str_mv Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes, p. 1439-1467.
10.1007/978-3-642-22144-6_48
2-s2.0-85037847476
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1439-1467
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128851047350272

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