Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos

Detalhes bibliográficos
Autor(a) principal: SOUSA, Rodrigo Vital Gouveia de
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRPE
Texto Completo: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8897
Resumo: Sedation, as well as chemical restraint, is extremely important in Veterinary Ophthalmology, and it is very common to care for non-cooperative animals in the routine of feline ophthalmologists. It is believed that severe eye pain may act as a detrimental factor when performing a complete eye examination. For these reasons, the need to understand the effects of dissociative anesthetic agents, under the feline eye system, specifically on intraocular pressure, is of paramount importance. The objective of this study was to evaluate the effects the chemical restraint promoted by the use of dextrocetamine in combination with midazolam, intramuscularly, under intraocular pressure in healthy cats, treated at the Hospital Veterinary University (HVU), from the Federal University of Agreste of Pernambuco (UFAPE), tutored by the Rural Federal University of Pernambuco (UFRPE). The prospective study included 13 felines selected from the HVU care routine, which comprised the two experimental moments, both the T0 (pre-sedation) and the T10 (post-sedation) moment, where heart rate measurements were made ( HR), respiratory rate (RR), systolic arterial pressure (SAP) and intraocular pressure (IOP) of each patient at both times. All experimental groups were subjected to the Shapiro Wilk´s test in order to indicate whether the groups have a normal distribution, and from these data, and the statistical analysis of the data was performed using the version of the Stats Tester application, developed for Android Operating System. The results obtained in this study for mean intraocular pressure at T0 was 17.34 ± 3.09 mmHg and for T10 it was 17.80 ± 3.04, where no statistically significant difference was observed in the comparison between the moments studied. It is concluded that the combination of dextrocetamine and midazolam can be considered as a chemical containment protocol for non-cooperative patients in routine ophthalmic clinical evaluations for the species under study.
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spelling SÁ, Fabrício Bezerra deFERRI, Rinaldo CavalcanteHENRIQUE, Fernanda Vieirahttp://lattes.cnpq.br/0133039074213808SOUSA, Rodrigo Vital Gouveia de2023-03-28T17:52:55Z2020-02-17SOUSA, Rodrigo Vital Gouveia de. Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos. 2020. 64 f. Dissertação (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8897Sedation, as well as chemical restraint, is extremely important in Veterinary Ophthalmology, and it is very common to care for non-cooperative animals in the routine of feline ophthalmologists. It is believed that severe eye pain may act as a detrimental factor when performing a complete eye examination. For these reasons, the need to understand the effects of dissociative anesthetic agents, under the feline eye system, specifically on intraocular pressure, is of paramount importance. The objective of this study was to evaluate the effects the chemical restraint promoted by the use of dextrocetamine in combination with midazolam, intramuscularly, under intraocular pressure in healthy cats, treated at the Hospital Veterinary University (HVU), from the Federal University of Agreste of Pernambuco (UFAPE), tutored by the Rural Federal University of Pernambuco (UFRPE). The prospective study included 13 felines selected from the HVU care routine, which comprised the two experimental moments, both the T0 (pre-sedation) and the T10 (post-sedation) moment, where heart rate measurements were made ( HR), respiratory rate (RR), systolic arterial pressure (SAP) and intraocular pressure (IOP) of each patient at both times. All experimental groups were subjected to the Shapiro Wilk´s test in order to indicate whether the groups have a normal distribution, and from these data, and the statistical analysis of the data was performed using the version of the Stats Tester application, developed for Android Operating System. The results obtained in this study for mean intraocular pressure at T0 was 17.34 ± 3.09 mmHg and for T10 it was 17.80 ± 3.04, where no statistically significant difference was observed in the comparison between the moments studied. It is concluded that the combination of dextrocetamine and midazolam can be considered as a chemical containment protocol for non-cooperative patients in routine ophthalmic clinical evaluations for the species under study.A sedação, bem como a contenção química, é de extrema importância na Oftalmologia Veterinária sendo muito comum o atendimento de animais não cooperativos na rotina do oftalmologista de felinos. Acredita-se que a dor ocular intensa possa agir como um fator prejudicial na realização de um exame oftálmico completo. Por estas razões, a necessidade de compreender os efeitos dos agentes anestésicos dissociativos, sob o sistema ocular de felinos, especificamente na pressão intraocular, é de suma importância. Objetivou-se com o presente estudo avaliar os efeitos da contenção química promovida pela utilização de dextrocetamina em associação com o midazolam, por via intramuscular, sob a pressão intraocular em felinos hígidos, atendidos no Hospital Veterinário Universitário (HVU), da Universidade Federal do Agreste de Pernambuco (UFAPE), tutoreado pela Universidade Federal Rural de Pernambuco (UFRPE). No estudo prospectivo foram incluídos 13 felinos selecionados da rotina de atendimento do HVU, que compuseram os dois momentos experimentais, tanto o momento T0 (Pré-sedação) quanto o momento T10 (Pós-sedação), onde se realizaram mensurações, de frequência cardíaca (FC), frequência respiratória (FR), pressão arterial sistólica (PAS) e pressão intraocular (PIO) de cada paciente em ambos os momentos. Todos os grupos experimentais foram submetidos ao teste de Shapiro Wilk´s com o propósito de indicar se os grupos possuem uma distribuição normal, e a partir desses dados, e a análise estatística dos dados foi realizada utilizando a versão do aplicativo Stats Tester, desenvolvido para Sistema Operacional Android. Os resultados obtidos neste estudo para pressão intraocular média em T0 foi de 17,34 ± 3,09 mmHg