The use of nano-enabled technologies to diagnose dengue virus infections

Detalhes bibliográficos
Autor(a) principal: Basso, Caroline R. [UNESP]
Data de Publicação: 2021
Outros Autores: Crulhas, Bruno P. [UNESP], Castro, Gustavo R. [UNESP], Pedrosa, Valber A. [UNESP]
Tipo de documento: Capítulo de livro
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/B978-0-12-821100-7.00021-2
http://hdl.handle.net/11449/245938
Resumo: Neglected diseases are caused by infectious agents or parasites and they are endemic in low-income populations living worldwide. Among these diseases, one finds dengue fever, which affects poor populations living in tropical and subtropical developing countries that report thousands of deaths on a yearly basis. Dengue fever is transmitted to individuals through the bite of contaminated mosquitos, a fact that favors outbreaks at the national scale. Nowadays, dengue diagnosis tests are performed in laboratories, mainly based on serological tests. However, this methodology has limitations such as high cost and the long time necessary to get to the results. Therefore, it is necessary to develop a new reliable and low-cost methodology to enable quick disease diagnosis. Recently, biosensors have emerged in the technological field as analytical tools capable of identifying pathogens based on the use of gold nanoparticles. Therefore, the aim of the current study is to briefly describe restrictions observed in conventional methodologies and the development of new methodologies focused on the fast and effective diagnosis of dengue virus in real serotype samples, based on the use of modified nanostructures; these nanostructures bind to their respective antigens and allow immediate color change. The current article has summarized published studies about fast diagnostic tests used for the biomolecular diagnosis of dengue fever.
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spelling The use of nano-enabled technologies to diagnose dengue virus infectionsBiosensorsDengueDiagnosisNaked-eye detectionNanostructuresNeglected diseases are caused by infectious agents or parasites and they are endemic in low-income populations living worldwide. Among these diseases, one finds dengue fever, which affects poor populations living in tropical and subtropical developing countries that report thousands of deaths on a yearly basis. Dengue fever is transmitted to individuals through the bite of contaminated mosquitos, a fact that favors outbreaks at the national scale. Nowadays, dengue diagnosis tests are performed in laboratories, mainly based on serological tests. However, this methodology has limitations such as high cost and the long time necessary to get to the results. Therefore, it is necessary to develop a new reliable and low-cost methodology to enable quick disease diagnosis. Recently, biosensors have emerged in the technological field as analytical tools capable of identifying pathogens based on the use of gold nanoparticles. Therefore, the aim of the current study is to briefly describe restrictions observed in conventional methodologies and the development of new methodologies focused on the fast and effective diagnosis of dengue virus in real serotype samples, based on the use of modified nanostructures; these nanostructures bind to their respective antigens and allow immediate color change. The current article has summarized published studies about fast diagnostic tests used for the biomolecular diagnosis of dengue fever.Institute of Bioscience UNESP-Botucatu, SPInstitute of Bioscience UNESP-Botucatu, SPUniversidade Estadual Paulista (UNESP)Basso, Caroline R. [UNESP]Crulhas, Bruno P. [UNESP]Castro, Gustavo R. [UNESP]Pedrosa, Valber A. [UNESP]2023-07-29T12:27:16Z2023-07-29T12:27:16Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart71-88http://dx.doi.org/10.1016/B978-0-12-821100-7.00021-2Applications of Nanobiotechnology for Neglected Tropical Diseases, p. 71-88.http://hdl.handle.net/11449/24593810.1016/B978-0-12-821100-7.00021-22-s2.0-85138403285Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengApplications of Nanobiotechnology for Neglected Tropical Diseasesinfo:eu-repo/semantics/openAccess2023-07-29T12:27:16Zoai:repositorio.unesp.br:11449/245938Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:25:45.025571Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The use of nano-enabled technologies to diagnose dengue virus infections
title The use of nano-enabled technologies to diagnose dengue virus infections
spellingShingle The use of nano-enabled technologies to diagnose dengue virus infections
Basso, Caroline R. [UNESP]
Biosensors
Dengue
Diagnosis
Naked-eye detection
Nanostructures
title_short The use of nano-enabled technologies to diagnose dengue virus infections
title_full The use of nano-enabled technologies to diagnose dengue virus infections
title_fullStr The use of nano-enabled technologies to diagnose dengue virus infections
title_full_unstemmed The use of nano-enabled technologies to diagnose dengue virus infections
title_sort The use of nano-enabled technologies to diagnose dengue virus infections
author Basso, Caroline R. [UNESP]
author_facet Basso, Caroline R. [UNESP]
Crulhas, Bruno P. [UNESP]
Castro, Gustavo R. [UNESP]
Pedrosa, Valber A. [UNESP]
author_role author
author2 Crulhas, Bruno P. [UNESP]
Castro, Gustavo R. [UNESP]
Pedrosa, Valber A. [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Basso, Caroline R. [UNESP]
Crulhas, Bruno P. [UNESP]
Castro, Gustavo R. [UNESP]
Pedrosa, Valber A. [UNESP]
dc.subject.por.fl_str_mv Biosensors
Dengue
Diagnosis
Naked-eye detection
Nanostructures
topic Biosensors
Dengue
Diagnosis
Naked-eye detection
Nanostructures
description Neglected diseases are caused by infectious agents or parasites and they are endemic in low-income populations living worldwide. Among these diseases, one finds dengue fever, which affects poor populations living in tropical and subtropical developing countries that report thousands of deaths on a yearly basis. Dengue fever is transmitted to individuals through the bite of contaminated mosquitos, a fact that favors outbreaks at the national scale. Nowadays, dengue diagnosis tests are performed in laboratories, mainly based on serological tests. However, this methodology has limitations such as high cost and the long time necessary to get to the results. Therefore, it is necessary to develop a new reliable and low-cost methodology to enable quick disease diagnosis. Recently, biosensors have emerged in the technological field as analytical tools capable of identifying pathogens based on the use of gold nanoparticles. Therefore, the aim of the current study is to briefly describe restrictions observed in conventional methodologies and the development of new methodologies focused on the fast and effective diagnosis of dengue virus in real serotype samples, based on the use of modified nanostructures; these nanostructures bind to their respective antigens and allow immediate color change. The current article has summarized published studies about fast diagnostic tests used for the biomolecular diagnosis of dengue fever.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
2023-07-29T12:27:16Z
2023-07-29T12:27:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bookPart
format bookPart
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/B978-0-12-821100-7.00021-2
Applications of Nanobiotechnology for Neglected Tropical Diseases, p. 71-88.
http://hdl.handle.net/11449/245938
10.1016/B978-0-12-821100-7.00021-2
2-s2.0-85138403285
url http://dx.doi.org/10.1016/B978-0-12-821100-7.00021-2
http://hdl.handle.net/11449/245938
identifier_str_mv Applications of Nanobiotechnology for Neglected Tropical Diseases, p. 71-88.
10.1016/B978-0-12-821100-7.00021-2
2-s2.0-85138403285
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Applications of Nanobiotechnology for Neglected Tropical Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 71-88
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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