e para T10 foi de 17,80 ± 3,04, onde não foi observado diferença estatística significativa na comparação entre os momentos estudados. Conclui-se que a associação de dextrocetamina e midazolam pode ser considerada como protocolo de contenção química para pacientes não cooperativos nas avaliações clínicas oftalmológicas de rotina para a espécie em estudo.Submitted by (lucia.rodrigues@ufrpe.br) on 2023-03-28T17:52:55Z No. of bitstreams: 1 Rodrigo Vital Gouveia de Sousa.pdf: 1327463 bytes, checksum: b2893ca51ec6f8f1e5362426853ccdad (MD5)Made available in DSpace on 2023-03-28T17:52:55Z (GMT). No. of bitstreams: 1 Rodrigo Vital Gouveia de Sousa.pdf: 1327463 bytes, checksum: b2893ca51ec6f8f1e5362426853ccdad (MD5) Previous issue date: 2020-02-17application/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em Ciência VeterináriaUFRPEBrasilDepartamento de Medicina VeterináriaGatoGlaucomaOftalmologia veterináriaTonometriaAnestesia dissociativaDextrocetaminaMidazolamCIENCIAS AGRARIAS::MEDICINA VETERINARIAViabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-3061482854177903105600600600-3020210563763616780453670264235017319info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRPEinstname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEORIGINALRodrigo Vital Gouveia de Sousa.pdfRodrigo Vital Gouveia de Sousa.pdfapplication/pdf942664http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8897/2/Rodrigo+Vital+Gouveia+de+Sousa.pdf3fa0ab34b7b9e09018a5ce4aad986cd2MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8897/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede2/88972023-03-29 09:39:33.522oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.tede2.ufrpe.br:8080/tede/PUBhttp://www.tede2.ufrpe.br:8080/oai/requestbdtd@ufrpe.br ||bdtd@ufrpe.bropendoar:2024-05-28T12:37:34.200014Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)false
dc.title.por.fl_str_mv Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
title Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
spellingShingle Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
SOUSA, Rodrigo Vital Gouveia de
Gato
Glaucoma
Oftalmologia veterinária
Tonometria
Anestesia dissociativa
Dextrocetamina
Midazolam
CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
title_full Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
title_fullStr Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
title_full_unstemmed Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
title_sort Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos
author SOUSA, Rodrigo Vital Gouveia de
author_facet SOUSA, Rodrigo Vital Gouveia de
author_role author
dc.contributor.advisor1.fl_str_mv SÁ, Fabrício Bezerra de
dc.contributor.advisor-co1.fl_str_mv FERRI, Rinaldo Cavalcante
dc.contributor.referee1.fl_str_mv HENRIQUE, Fernanda Vieira
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0133039074213808
dc.contributor.author.fl_str_mv SOUSA, Rodrigo Vital Gouveia de
contributor_str_mv SÁ, Fabrício Bezerra de
FERRI, Rinaldo Cavalcante
HENRIQUE, Fernanda Vieira
dc.subject.por.fl_str_mv Gato
Glaucoma
Oftalmologia veterinária
Tonometria
Anestesia dissociativa
Dextrocetamina
Midazolam
topic Gato
Glaucoma
Oftalmologia veterinária
Tonometria
Anestesia dissociativa
Dextrocetamina
Midazolam
CIENCIAS AGRARIAS::MEDICINA VETERINARIA
dc.subject.cnpq.fl_str_mv CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Sedation, as well as chemical restraint, is extremely important in Veterinary Ophthalmology, and it is very common to care for non-cooperative animals in the routine of feline ophthalmologists. It is believed that severe eye pain may act as a detrimental factor when performing a complete eye examination. For these reasons, the need to understand the effects of dissociative anesthetic agents, under the feline eye system, specifically on intraocular pressure, is of paramount importance. The objective of this study was to evaluate the effects the chemical restraint promoted by the use of dextrocetamine in combination with midazolam, intramuscularly, under intraocular pressure in healthy cats, treated at the Hospital Veterinary University (HVU), from the Federal University of Agreste of Pernambuco (UFAPE), tutored by the Rural Federal University of Pernambuco (UFRPE). The prospective study included 13 felines selected from the HVU care routine, which comprised the two experimental moments, both the T0 (pre-sedation) and the T10 (post-sedation) moment, where heart rate measurements were made ( HR), respiratory rate (RR), systolic arterial pressure (SAP) and intraocular pressure (IOP) of each patient at both times. All experimental groups were subjected to the Shapiro Wilk´s test in order to indicate whether the groups have a normal distribution, and from these data, and the statistical analysis of the data was performed using the version of the Stats Tester application, developed for Android Operating System. The results obtained in this study for mean intraocular pressure at T0 was 17.34 ± 3.09 mmHg and for T10 it was 17.80 ± 3.04, where no statistically significant difference was observed in the comparison between the moments studied. It is concluded that the combination of dextrocetamine and midazolam can be considered as a chemical containment protocol for non-cooperative patients in routine ophthalmic clinical evaluations for the species under study.
publishDate 2020
dc.date.issued.fl_str_mv 2020-02-17
dc.date.accessioned.fl_str_mv 2023-03-28T17:52:55Z
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dc.identifier.citation.fl_str_mv SOUSA, Rodrigo Vital Gouveia de. Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos. 2020. 64 f. Dissertação (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.
dc.identifier.uri.fl_str_mv http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8897
identifier_str_mv SOUSA, Rodrigo Vital Gouveia de. Viabilidade do protocolo de contenção farmacológica com dextrocetamina associada ao midazolam, por via intramuscular, para avaliação oftálmica em felinos. 2020. 64 f. Dissertação (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.
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dc.publisher.department.fl_str_mv Departamento de Medicina Veterinária
publisher.none.fl_str_mv Universidade Federal Rural de Pernambuco
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